Publications by authors named "Sofia E Murillo"
The purpose of this study was to examine the effect of topical and/or oral angiotensin converting enzyme II inhibitor and TGF-beta signaling blocker losartan on corneal stromal fibrosis that developed in rabbit corneas after Descemetorhexis removal of central Descemet's membrane and corneal endothelium. Twenty-eight New Zealand white rabbits were included and either had 8 mm central Descemetorhexis or sham control surgery without Descemetorhexis in one eye. Groups of 4 eyes without Descemetorhexis were treated for one month with no medications, topical losartan or oral losartan.
View Article and Find Full Text PDFArticle Synopsis
- The report highlights three cases of acute corneal edema that emerged decades after penetrating keratoplasty (PK) in patients with keratoconus who were wearing scleral contact lenses (ScCLs).
- A retrospective review examined symptoms, medical history, and testing results of the patients experiencing sudden eye pain and vision loss after refitting into ScCLs.
- The findings indicate a possible link between the refitting of ScCLs and the development of acute hydrops in previously stable corneal grafts, raising awareness about the risks involved in such lens fittings.