Publications by authors named "Sofia Battistini"
Although the usual primary clinical manifestation of Coronavirus disease (COVID-19) is respiratory, several non-respiratory symptoms have been described, including neuropsychiatric ones. The aim of this study was to investigate the mid-term mental health outcomes in patients recovered from COVID-19, 3-4 months after discharge from the University Hospital Maggiore della Carità, Novara, Italy. Furthermore, we investigated the possible association of the mid-term mental health consequences of the COVID-19 infection with patients' clinical current status, persistent physical impairment and severity of acute phase of the disease.
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- The study focuses on understanding the varied prognosis of COVID-19 by identifying clinical and laboratory indicators that can predict poor outcomes in hospitalized patients.
- Researchers analyzed data from 664 COVID-19 patients in Northern Italy, discovering that factors like red cell distribution width (RDW), neutrophil-to-lymphocyte (NL) ratio, and platelet count are significant predictors of in-hospital mortality.
- The results suggest that using simple blood tests could help in classifying the severity of COVID-19, ultimately guiding treatment and monitoring strategies for better patient management.
Importance: Although plenty of data exist regarding clinical manifestations, course, case fatality rate, and risk factors associated with mortality in severe coronavirus disease 2019 (COVID-19), long-term respiratory and functional sequelae in survivors of COVID-19 are unknown.
Objective: To evaluate the prevalence of lung function anomalies, exercise function impairment, and psychological sequelae among patients hospitalized for COVID-19, 4 months after discharge.
Design, Setting, And Participants: This prospective cohort study at an academic hospital in Northern Italy was conducted among a consecutive series of patients aged 18 years and older (or their caregivers) who had received a confirmed diagnosis of severe acute respiratory coronavirus 2 (SARS-CoV-2) infection severe enough to require hospital admission from March 1 to June 29, 2020.
Article Synopsis
- The study examined COVID-19 case fatality rates (CFR) and mortality predictors in Northern Italy during March-April 2020.
- Out of 1,697 hospitalized patients, 504 died, resulting in an overall CFR of 29.7%.
- Key predictors of mortality identified were age, cancer diagnosis, obesity, and smoking, with laboratory data reinforcing the significance of age, cancer diagnosis, and baseline PaO/FiO ratio.