Publications by authors named "Sofia Alexandra Gaspar Santos"
Neuroplasticity induced by general anaesthesia: study protocol for a randomised cross-over clinical trial exploring the effects of sevoflurane and propofol on the brain - A 3-T magnetic resonance imaging study of healthy volunteers.
Signe Sloth Madsen Kirsten Møller Karsten Skovgaard Olsen Mark Bitsch Vestergaard Ulrich Lindberg Sofia Alexandra Gaspar Santos
Trials
September 2020
Article Synopsis
- This project investigates the effects of two types of general anesthesia—sevoflurane (inhaled) and propofol (intravenous)—on neuroplastic changes in the brain and their potential links to cognitive dysfunction and feelings of fatigue and well-being.
- The study involves a randomized, blinded clinical trial with 30 healthy volunteers undergoing brain imaging and cognitive tests before and after each type of anesthesia.
- The outcomes will include structural brain changes, functional MRI results, and correlations with cognitive and psychological assessments, aiming to clarify how different anesthesia types may affect brain function post-surgery.