Publications by authors named "Soerheim I"
Article Synopsis
- The study highlights the importance of identifying gene-by-environment interactions in understanding the genetics of chronic obstructive pulmonary disease (COPD), particularly regarding the relationship between smoking exposure and lung function.
- Non-linear relationships between smoking pack-years and forced expiratory volume (FEV(1)) were found in four large cohorts, suggesting that a piecewise linear model is more effective than the standard total pack-years model for analyzing these interactions.
- The research concluded that utilizing approaches that account for non-linearity can enhance the accuracy and power of genetic association studies, leading to better insights into COPD susceptibility and variations based on smoking exposure.
