Two-year fixation and ten-year clinical outcomes of total knee arthroplasty inserted with normal-curing bone cement and slow-curing bone cement: A randomized controlled trial in 54 patients.

Background: The normal-curing Refobacin® Bone Cement R (RR) and slow-curing Refobacin® Plus Bone Cement (RP) were introduced after discontinuation of the historically most used bone cement, Refobacin®-Palacos® R, in 2005. The aim of this study was to compare total knee arthroplasty component fixation with the two bone cements.

Methods: 54 patients with primary knee osteoarthritis were randomized to either RR (N = 27) or RP (N = 27) bone cement and followed for two years with radiostereometric analysis of tibial and femoral component migration and dual-energy x-ray absorptiometry measured periprosthetic bone mineral density (BMD).

Implant fracture of the Regenerex® modular metal tibial component: A report of three cases.

Background: Implant fractures are a very rare complication in primary total knee replacement (TKR) surgery and with modern implant designs and improved metals these events have nearly been eliminated. In this case series we report three cases of tibial metal baseplate fractures in uncemented Regenerex® TKR.

Methods: Cases originated from a prospective case series of 80 patients operated between 2013 and 2016.

Radionuclide Diagnosis of Pulmonary Embolism.

Diagnostic imaging plays an integral role in the diagnostic workup of suspected pulmonary embolism, and several modalities have been employed over the years. In recent years, the choice has been narrowed to either computer tomographic or radionuclide based methods, i.e.

Symptomatology, Clinical Presentation and Basic Work up in Patients with Suspected Pulmonary Embolism.

Basic knowledge of pulmonary embolism is relevant to most practicing physicians. Many medical specialties care for patients with increased risk of pulmonary embolism, why recognition of relevant symptoms, a thorough medical history, assessment of the clinical condition of the patient and possibly referral to a relevant facility should be a part of the skills of all clinicians. Sudden onset dyspnea, chest pain, syncope and hemoptysis are essential symptoms of pulmonary embolism, and in most of these patients basic investigations like arterial blood gas analysis, electrocardiogram, chest x-ray and biochemical analyses are appropriate.

Balancing of lipid, protein, and carbohydrate intake in a predatory beetle following hibernation, and consequences for lipid restoration.

Carnivorous animals are known to balance their consumption of lipid and protein, and recent studies indicate that some mammalian carnivores also regulate their intake of carbohydrate. We investigated macronutrient balancing and lipid restoration following hibernation in the ground beetle Anchomenus dorsalis, hypothesizing that carbohydrates might be important energy sources upon hibernation when predator lipid stores are exhausted and prey are equally lean. We recorded the consumption of lipid, protein, and carbohydrate over nine days following hibernation, as the beetles foraged to refill their lipid stores.

Cardiac sympathetic imaging with mIBG in cirrhosis and portal hypertension: relation to autonomic and cardiac function.

Autonomic and cardiac dysfunction is frequent in cirrhosis and includes increased sympathetic nervous activity, impaired heart rate variability (HRV), and baroreflex sensitivity (BRS). Quantified (123)I-metaiodobenzylguanidine (mIBG) scintigraphy reflects cardiac noradrenaline uptake, and in patients with cardiac failure it predicts outcome. In this study, we aimed to investigate cardiac sympathetic neuronal function in cirrhosis by mIBG scintigraphy in relation to cardiovascular function.

Pulmonary dysfunction and hepatopulmonary syndrome in cirrhosis and portal hypertension.

Background: Pulmonary dysfunction including the hepatopulmonary syndrome (HPS) is an important complication to cirrhosis and portal hypertension. However, the precise relation to liver dysfunction and the prevalence of HPS are unclear.

Aims: We therefore aimed to assess (i) the prevalence of HPS in consecutive alcoholic cirrhotic patients, (ii) the degree of pulmonary dysfunction in relation to liver function and (iii) the response of a 100% oxygen test on cardiopulmonary and peripheral oxygenation.

Outcome of splanchnic blood flow determination in patients with suspected chronic intestinal ischaemia. A retrospective survey.

Background: Different diagnostic examinations have been applied in the management of patients with suspected intestinal ischaemia. In some centres, invasive determination of a meal-induced increase in splanchnic blood flow is used in the diagnostic process and in the selection of patients for surgery. However, no studies have evaluated the impact of splanchnic blood flow determination on therapy in such patients.