Development of a clinical practice guideline on pressure ulcers in people with spinal cord injuries inspired by the ADAPTE method.

Study Design: Guideline adaptation study using the ADAPTE method.

Objective: The aim of this study was the development and validation of a Danish clinical practice guideline for PU/PI prevention and treatment for people with SCI through adaptation of existing guidelines.

Methods: The ADAPTE method is a systematic framework used to adapt existing clinical practice guidelines to a new context, such as a different healthcare setting or population.

"I am just trying to live a life!" -a qualitative study of the lived experience of pressure ulcers in people with spinal cord injuries.

Background: Pressure ulcers (PUs) are frequently reported in people with spinal cord injuries (SCI). Wound management in people with SCI involves relieving pressure on the affected area by means of immobilisation and bed rest. The healing time of a PU can vary, but often takes several months or even years, causing people to stay in bed for prolonged periods of time.

Interventions, stakeholders, and organisation related to pressure ulcer prevention for individuals with spinal cord injuries in transition from hospital to home - A scoping review.

Study Design: Scoping review.

Aim Of The Study: To obtain an overview of initiatives, organisational components, and stakeholders' perspectives on PU prevention in transitional care.

Methods: Scoping review searching the databases: MEDLINE, EMBASE), CINAHL, Cochrane Library, Web of Science, and SCOPUS in May 2022.

Static overlays for pressure ulcer prevention: a hospital-based health technology assessment.

Introduction: At Odense University Hospital (OUH) alternating-air mattresses (AAM) are used in the prevention of pressure ulcers (PU); however, static overlays might be more effective and have lower costs. To investigate the properties and consequences of using static overlays for prevention of PU at OUH, a hospital-based health technology assessment (HTA) was conducted.

Methods: Two types of static overlays were tested in an observational study and compared with AAM for patients with a medium-high risk of PU in geriatric and orthopaedic wards at OUH.

Pressure ulcer prevention in hospitals: a successful nurse-led clinical quality improvement intervention.

A pressure ulcer prevalence of 17.3% at Odense University Hospital in Denmark in 2010 prompted action and a quality improvement project was planned. This had two aims: to reduce pressure ulcers at the hospital by 50% and to have no pressure ulcers at or above category 3.

Digestibility and clover proportion determine milk production when silages of different grass and clover species are fed to dairy cows.

This study examined how silages of different grass and clover species affect dry matter (DM) intake, milk production, and eating behavior in dairy cows. The primary growth of perennial ryegrass (early and late harvested), festulolium, tall fescue, red clover, and white clover swards were cut, wilted, and ensiled without additives. Thirty-six Danish Holstein cows were fed ad libitum with total mixed rations containing 70% forage on DM basis in an incomplete Latin square design.

Warts Signaling Controls Organ and Body Growth through Regulation of Ecdysone.

Coordination of growth between individual organs and the whole body is essential during development to produce adults with appropriate size and proportions [1, 2]. How local organ-intrinsic signals and nutrient-dependent systemic factors are integrated to generate correctly proportioned organisms under different environmental conditions is poorly understood. In Drosophila, Hippo/Warts signaling functions intrinsically to regulate tissue growth and organ size [3, 4], whereas systemic growth is controlled via antagonistic interactions of the steroid hormone ecdysone and nutrient-dependent insulin/insulin-like growth factor (IGF) (insulin) signaling [2, 5].

Forbs enhance productivity of unfertilised grass-clover leys and support low-carbon bioenergy.

Intensively managed grasslands are dominated by highly productive grass-clover mixtures. Increasing crop diversity by inclusion of competitive forbs may enhance biomass production and sustainable biofuel production. Here we examined if one or all of three forbs (chicory, Cichorium intybus L.

Dry matter yield, chemical composition and estimated extractable protein of legume and grass species during the spring growth.

Background: Knowledge of the variation of extractable protein amount in legumes and grasses as affected by harvest time is important for identifying optimal combinations to enable a high protein production in a biorefinery. The extractability of protein was estimated using the Cornell Net Carbohydrate and Protein System across six harvests during the spring growth.

Results: The estimated extractable protein [g kg dry matter (DM)] defined as the easily available fractions B +B was significantly higher in white clover and lucerne at all harvests while, if the more cell wall attached fraction B can be extracted, white clover had the highest extractable protein amongst all species.

Species Diversity Effects on Productivity, Persistence and Quality of Multispecies Swards in a Four-Year Experiment.

Plant species diversity may benefit natural grassland productivity, but its effect in managed grassland systems is not well understood. A four-year multispecies grassland experiment was conducted to investigate the effect of species diversity-legumes and non-leguminous forbs-on productivity, persistence and sward quality under cutting or grazing regimes and with or without slurry application. Three mixtures were established- 3-mix: grass, red and white clover, 10-mix: 3-mix plus birdsfoot trefoil and six non-leguminous forbs, and 12-mix: 10-mix plus lucerne and festulolium.

Effects of maturity and harvest season of grass-clover silage and of forage-to-concentrate ratio on milk production of dairy cows.

This study examined the effects of maturity and season of harvest of grass-clover silages and forage:concentrate ratio (FCR) on feed intake, milk production, chewing activity, digestibility, and fecal consistency of Holstein dairy cows. Comparison included 2 cuts in spring season (early and late) and 2 cuts in summer season (early and late) combined with high FCR (80:20; HFCR) and low FCR (50:50; LFCR). The experiment included 24 lactating Holstein cows arranged as 2 repeated 4 × 4 Latin squares with four 21-d periods and included measurements of feed composition, feed intake, milk production and composition, chewing activities, digestibilities, and fecal dry matter (DM) concentration and scoring.

Biogas potential from forbs and grass-clover mixture with the application of near infrared spectroscopy.

This study investigated the potentials of forbs; caraway, chicory, red clover and ribwort plantain as substrates for biogas production. One-, two- and four-cut systems were implemented and the influence on dry matter yields, chemical compositions and methane yields were examined. The two- and four-cut systems resulted in higher dry matter yields (kg [total solid, TS] ha(-1)) compared to the one-cut system.

Interrelations between herbage yield, α-tocopherol, β-carotene, lutein, protein, and fiber in non-leguminous forbs, forage legumes, and a grass-clover mixture as affected by harvest date.

Pastures with diverse botanical composition may enhance animal-derived product quality. A recent study demonstrated high vitamin concentrations and yields in some forb species. The objectives of the present study were to investigate interrelations between herbage yields, vitamin concentrations, protein and fiber contents and analyze the effect of harvest date.

Fatty acids, α-tocopherol, β-carotene, and lutein contents in forage legumes, forbs, and a grass-clover mixture.

Fresh forages are an important natural source of vitamins and fatty acids in ruminant diets, and their concentrations in forage species are important for the quality of animal-derived foods such as dairy and meat products. The aims of this study were to obtain novel information on vitamins and fatty acids (FA) in a variety of forage legumes and non-legume forb species compared to a grass-clover mixture and to explore implications for animal-derived products. Seven dicotyledons [four forbs (salad burnet ( Sanguisorba minor ), caraway ( Carum carvi ), chicory ( Cichorium intybus ), and ribwort plantain ( Plantago lanceolata )) and three legume species (yellow sweet clover ( Melilotus officinalis ), lucerne ( Medicago sativa ), and birdsfoot trefoil ( Lotus corniculatus ))] and a perennial ryegrass-white clover mixture were investigated in a cutting trial with four harvests (May-October) during 2009 and 2010.

Fatty acid, tocopherol and carotenoid content in herbage and milk affected by sward composition and season of grazing.

Background: The aim of the present work was to study to what extent grazing large amounts of white clover (WCL), red clover (RCL), lucerne (LUC) or chicory (CHI) was suitable for production of bovine milk with a high milk fat content of tocopherols, carotenoids, α-linolenic acid and conjugated linoleic acid.

Results: WCL, RCL, LUC and CHI swards were established to investigate the influence of herbage composition on the milk quality of grazing dairy cows at three periods. Average milk fat composition showed high concentrations of linolenic acid (12 mg g⁻¹), conjugated linoleic acid (13 mg g⁻¹), carotenoids (6 µg g⁻¹) and α-tocopherol (21 µg g⁻¹ milk fat).

Optimal care for diabetes and vascular disease: lessons from the field.

Minnesota has led the nation in development of evidence-based guidelines and in public reporting of performance on quality measures. A recent qualitative study explored what 21 Minnesota clinics and their affiliated medical groups are doing to provide patients with optimal diabetes and vascular care. This article reports the practices medical directors and administrators identified as contributing to the successful management of patients with these conditions.

Phyto-oestrogens in herbage and milk from cows grazing white clover, red clover, lucerne or chicory-rich pastures.

A grazing experiment was carried out to study the concentration of phyto-oestrogens in herbage for cattle and in milk during two periods (May and June). Forty-eight Danish Holstein cows were divided into four groups with four treatment diets; white clover, red clover, lucerne and chicory-rich pastures. Each experimental period lasted 15 days.

Effect of time at pasture combined with restricted indoor feeding on production and behaviour in dairy cows.

Extremely high nutrient loads have been reported in grazed grassland regimes compared with cutting regimes in some dairy systems that include the use of supplemental feeding. The aim of this study was, therefore, to investigate the effects on productivity and behaviour of high-yielding dairy cows with limited access to indoor feed and restriction in the time at pasture in a continuous stocking system. During a 6-week period from the start of the grazing season 2005, an experiment was conducted with the aim of investigating the effect of restrictive indoor feeding combined with limiting the time at pasture on the productivity and behaviour of high-yielding dairy cows (31.

Pallister-Killian syndrome: Multiband FISH of tetrasomy 12p.

Two patients with mosaicism for tetrasomy 12p are described. One was diagnosed at the age of 14 years with severe mental retardation and other dysmorphologic findings and abnormal skin pigmentation. Chromosome analysis of a blood sample showed a normal female karyotype.