Publications by authors named "Socorro Mendez Martinez"
Article Synopsis
- * The study reviewed 13 documents from different countries that provide guidelines for detecting IEMs, noting significant variability in the number of disorders screened for (from 4 to 61), with common ones including congenital hypothyroidism and phenylketonuria.
- * Detection guidelines are influenced by individual country policies, disorder incidence, and available resources, highlighting the lack of a universal standard but a shared goal of early detection, diagnosis, and treatment across programs.
Background: The Administrative Work Program at the Center for Educational Research and Teacher Training (CIEFD) was based on the approach of the administrative area to publicize the aspects covered by the environment and the daily operation of the Unit, since all of this is an essential part In order for the CIEFD to function correctly, it must also be verified that the work within the organization is carried out correctly and that each element fulfills its functions.
Objetive: Describe the different aspects of the administrative work program of the Center for Educational Research and Teacher Training in Puebla.
Material And Methods: Qualitative narrative study that describes each of the important administrative areas in the CIEFD: Financial Resources, Material Resources, Human Resources, Conservation and Maintenance, Civil Protection, Competitiveness Model and IT Coordination.
Diabetic cardiomyopathy (DCM) is a complication of type 2 diabetes mellitus (T2DM) capable of progressing to the development of symptomatic heart failure (HF), independently of traditional risk factors for it, such as coronary artery disease and hypertension. There is no specific treatment for DCM; however, sodium-glucose cotransporter 2 inhibitors (SGLT2i) are hypoglycemic drugs that act on SGLT2 channels, inhibiting glucose reabsorption in the kidney. In addition, they have cardioprotective effects, which is why their mechanisms at the cardiac level have been studied.
View Article and Find Full Text PDFMonkeypox, also known as Mpox, is a zoonotic disease endemic to central and western Africa. Following the successful eradication of human smallpox, Mpox has emerged as the primary poxvirus-related illness. In May 2022, an outbreak of Mpox was reported in the United Kingdom.
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- The study aimed to assess the risk of diabetes mellitus (DM) in patients with systemic lupus erythematosus (SLE) and the effects of various SLE treatments on this risk.
- After analyzing 37 studies with over 266,000 SLE patients, results indicated that SLE patients did not have a significantly higher risk of developing DM compared to controls.
- Notably, the use of antimalarials was linked to a lower risk of diabetes, while glucocorticoid treatment was associated with a higher risk of developing the condition.
Antiphospholipid antibody syndrome (usually named antiphospholipid syndrome, APS) is an autoimmune disorder seen mainly in young people. Clinically, APS is described by pregnancy complications and/or a hypercoagulable state, including the venous or arterial vasculature, and strongly related to antiphospholipid antibodies. Although several cardiac manifestations have been involved with APS, and accelerated atherosclerosis is present in this condition, little is known about cardiovascular (CV) risk and the relation between APS.
View Article and Find Full Text PDFObjective: To describe the results from the Global Burden Disease (GBD) study 2019 on the burden of other musculoskeletal (MSK) disorders in Latin America and the Caribbean (LAC).
Methods: In this cross-sectional study, we analyzed data from all LAC region in the GBD study from 1990 to 2019. Other MSK (other than rheumatoid arthritis, osteoarthritis, gout, low back pain, and neck pain) burden was measured as prevalence, mortality, years lived with disability (YLD), and disability-adjusted life (DALY), by year, sex, and country.
Article Synopsis
- This study investigated the trends and disease burden of musculoskeletal (MSK) disorders in Mexico from 1990 to 2019, using data from the Global Burden of Disease Study 2019.
- In 2019, there were approximately 4.8 million new cases of MSK disorders and the condition became the leading cause of years lived with disability (YLD) in Mexico, showing a significant increase over the years.
- The rise in MSK disorders is linked to risk factors like poor occupational ergonomics and high body mass index (BMI), indicating a need for better assessment and management strategies.
Article Synopsis
- * In a study of 110 SLE patients over 8 years, 50.1% achieved LDAS, leading to significantly lower incident VF rates, with adjusted analyses confirming the protective effect of LDAS on fracture risk.
- * However, achieving LDAS did not show a significant correlation with changes in bone mineral density (BMD), indicating that while LDAS helps reduce fracture risk, it may not improve bone density itself.
Background: Acute fetal distress (AFD) is a condition that requires timely diagnosis because it generates hypoxia, acidosis, and even intrauterine death. This study aimed to determine lactate and pH values in the umbilical cord in full-term newborns (NBs) with a history of AFD.
Methods: We conducted a cross-sectional study in full-term NBs of mothers with at least one perinatal, neonatal, or gasometric AFD antecedent.
The Systemic Lupus International Clinics (SLICC)-Frailty Index (FI) is associated with adverse outcomes in systemic lupus erythematosus (SLE). However, to our knowledge, its association with bone mineral density (BMD) and vertebral fractures (VF), has not been investigated using a standardized methods. Our aim was to evaluate the relationship between frailty assessed by SLICC-FI, and BMD and VF in Mestizo women with SLE.
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- - The study examined how the COVID-19 pandemic influenced mortality rates in patients with systemic autoimmune rheumatic diseases (SARD) in Mexico by analyzing national data from 2010 to 2021.
- - It found that while the age-standardized mortality rate (ASMR) for SARD rose significantly pre-pandemic, it dropped during the pandemic, with actual mortality rates for 2020 and 2021 being lower than predicted for most SARD cases.
- - However, systemic lupus erythematosus (SLE) in the Southern region showed an increase in observed mortality rates that exceeded the predicted values, though no differences were noted based on sex or age groups in the overall data.
The aims of this study were in systemic lupus erythematosus (SLE) patients: 1) to compare the metabolomic profile of insulin resistance (IR) with controls and 2) to correlate the metabolomic profile with other IR surrogates and SLE disease variables and vitamin levels. In this cross-sectional study, serum samples were collected from women with SLE (n=64) and gender- and age-matched controls (n=71), which were not diabetic. Serum metabolomic profiling was performed using UPLC-MS-MS (Quantse score).
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- Mexico experienced high COVID-19 mortality rates, particularly in adults under 65, with over half of reported deaths occurring in this age group, potentially due to demographics and metabolic diseases.
- A study of 245 hospitalized COVID-19 patients revealed a case fatality rate (CFR) of 35.51%, with significant mortality linked to pre-existing conditions like chronic kidney disease and diabetes.
- The research suggested that an imbalance in immune response and specific inflammatory markers at day 7 post-admission could help identify individuals at high risk for severe outcomes, proposing a predictive tool for early intervention in vulnerable populations.
Article Synopsis
- This systematic review evaluated the adherence of machine learning (ML) applications in diagnosing and predicting systemic lupus erythematosus (SLE) using the TRIPOD reporting guidelines.
- Out of 45 analyzed studies, only 17% to 67% of required reporting standards were met, with notable gaps in essential areas like model performance, blinding of predictors, and handling missing data.
- The overall conclusion suggests that current reporting practices for ML-based models in SLE are inadequate, highlighting the need for improved transparency and consistency in research reporting.
Article Synopsis
- Hospitalizations for systemic lupus erythematosus (SLE) in Mexico from 2000 to 2019 totaled 17,081, predominantly affecting females (87.6%) and individuals aged 15-44 years (87%).
- The age-standardized hospitalization rate increased from 0.38 to 0.65 per 100,000 persons from 2000 to 2019, with a notable rise until 2011, followed by a decline from 2011 to 2019.
- Despite the overall increase, the length of hospital stays and inpatient mortality rates decreased from 2000 to 2019, indicating improvements in patient care.
Background: Patients with systemic lupus erythematosus (SLE) have an increased cardiovascular (CV) risk. Insulin resistance (IR), which is higher in patients with SLE, adversely impacts left ventricular (LV) remodeling and function. The aims were to determine LV dysfunction and evaluate the influence of potential risk factors on subclinical LV dysfunction in women with SLE, including IR.
View Article and Find Full Text PDFInsulin Resistance and Diabetes Mellitus in Patients with Systemic Lupus Erythematosus.
Endocr Metab Immune Disord Drug Targets
May 2023
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by damage to multiple systems and a higher risk of cardiovascular disease. In addition, several studies have found that insulin resistance (IR) is more prevalent in SLE patients than controls, increasing the risk of prediabetes, type 2 diabetes mellitus (T2DM) and morbidity. The objective of this review article was to summarize the most relevant evidence about the relationship among IR, T2DM and SLE, including the effects of proinflammatory states, acute-phase proteins, pro-inflammatory cytokines, and pharmacological SLE treatment.
View Article and Find Full Text PDFBackground: Leukemia is the most frequent cancer in children and adolescents, and it has a high prevalence of depression and anxiety which deteriorates the quality of life related to health. The symptoms of depression and anxiety may go unnoticed by the physician as a normal response during cancer treatment.
Objective: To determine the prevalence of depression, anxiety and health-related quality of life in pediatric patients with leukemia.
Objective: To investigate national temporal trends over time in mortality rates in patients with systemic sclerosis (SSc) in Mexico between 1998 and 2017.
Methods: Deaths between 1998 and 2017 were extracted from General Board of Health Information (DGIS) Open Access datasets. 2We identified all persons aged ≥15 years with a diagnosis of SSc (ICD-10 code M34).
[Influence of risk factors on mortality from COVID-19].
Rev Med Inst Mex Seguro Soc
July 2022
Article Synopsis
- A study was conducted to identify key risk factors influencing COVID-19 mortality, focusing on various health conditions and demographics.
- The study involved 1,190 patients, comparing those who died from COVID-19 to those who survived, analyzing factors like age, gender, and pre-existing conditions.
- Results indicated that the male gender does not significantly impact COVID-19 mortality, but factors such as being over 60, having high blood pressure, diabetes, and obesity do increase the risk of death.