Publications by authors named "Sobstyl J"

Despite the unequivocal medical and social advantages of introducing vaccines against the novel coronavirus SARS-CoV-2, there were also some concerns regarding possible post-vaccination adverse events. Most of these are mild. But in rare cases, severe neurological symptoms including ischaemic stroke, intracranial haemorrhage (ICH), cerebral venous and sinus thrombosis (CVT), and thrombosis with thrombocytopenia (TTS) have been observed.

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Aquaporins (AQPs), particularly AQP4, play a crucial role in regulating fluid dynamics in the brain, impacting the development and resolution of edema following traumatic brain injury (TBI). This review examines the alterations in AQP expression and localization post-injury, exploring their effects on brain edema and overall injury outcomes. We discuss the underlying molecular mechanisms regulating AQP expression, highlighting potential therapeutic strategies to modulate AQP function.

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Purpose: To assess the immediate efficacy of distinct embolisation devices in the endovascular treatment of pulmonary arteriovenous malformations as well as to identify and analyse the possible determinants of the technical success of the procedure.

Material And Methods: Prospective analysis of 16 consecutive patients was carried out, who underwent transcatheter endovascular embolisation therapy for pulmonary arteriovenous malformations between 2005 and 2017. Pre- and post-procedural angiography studies were implemented to confirm the diagnosis and to evaluate the technical success defined as the complete occlusion of the feeding artery.

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Purpose: In the present study, the effectiveness and safety of minimally invasive percutaneous extraction of residual post-cholecystectomy gallstones through the T-tube tract were assessed.

Material And Methods: Between 2000 and 2015, 12 patients (seven women and five men, mean age 78 ± 8 years) after open cholecystectomy with common bile duct exploration and T-tube drainage underwent percutaneous extraction of residual gallstones through the T-tube tract.

Results: The intervention was successful in 92% (11/12).

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INTRODUCTION Endovascular treatment of abdominal aortic aneurysms (AAAs) constitutes an alternative to the classic surgical approach. The procedure may be associated with specific complications, including persistent flow within the aneurysm sac, otherwise known as endoleak. OBJECTIVES The aim of the study was to assess the utility of ultrasound contrast agents in the diagnosis of endoleaks after endovascular AAA repair.

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Renal artery pseudoaneurysms and arteriovenous fistulae most often occur as an iatrogenic complication. The article discusses a case of a patient diagnosed with an arteriovenous fistula and a pseudoaneurysm. A 64-year-old woman was admitted to the hospital due to nonspecific pain in the lumbar region.

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External injuries are one of the common reasons for reporting to hospital emergency departments. Peripheral vascular injuries occur in up to about 25% of upper and lower extremity injury cases. Arteriovenous fistula is a type of arterial injury.

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Aim Of The Study: The aim of this study is to assess the prevalence and evolution of perirenal fluid collections in a group of 488 patients who have undergone kidney transplantation.

Material And Methods: Sonographic documentation of 488 deceased-donor kidney recipients was evaluated for the prevalence of perirenal fluid collections and their evolution in time, depending on selected demographic features of the patients, time of detection, initial dimensions and precise position of the collection relative to the kidney and the location of the transplanted organ in the right or left iliac fossa. The collected data were used for statistical analysis to determine the strength of the potential relationships.

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Aim: The aim of the study was to assess patient selection for embolization of varicoceles based on ultrasonography. An additional objective of the work was to evaluate the results of endovascular treatment.

Material And Methods: From January 2015 till August 2017, 53 patients with varicoceles diagnosed in an ultrasound examination underwent endovascular treatment in the Department of Interventional Radiology and Neuroradiology in Lublin, Poland.

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Aim: The purpose of this paper was to evaluate the efficacy of ultrasound-guided percutaneous thrombin injection as a treatment method for arterial access site pseudoaneurysm.

Materials And Methods: A total of 148 patients with iatrogenic arterial access site pseudoaneurysms were treated in the Department of Interventional Radiology and Neuroradiology, Medical University of Lublin. Of those, 142 pseudoaneurysms were located in the common femoral artery, 3 in the brachial artery and the remaining 3 in the radial artery.

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An urban heat island (UHI) is a climate phenomenon that results in an increased air temperature in cities when compared to their rural surroundings. In this Letter, the dependence of an UHI on urban geometry is studied. Multiyear urban-rural temperature differences and building footprints data combined with a heat radiation scaling model are used to demonstrate for more than 50 cities worldwide that city texture-measured by a building distribution function and the sky view factor-explains city-to-city variations in nocturnal UHIs.

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More than 44% of building energy consumption in the USA is used for space heating and cooling, and this accounts for 20% of national CO2emissions. This prompts the need to identify among the 130 million households in the USA those with the greatest energy-saving potential and the associated costs of the path to reach that goal. Whereas current solutions address this problem by analysing each building in detail, we herein reduce the dimensionality of the problem by simplifying the calculations of energy losses in buildings.

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Purpose: Many studies indicate an inverse relationship between stromal-derived factor-1 alpha (SDF-1 alpha), a chemokine, and coronary risk factors. Moreover, SDF-1 alpha is crucial in neoangiogenesis and in the mobilization and homing of endothelial progenitor cells to the ischemic coronary vessels. Numerous studies indicate that circulating sex hormones are associated with atherogenesis during male aging.

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Unlabelled: Both environmental and genetic factors play an important role in the pathogenesis of coronary artery disease. In view of angiotensin-converting enzyme (ACE) role in physiology and pathology and benefits of ACE-inhibitors therapy, the gene coding this protein meets criteria for candidate gene for the susceptibility to cardiovascular disease including myocardial infarction. The goal of our research was to assess the association of ACE gene I/D polymorphism with myocardial infarction in Polish population regarding different variables related to the disease (smoking, concomitant hypertension, obesity, plasma cholesterol level and family history).

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The aim of this study was the assessment of the association of human insulin receptor gene Nsil polymorphism with myocardial infarction in 100 patients and 140 healthy individuals. The polymorphism was studied using polymerase chain reaction. An association was found between N2 allele and myocardial infarction, particularly in patients with normal body weight and/or with positive family history.

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The aim of this study was an assessment of association of human endothelial nitric oxide synthase gene Ban II polymorphism with the myocardial infarction in 178 patients and 136 healthy individuals. These polymorphism were studied using polymerase chain reaction (PCR) and Ban II restriction fragment length polymorphism (RFLP). It was found that TT and GT genotypes and allele T were associated with myocardial infarction patients under 50 years.

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Background: Diabetes mellitus type 2 results from a complex of hereditary and environmental factors. Genes encoding elements of the G-protein system are candidate genes in hypertension and obesity. Since insulin uses G-sensitive mechanisms to enhance tissue glucose uptake and vasodilatation, the GNB3 gene may be a candidate gene in type 2 diabetes.

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Hyperhomocysteinemia is recognised as a risk factor of ischaemic heart disease and vascular complications of arterial hypertension. Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism is associated with hyperhomocysteinaemia. The aim of the study was the assessment of an association of the above polymorphism with type 2 diabetes with special attention to myocardial infarction and arterial hypertension accompanying diabetes.

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Background: The angiotensin-converting enzyme gene and the angiotensin II type 1 receptor gene meet the criteria for candidate genes in the pathogenesis of essential hypertension. The aim of this study was to assess the possible association between polymorphisms of these genes and essential hypertension in a Polish population, to evaluate them as possible genetic markers of susceptibility to hypertension, and to search for interaction between the two polymorphisms.

Material And Methods: The insertion/deletion polymorphism at the angiotensin-converting enzyme gene locus and the A1166C polymorphism at the angiotensin II type 1 receptor gene locus were detected using the polymerase chain reaction and restriction fragment length methods.

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Introduction: The aim of this study was to investigate the association between Pvu II and Msp I polymorphisms of the human apolipoprotein B gene and risk of myocardial infarction in 90 survivors of myocardial infarction. Apolipoprotein B is important in the metabolism of lipoproteins and there is an evidence suggesting that this apolipoprotein plays a central role in atherogenesis. Some polymorphisms in the apolipoprotein B gene are associated with peripheral arterial disease, coronary artery disease and risk of myocardial infarction.

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