Atypical Presentation of COVID-19 in Older Adults: A Scoping Review.

Background: COVID-19 has currently well-described signs and symptoms. However, older adults often present with an atypical condition, which can confuse and delay diagnosis and treatment.

Summary: A scoping review was performed according to Joanna Briggs Institute methodology and prepared using the PRISMA-ScR.

Soil greenhouse gas emissions and grazing management in northern temperate grasslands.

Adaptive multi-paddock (AMP) grazing, a grazing system in which individual paddocks are grazed for a short duration at a high stock density and followed by a long rest period, is claimed to be an effective tool to sustainably manage and improve grasslands and enhance their ecosystem services. However, whether AMP grazing is superior to conventional grazing (n-AMP) in reducing soil greenhouse gas (GHG) emissions is unclear. Here, we measured CO, CH, and NO fluxes between August 2017 and August 2019 in 12 pairs of AMP vs.

Prolactin and human weight disturbances: A puzzling and neglected association.

Weight gain at the outset of prolactinomas in many women is well documented. Yet, this symptom is absent from the clinical descriptions of the disease in textbooks and reviews. This omission is almost certainly due to the absence of a physiological explanation for the phenomenon, as prolactin is not a recognized fat promoting hormone.

Infection by Mycoplasma spp., feline immunodeficiency virus and feline leukemia virus in cats from an area endemic for visceral leishmaniasis.

Background: Visceral leishmaniasis (VL) has been increasingly recognized in cats living in areas endemic for the disease. Co-infection with Leishmania infantum and other infectious agents is well established in dogs. However, for cats, data on co-infections with L.

The Calcium/Phosphorus Homeostasis in Chronic Kidney Disease: From Clinical Epidemiology to Pathophysiology.

Introduction: A simple data filtering process together with some basic concepts of control theory applied to electronically stored clinical data were used to identify some of the pathophysiological mechanisms underlying the perturbations of the calcium/phosphorus homeostasis in chronic kidney disease.

Material And Methods: Retrospective data (a set per patient of serum single value concentrations of creatinine, calcium, phosphorus, parathormone, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D) from 2507 patients with stable chronic kidney disease not on renal replacement therapy were studied. The variables were paired and subjected sequentially to a moving average and partioned into frequency classes.

The effect of mechanical loading on the cusp defection of premolars restored with direct and indirect techniques.

Aim: This study assessed the effect of fatigue load cycling on human premolars restored with MOD restorations (direct and indirect approaches) on cuspal defection, compared to intact teeth (unprepared) and unrestored teeth with an inlay preparation.

Materials And Methods: MOD inlay preparations were performed on sixty premolars with their roots embedded in acrylic resin. These teeth were divided into six groups (n = 10): (1) intact teeth; (2) unrestored and prepared teeth; (3) teeth restored with direct composite resin; (4) teeth restored with an indirect composite resin; (5) teeth restored with injected ceramic inlays (IPS Empress 2 (Ivoclar); (6) teeth restored with CAD/CAM inlays made of feldspathic ceramic (Vita Mark II).

Influence of cone beam CT enhancement filters on diagnosis ability of longitudinal root fractures.

Objectives: To determine whether cone beam CT (CBCT) enhancement filters influence the diagnosis of longitudinal root fractures.

Methods: 40 extracted human posterior teeth were endodontically prepared, and fractures with no separation of fragments were made in 20 teeth of this sample. The teeth were placed in a dry mandible and scanned using a Classic i-CAT® CBCT device (Imaging Sciences International, Inc.

Coinfection of Leishmania chagasi with Toxoplasma gondii, Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FeLV) in cats from an endemic area of zoonotic visceral leishmaniasis.

The aim of the present study was to determine the coinfection of Leishmania sp. with Toxoplasma gondii, Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FeLV) in a population of cats from an endemic area for zoonotic visceral leishmaniasis. An overall 66/302 (21.

Dimensional change of elastomeric materials after immersion in disinfectant solutions for different times.

Aim: The aim of this study was to evaluate the influence of immersion period in two disinfectant solutions on dimensional change of four elastomeric impression materials.

Materials And Methods: Four representative materials of each class of elastomers: Xantopren (polydimethylsiloxane-PDS), Express (polyvinyl siloxane-PVS); Permlastic (polysulfide- PS) and Soft Impregum (polyether-EP) were mixed according to manufacturers' instructions and then inserted into a metal matrix prepared according to the specification of ISO 4823. The molds were removed from the matrix after 7 minutes and immersed in disinfectant solutions (sodium hypochlorite 0.

Effects of horizontal misfit and bar framework material on the stress distribution of an overdenture-retaining bar system: a 3D finite element analysis.

Purpose: To evaluate the influence of horizontal misfit change and bar framework material on the distribution of static stresses in an overdenture-retaining bar system using finite element (FE) analysis.

Materials And Methods: A 3D FE model was created including two titanium implants and a bar framework placed in the anterior part of a severely resorbed jaw. The model set was exported to mechanical simulation software, where horizontal displacement (10, 50, 100, and 200 μm) was applied simulating the settling of the framework, which suffered shrinkage during laboratory procedures.

Paternal deprivation prior to adolescence and vulnerability to pituitary adenomas.

It has been reported that women with prolactinoma were exposed, early in life, to an environment characterized by an absent or violent father. The present study was designed to evaluate whether paternal absence or violent paternal behavior were more prevalent in patients with pituitary adenomas (prolactinoma, acromegaly, non-secreting adenoma and Cushing's disease) compared to a control population. We conducted an observational case-control multicenter study.

Bond strength of fiber posts in different root thirds using resin cement.

Purpose: The aim of the study was to assess the in vitro bond strength (BS) of glass fiber posts (GF) and carbon fiber posts (CF) in the cervical, middle, and apical thirds of root canals cemented with RelyX-Unicem (RX) and Cement-Post (CP).

Materials And Methods: Forty maxillary canines were divided into 4 groups (n = 10) according to the cement and post used: group 1: GF and RX; group 2: CF and RX; group 3: GF and CP; group 4: CF and CP. The push-out test was applied in the cervical, middle and apical thirds of each specimen to assess bond strength of the cement/post complex to the root canal wall.

Identification of de novo germline mutations in the HRPT2 gene in two apparently sporadic cases with challenging parathyroid tumor diagnoses.

The diagnosis of parathyroid carcinomas is often difficult. HRPT2 mutations have been identified in familial [hyperparathyroidism-jaw tumor (HPT-JT) syndrome] and sporadic parathyroid carcinomas, supporting that HRPT2 mutations may confer a malignant potential to parathyroid tumors. In this study, we report the clinical, histopathological, and genetic investigation of two unrelated cases, whom had apparently sporadic malignant parathyroid tumors, initially diagnosed as adenomas.

Leishmania chagasi infection in cats with dermatologic lesions from an endemic area of visceral leishmaniosis in Brazil.

Although dogs are considered the main domestic reservoirs for Visceral Leishmaniosis (VL), which is caused in the Americas by Leishmania chagasi, infected cats have also been recently found in endemic areas of several countries and became a public health concern. Accordingly, the purpose of this study was to evaluate cats with dermatologic lesions from an endemic area of VL and the natural infection of L. chagasi.

Use of crude, FML and rK39 antigens in ELISA to detect anti-Leishmania spp. antibodies in Felis catus.

Visceral leishmaniasis is a disease caused by Leishmania (Leishmania) chagasi and represents a serious public health problem. The dog is the main urban reservoir of the disease; however, investigations regarding the occurrence and epidemiological importance of leishmaniasis in cats have recently been initiated. This study aimed to detect cats seropositive for Leishmania spp.

Clinical and genetic characterization of Portuguese patients with pseudohypoparathyroidism type Ib.

Patients with pseudohypoparathyroidism type Ib (PHP-Ib) present hypocalcemia and hyperphosphatemia, as a consequence of a resistance to PTH action, through its G-protein-coupled receptor, in the renal tubules. This resistance results from tissue-specific silencing of the G-protein alpha-subunit (G(s)α), due to imprinting disruption of its encoding locus--GNAS. In familial PHP-Ib, maternally inherited deletions at the STX16 gene are associated to a regional GNAS methylation defect.

Effect of light-curing method and indirect veneering materials on the Knoop hardness of a resin cement.

This study evaluated the Knoop hardness of a dual-cured resin cement (Rely-X ARC) activated solely by chemical reaction (control group) or by chemical / physical mode, light-cured through a 1.5 mm thick ceramic (HeraCeram) or composite (Artglass) disc. Light curing was carried out using conventional halogen light (XL2500) for 40 s (QTH); light emitting diodes (Ultrablue Is) for 40 s (LED); and Xenon plasma arc (Apollo 95E) for 3 s (PAC).

Fracture loads of all-ceramic crowns under wet and dry fatigue conditions.

Purpose: The aim of this study was to test the hypothesis that fracture loads of fatigued dental ceramic crowns are affected by testing environment and luting cement.

Materials And Methods: One hundred and eighty crowns were prepared from bovine teeth using a lathe. Ceramic crowns were prepared from three types of ceramic systems: an alumina-infiltrated ceramic, a lithia-disilicate-based glass ceramic, and a leucite-reinforced ceramic.

Dimensional accuracy of upper complete denture bases: the effect of metallic flask closure methods.

Objectives: To verify the dimensional accuracy of upper complete denture bases under the effect of different methods of metallic flask closure.

Materials And Methods: Wax record bases were assigned to six groups: 1-2: traditional clamp; 3-4: RS system; and 5-6: flask with screws. Flasks were immediately polymerised or bench stored for 6 h prior to polymerisation.

Mapping a new familial thyroid epithelial neoplasia susceptibility locus to chromosome 8p23.1-p22 by high-density single-nucleotide polymorphism genome-wide linkage analysis.

Context: Familial nonmedullary thyroid carcinoma (FNMTC) accounts for approximately 5% of all thyroid tumors. Genetic mapping studies have identified four different chromosomal regions predisposing to FNMTC: fPTC/PRN (1p13.2-1q22), NMTC1 (2q21), MNG1 (14q32), and TCO (19p13.

Expression of iodine metabolism genes in human thyroid tissues: evidence for age and BRAFV600E mutation dependency.

Context: Children present a higher susceptibility to developing thyroid cancer after radioiodine exposure and also a higher frequency of functional metastases than adults.

Objective: To assess the mRNA expression of the sodium/iodide (Na(+)/I(-)) symporter (NIS), the Pendred syndrome gene (PDS), thyroperoxidase (TPO), thyroglobulin (Tg) and TSH receptor (TSH-R) in normal thyroid tissues (NTTs) and papillary thyroid carcinomas (PTCs) among different age groups.

Methods: Analysis included 59 samples: 21 NTTs and 38 PTCs, of which 21 were the classic type (CPTC) and 17 the follicular variant (FVPTC).

The influence of 30-day-old Streptococcus mutans biofilm on the surface of esthetic restorative materials--an in vitro study.

Objective: To evaluate the effects of Streptococcus mutans biofilm/restorative materials interaction on surface roughness, hardness and morphology of materials tested.

Methods: Empress 2 (E2), Filtek Supreme (FS), Vitremer (V) and Ketac Molar Easymix (KM) were tested. Twenty-five disks of each material were made and divided into three storage groups: (1) 100% relative humidity (n=5); (2) growth medium (BHI and 1% sucrose) (n=5); (3) S.

NaOCl effects on primary and permanent pulp chamber dentin.

Objectives: The dentin quality of primary and permanent pulp chamber was inspected by Fourier-transformed Raman spectroscopy (FT-Raman) and scanning electron microscopy (SEM). Fragments of pulp chamber dentin were obtained from 20 human molar crowns (primary and permanent).

Methods: The fragments were assigned to 8 groups (n=5)-Primary teeth: G1, pulp chamber dentin; G2, pulp chamber dentin irrigated with NaOCl 1% (30 min); G3, pulp chamber dentin irrigated with NaOCl 1% (30 min) and etched by 35% phosphoric acid; G4, pulp chamber dentin etched by 35% phosphoric acid.