Topical Therapies for Periorbital Dyschromia: A 30-Year Review of the Literature.

Background: Periorbital dyschromia (POD) is a prevalent dermatologic problem with multifactorial etiology, making treatment outcomes inconsistent and unclear.

Objective: To evaluate and compose a comprehensive review of topical ingredients proven to be effective in the treatment of POD.

Materials And Methods: Scopus, PubMed, and OVID databases were searched in a span of 30 years through December 31, 2023, to identify articles with original findings of topical therapies for the treatment of POD.

School students' burdens and resources after 2 years of COVID-19 in Austria: a qualitative study using content analysis.

Introduction: The mental health of young people has been severely affected by the COVID-19 pandemic and the measures associated with it. Mental health symptoms increased across various domains during the pandemic and subjective wellbeing decreased.

Methods: This study examined the burdens and resources of Austrian school students ( = 16.

Effect of shell spacing on mechanical behavior of multi-span soil-steel composite structure.

This study analyses the effect of lateral shells on central shell at a different spacing in a multi-span soil-steel composite structure subjected to quasi-static moving loads. The displacements and internal forces of the central shell during consecutive truck passages over the structure are investigated by finite element (FE) analysis. Field measurements from a site in Niemcza, Poland, are used to calibrate input parameters.

A comprehensive computer aided approach to design of earthen dams of dry flood-control reservoirs.

A generalized, comprehensive approach to geotechnical design of earthen dams of dry flood-control reservoirs is developed. It consists of three steps:•In Step 1 three-dimensional (3D) model of terrain and dam subsoil is created. The arrangement of geotechnical layers is reconstructed based on results of geotechnical investigation using geostatistical interpolation, namely, kriging.

Understanding ecological response to physical characteristics in side channels of a large floodplain-river ecosystem.

Side channels in large floodplain rivers serve a variety of important ecological roles, particularly in reaches where habitat conditions have been degraded or diminished. We developed hypotheses regarding side channel ecological structure whereby we expected species richness of young-of-year fishes to generally be higher in shallower, more physically heterogeneous side channels with lower velocities, with differences based on reproductive guild. We also hypothesized species richness of adult fishes to be higher in side channels with greater heterogeneity that could support diverse foraging resources and provide refugia during extreme flow conditions.

Methods of Protecting Buildings against HPM Radiation-A Review of Materials Absorbing the Energy of Electromagnetic Waves.

The pulsed high power microwave (HPM) technology has been developed worldwide for over 20 years. The sources of HPM pulses are a weapon of mass destruction. They pose danger especially to computer and telecommunications equipment and systems, both the military and civilian ones.

Assessment of the Condition of Wharf Timber Sheet Wall Material by Means of Selected Non-Destructive Methods.

This paper presents an assessment of the condition of wood coming from a wharf timber sheet wall after 70 years of service in a (sea) water environment. Samples taken from the structure's different zones, i.e.

Application of Nanoindentation and 2D and 3D Imaging to Characterise Selected Features of the Internal Microstructure of Spun Concrete.

The spinning of concrete is a process in which concrete mixture is moulded and compacted under the action of the centrifugal force arising during the fast rotational motion of the mould around its longitudinal axis. As a result of the spinning of the liquid concrete mixture, an element annular in cross section, characterised by an inhomogeneous layered wall structure, is produced. The heavier constituents tend towards the cross-section wall's outer side, while the lighter components tend towards its inner side.

Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration.

Background: Microglia reactivity is a hallmark of retinal degenerations and overwhelming microglial responses contribute to photoreceptor death. Minocycline, a semi-synthetic tetracycline analog, has potent anti-inflammatory and neuroprotective effects. Here, we investigated how minocycline affects microglia in vitro and studied its immuno-modulatory properties in a mouse model of acute retinal degeneration using bright white light exposure.

Changing attitudes about self-injury prevention management: lessons learned.

In the behavioral health environment, nurses often use continuous staff monitoring and, at times, physical restraints, to manage the severity of patients' self-injury. Both options put staff in control, are the most restrictive in nature, and can be financially draining on the hospital's budget. This can result in negative reactions by both patients and staff.

Biofiltration of paint solvent mixtures in two reactor types: overloading by hydrophobic components.

Steady-state performance characteristics of a trickle bed reactor (TBR) and a biofilter (BF) in loading experiments with increasing toluene/xylenes inlet concentrations while maintaining a constant loading rate of hydrophilic components (methyl ethyl and methyl isobutyl ketones, acetone, and n-butyl acetate) of 4 g m⁻³ h⁻¹ were evaluated and compared, along with the systems' dynamic responses. At the same combined substrate loading of 55 g m⁻³ h⁻¹ for both reactors, the TBR achieved more than 1.5 times higher overall removal efficiency (RE(W)) than the BF.

[Pneumosurgery in the management of colorectal carcinomas].

Objective: Surgically solved lung involvement in patients after surgery of colorectal cancer.

Materials And Methods: Altogether 15 patients, 9 men (median age in the time of lung diagnosis 67 years) and 6 women (median age 59 years) underwent classical open pulmonary surgery during 2003-2008 years from the follow-up cohort of 836 persons after operation due to colorectal cancer in the time period of 1996-2008 years. The indication for lung surgery: solitary pulmonary lesion.

[Complications in patients undergoing pulmonary oncological surgery].

Aim: A survey evaluating incidence and risk factors of complications in persons underwent complete open lung resection because of primary or secondary lung malignancy.

Material And Methods: Retrospective study of 189 open surgery procedures in 128 males and 61 females, mean age males 61 years (range 21-78), females 64 years (range 33-80) during a five-years period (2003-2007). Data processing and analysis were performed with the statistical software system Statistica and compared by parametres odds ratio a chi2 test.

Ampullary tumours (ampullomas) in the elderly--an interdisciplinary problem.

Background & Objectives: Ampullary cancer is one of the periampullary tumours with better prognosis, but relapses occur early in some patients. This study was carried out to assess whether pancreatoduodenectomy (PDE, Whipple operation) could be a safe therapeutic procedure for elderly patients with periampullary tumours.

Methods: Between 2005 and 2007, 19 patients (12 male, 7 female) aged over 65 yr (range 66 and 83 yr) with diagnosis of ampulloma were operated.

Nonlinear selection and the evolution of variances and covariances for continuous characters in an anole.

The pattern of genetic variances and covariances among characters, summarized in the additive genetic variance-covariance matrix, G, determines how a population will respond to linear natural selection. However, G itself also evolves in response to selection. In particular, we expect that, over time, G will evolve correspondence with the pattern of multivariate nonlinear natural selection.

Hydrogen sulfide removal from air by Acidithiobacillus thiooxidans in a trickle bed reactor.

A strain of Acidithiobacillus thiooxidans immobilized in polyurethane foam was utilized for H(2)S removal in a bench-scale trickle-bed reactor, testing the limits of acidity and SO(4) (2-) accumulation. The use of this acidophilic strain resulted in remarkable stability in the performance of the system. The reactor maintained a >98-99 % H(2)S removal efficiency for c of up to 66 ppmv and empty bed residence time View Article and Find Full Text PDF

Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation.

The previously constructed strain Corynebacterium glutamicumilvNM13 with acetohydroxy acid synthase, resistant to inhibition by all three branched-chain amino acids (L-valine, L-isoleucine and L-leucine), was used as a basis to develop a new type of valine producer by genetic engineering. The main strategy was to modulate expression of the genes involved in the biosynthesis of branched-chain amino acids. The activity of the promoters P-ilvD (dihydroxyacid dehydratase) and P-ilvE (transaminase) was up-modulated and the activity of the promoters P-ilvA (threonine deaminase) and P-leuA (isopropylmalate synthase) was down-modulated by site-directed mutagenesis.

Relationship between volatile odorous substances and production of avermectins by Streptomyces avermitilis.

The time course of production of odorous compounds, i.e. geosmin and oxolones, and of avermectins was determined during the cultivation of S.

Use of the industrial yeast Candida utilis for cadmium sorption.

The sorption ability of Candida utilis biomass for cadmium ions with accumulating competence of dried cells and cells in alginate was compared. After an optimization of process conditions (pH 5.5, biomass concentration 1 g/L and c0 50 mg/L), the cadmium sorption capacity of dried yeast biomass was perceptibly higher than that of the other tested adsorbents.

Removal of copper ions from dilute solutions by Streptomyces noursei mycelium. Comparison with yeast biomass.

Sorption properties of Streptomyces noursei mycelium for copper ions were compared with the accumulation competence of dried and native yeast (Candida utilis) biomass. The copper sorption capacity of S. noursei after optimization was found to be higher than that of the two other adsorbents (dried yeast biomass 82 %, native Candida cells 48 % of the sorption capacity of the S.

Continuous aerobic phenol degradation by defined mixed immobilized culture in packed bed reactors.

A defined mixed culture of Pseudomonas putida, Commamonas testosteroni and Candida tropicalis was immobilized by adsorption on polyurethane foam, cocoa-fibers, expanded slate and sintered glass. Packed bed reactors were used for long-term continuous phenol biodegradations. Loading experiments were done to study the impact of the following parameters: (1) hydraulic retention time, (2) dissolved oxygen concentration, and (3) elimination of the oxygen limitation.

Physiological dendrogram of Claviceps spp. based on sucrose metabolism in submerged cultures and its comparison with phylogenetic tree.

Sixteen isolates of Claviceps spp. were analyzed for the production of polysaccharides, oligosaccharides, and sucrose metabolism under conditions of submerged fermentation. Physiological markers calculated by the Verhulst-Pearl law were used for hierarchical cluster analysis.