[Thyroxine caused modulation of dexamethasone effects on the skeletal muscle of white rats].

Experiments in situ on mature white female rats performed with the use of electrophysiological methods allowed to investigate the modulatory influence of thyroxin at the dose which does not cause the signs of hyperthyroidism (10 mkg/ kg), upon the manifestation of the dexamethasone effects on the functional state of the anterior tibial muscle. It has been established that the chronic isolated application of dexamethasone was accompanied by reduction of the amplitude ofmuscle contraction (by 29.7-59.

[Modulation of the effects of dexamethasone in rat skeletal muscle by testosterone].

In experiments on young females white rats by means of methods of electromyography and ergography we investigated the efficiency of a testosterone-propionate for smoothing of negative effects of dexamethasone on skeletal muscle. It has been established that the chronic injection of dexamethasone causes the decreasing of amplitude of contraction of forward tibial muscle on 29.7-59.

[Characterization of the latent periods of excitation and shortening of anterior tibial muscle of white rats depending on the blood level of triiodothyronine].

In experiments in situ it was shown an expressed negative correlation between the duration of latent periods of excitation and contraction of the anterior tibial muscle of white rats and the blood level of free triiodothyronine. The difference in mean values of latent periods at starting and final points of scale of physiological fluctuations of triiodothyronine level amounted 15.5% and 37.

[Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats].

The present work was devoted to the comparative analysis of influence of chronic administration of 5-HT(2B/2C) receptors agonist - m-CPP (0,5 mg/kg, i.p.) and 5-HT(2A/2C) receptors antagonist - ketanserine (0,1 mg/kg, i.

[Effect of thyroidectomy on energetics of isometric muscle contraction in white rats].

The effect of thyroidactomia on parameters of energetics of isometric contractions of front shin--bone muscle of white rats is studied in in situ experiments. It is shown that experimental atiriosis lengthen considerably the latent period of muscle contractions (+95%) considerably reduce (in 5.5 times) the speed of it contraction in first phase of contraction act and also considerably increase the time (+37%), which necessery for developing maximum strength of contraction.

[The adrenergic reactions to isopropylnoradrenaline in white rats during the development of experimental hyperthyroidism].

In the experiments with white rats injected with atropin the condition of three types of physiological adrenergic reactions was studied (intravenous infusion of isopropylnoradrenaline at a rate of 2.0 micrograms/kg/min): chronotropic reaction of the heart, calorigenic and thermogenic reactions. Experimental hyperthyroidism was caused by subcutaneous injections of thriiodothyronine at a dose of 100 micrograms/kg a day.