Synthesis of Substituted 1,2,4-Triazole-3-Thione Nucleosides Using Purine Nucleoside Phosphorylase.

1,2,4-Triazole derivatives have a wide range of biological activities. The most well-known drug that contains 1,2,4-triazole as part of its structure is the nucleoside analogue ribavirin, an antiviral drug. Finding new nucleosides based on 1,2,4-triazole is a topical task.

Antimicrobial and Cytotoxic Activities of the Secondary Metabolites of Endophytic Fungi Isolated from the Medicinal Plant .

According to the World Health Organization, it is estimated that by 2050, drug-resistant infections could cause up to 10 million deaths annually. Therefore, finding a new generation of antibiotics is crucial. Natural compounds from endophytic fungi are considered a potential source of new-generation antibiotics.

A comparative study on chemical composition and antimicrobial activity of essential oils from three species from Uzbekistan.

Essential oils obtained from the aerial parts of and were determined using GC-FID and GC-MS methods. A total of 76 components were identified in the three species representing 97.12, 88.

Component composition of the extracts and essential oils from the , growing in Uzbekistan and their antimicrobial activity.

The volatile compounds of hexane, benzene extracts and essential oils (EOs) isolated by steam- and hydrodistillation methods from aerial part of were studied by GC-MS analysis. Seventeen components were found in the hexane and benzene extracts, among them palmitic acid (25.2 and 22.

Chemical composition, antimicrobial and antioxidant activities of the essential oils of three Uzbek Lamiaceae species.

The chemical composition of the essential oil from the aerial parts of three Lamiaceae species from Uzbekistan was investigated by GC-MS analysis. β-Linalool (26.6%), α-terpineol (10.