Doped magnetic nanoparticles: From synthesis to applied technological frontiers.

Doped magnetic nanoparticles (DMNPs) have become a fascinating class of nanomaterials with important implications in science and technology. The comprehensive review focuses on the synthetic methods, types of doping elements, distinctive properties, and extensive applications of DMNPs. The synthesis section highlights different methods, highlighting their benefits and drawbacks, such as chemical precipitation, co-precipitation, thermal breakdown, sol-gel, and other processes.

Development of novel FRET aptasensor based on the quenching ability of iron oxide-gold nanostars for the detection of aflatoxin M1.

Detecting Aflatoxin M1 (AFM1) in food products is crucial due to its high toxicity and health risks. This study introduced a fluorescence donor material using Rhodamine-B-Isothiocyanate (RBITC)-doped silica nanoparticles (RDSN) combined with iron oxide‑gold nanostars (IOGNS) as a quencher. The composite aptasensor (RDSN/IOGNS) served as a Förster Resonance Energy Transfer (FRET) nanoprobe for sensitive and selective AFM1 detection.

Fluorescent DNA-Silver nanoclusters in food safety detection: From synthesis to application.

In recent years, the conventional preparation of silver nanoclusters (AgNCs) has attracted much attention due to their ultra-small size, tunable fluorescence, easy-to-engineer, as well as biocompatible material. Moreover, its great affinity towards cytosine bases on single-stranded DNA has led to the construction of biosensors, especially aptamers, for a broad variety of applications in food safety and environmental protection. In past years, numerous researchers paid attention to the construction of AgNCs aptasensor.

Aptamer functionalized gold nanoclusters as an emerging nanoprobe in biosensing, diagnostic, catalysis and bioimaging.

DNA nanostructures, with their fascinating luminescent and detecting capabilities, provide a basis that can accommodate a wide range of applications. The unique electronic configurations, and physical and chemical properties of aptamer-assembled gold nanoclusters (apt-AuNCs) as a novel type of fluorophore have gradually piqued the interest of the scientific community. Bending DNA sequences and other templates/legends as a stabilizing agent with Au metal has produced an abundance of biosensors, along with catalytic and imaging properties.

Probiotics: mechanism of action, health benefits and their application in food industries.

Probiotics, like lactic acid bacteria, are non-pathogenic microbes that exert health benefits to the host when administered in adequate quantity. Currently, research is being conducted on the molecular events and applications of probiotics. The suggested mechanisms by which probiotics exert their action include; competitive exclusion of pathogens for adhesion sites, improvement of the intestinal mucosal barrier, gut immunomodulation, and neurotransmitter synthesis.

Universal Near-Infrared Fluorescent Nanoprobes for Detection and Real-Time Imaging of ATP in Real Food Samples, Living Cells, and Bacteria.

Adenosine triphosphate (ATP), an essential metabolite for active microorganisms to maintain life activities, has been widely regarded as a marker of cell activity and an indicator of microbial contamination. Herein, we designed two near-infrared (NIR) fluorescent nanoprobes named CYA@ZIF-90 and CYQ@ZIF-90 by encapsulating the NIR dye CYA/CYQ in ZIF-90 for the rapid detection of ATP. Between them, nanoprobe CYA@ZIF-90 can achieve higher NIR emission (702 nm) and rapid detection (2 min).

Cascade DNA Circuits Mediated CRISPR-Cas12a Fluorescent Aptasensor based on Multifunctional Fe O @hollow-TiO @MoS Nanochains for Tetracycline Determination.

Herein, for the first time, the CRISPR-Cas12a system is combined with aptamer, cascaded dynamic DNA network circuits, and Fe O @hollow-TiO @MoS nanochains (Fe O @h-TiO @MoS NCs) to construct an efficient sensing platform for tetracycline (TC) analysis. In this strategy, specific recognition of the target is transduced and amplified into H1-H2 duplexes containing the specific sequence of Cas12a-crRNA through an aptamer recognition module and the dual amplification dynamic DNA network. Subsequently, the obtained activated Cas12a protein non-specifically cleaves the adjacent reporter gene ssDNA-FAM to dissociate the FAM molecule from the quencher Fe O @h-TiO @MoS NCs, resulting in the recovery of the fluorescence signal and further signal amplification.

Novel metal enhanced dual-mode fluorometric and SERS aptasensor incorporating a heterostructure nanoassembly for ultrasensitive T-2 toxin detection.

Fluorescent gold (Au) nanostructures have emerged as burgeoning materials to fabricate nanomaterial assemblies which play a vital role in improving the detection sensitivity and specificity for various biomolecules. In this work, a fluorescence labelled (Rhodamine-B-Isothiocyanate) silica shell with Au metal core (AuNPs@PVP@RITC@SiO) and a graphene-Au nanostar nanocomposite (rGO-AuNS) are presented as a metal enhanced fluorescence (MEF) material and Raman signal enhancer, respectively. Their composite (AuNPs@PVP@RITC@SiONPs/rGO-AuNS) was employed as a dual-mode fluorescence (FL) and surface-enhanced Raman scattering (SERS) nanoprobe for selective and sensitive detection of T-2 toxin.

Effect of co-fermentation system with isolated new yeasts on soymilk: microbiological, physicochemical, rheological, aromatic, and sensory characterizations.

The beany flavor adversely influences consumer acceptance of soymilk (SM) products. Thus, in this work, the co-fermentation of isolated new yeasts (Kluyveromyces marxianus SP-1, Candida ethanolica ATW-1, and Pichia amenthionina Y) and Kluyveromyces marxianus K (a commercial yeast) along with an XPL-1 starter (including five strains of lactic acid bacteria (LAB)) was utilized to mend the beany flavor of fermented SM (FSM) beverages. Probiotic count, pH, titratable acidity, syneresis, water holding capacity, rheological characteristics, and sensory attributes were investigated.

Split aptamer acquisition mechanisms and current application in antibiotics detection: a short review.

Antibiotic contamination is becoming a prominent global issue. Therefore, sensitive, specific and simple technology is desirable the demand for antibiotics detection. Biosensors based on split aptamer has gradually attracted extensive attention for antibiotic detection due to its higher sensitivity, lower cost, false positive/negative avoidance and flexibility in sensor design.

Synthesis and characterization of cinnamic acid conjugated N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride derivatives: A hybrid flocculant with antibacterial activity.

The modified natural biopolymers, recognized as environmentally friendly flocculants, are gaining tremendous attention in the field of water treatment. In this study, a novel hybrid flocculant with antibacterial activity, cinnamic acid (CA) conjugated N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride (HTCC) derivative (HTCC-CA), was prepared via quaternary ammonium and amide reactions. The characterization, flocculation, and antibacterial activities were carried out to access the structural properties and potential application.

Research update of emergent gold nanoclusters: A reinforced approach towards evolution, synthesis mechanism and application.

Fluorescent biosensors and imaging devices have gained fervent consideration due to their prime functionality in biological. Among fluorescent nanomaterial (FNMs), the ultra-small gold nanoclusters (AuNCs) have gained promising attention with respect to extra-ordinary properties of bright fluorescence, economical synthesis, higher photostability, and biocompatibility, and deep tissue penetration. Therefore, the prior decades comprehended the revolutions in the field of real-time monitoring devices, nanotechnology-based biosensing, and bioimaging sensors.

Advances in sustainable approaches utilizing orange peel waste to produce highly value-added bioproducts.

Orange peel waste (OPW), a discarded part of orange fruit, is a rich source of essential constituents that can be transformed into highly value-added bioproducts. OPW is being generated in million tonnes globally and returns to the environment without complete benefit. Thus, a high volume of annually produced OPW in the industry requires effective valorization.

Kinetically modelled approach of xanthan production using different carbon sources: A study on molecular weight and rheological properties of xanthan.

The present study emphasizes improving the overall yield, productivity and quality of xanthan by Xanthomonas campestris using different carbon sources via optimizing the fermentation media and kinetic modelling work. After optimization, six carbon sources and one nitrogen source were selected for xanthan production in 5 L bioreactor. Kinetic modelling was applied to assess the experimental fermentation data and to check its influence on scale-up production.

Facile synthesis and antibacterial activity of geraniol conjugated chitosan oligosaccharide derivatives.

A new chitosan oligosaccharide derivative (COS-N-Ger), based on geraniol (Ger) modificated onto the NH position of chitosan oligosaccharide (COS) via a facile method, was prepared and employed to evaluate in vitro antibacterial activity. The structures of COS-N-Ger derivatives were confirmed by FT-IR, H, C NMR, and elemental analysis. The characterization results showed successful synthesis of derivatives and the degrees of substitution (DS) of COS-N-Ger1-3 were from 0.

Drug nanodelivery systems based on natural polysaccharides against different diseases.

Drug nanodelivery systems (DNDSs) are fascinated cargos to achieve outstanding therapeutic results of various drugs or natural bioactive compounds owing to their unique structures. The efficiency of several pharmaceutical drugs or natural bioactive ingredients is restricted because of their week bioavailability, poor bioaccessibility and pharmacokinetics after orally pathways. In order to handle such constraints, usage of native/natural polysaccharides (NPLS) in fabrication of DNDSs has gained more popularity in the arena of nanotechnology for controlled drug delivery to enhance safety, biocompatibility, better retention time, bioavailability, lower toxicity and enhanced permeability.

Selection of potential aptamers for specific growth stage detection of .

remains a threat to public health, and a sensitive detection method is a prerequisite due to its complicated diagnosis associated with slow growth. Recently, aptamer-based detection systems have played a vital role in the development of simple, rapid, sensitive, and specific detection methods. Herein, highly specific ssDNA aptamers were screened against at the different growth stages by whole cell-SELEX.

Xanthan-Curdlan nexus for synthesizing edible food packaging films.

In this study, we prepared a series of edible blend films of xanthan and curdlan by mixing different ratios of these two biopolymers. Characterization techniques like FTIR, XRD, TGA and SEM analysis were applied to investigate the newly formed films. Moreover, mechanical properties, moisture absorbance properties and water solubility of these films were also determined.

Photocatalysis and degradation products identification of deoxynivalenol in wheat using upconversion nanoparticles@TiO composite.

Deoxynivalenol (DON) is one of the most common contaminants of cereal grains. Efficient and environmental-friendly technology to eliminate DON is important for food safety and environmental protection. In this work, upconversion nanoparticles (UCNP) coated with titanium dioxide (TiO) photocatalysts were synthesized.

A comprehensive review on the prevalence, pathogenesis and detection of .

Food safety is imperative for a healthy life, but pathogens are still posing a significant life threat. "Yersiniosis" is caused by a pathogen named and is characterized by diarrheal, ileitis, and mesenteric lymphadenitis types of sicknesses. This neglected pathogen starts its pathogenic activity by colonizing inside the intestinal tract of the host upon the ingestion of contaminated food.

Aptamer Induced Multicolored AuNCs-WS "Turn on" FRET Nano Platform for Dual-Color Simultaneous Detection of AflatoxinB and Zearalenone.

Mycotoxins posit serious threats to human and animal health, and numerous efforts have been performed to detect the multiple toxins by a single diagnostic approach. To best of our knowledge, for the first time, we synthesized an aptamer induced "turn on" fluorescence resonance energy transfer (FRET) biosensor using dual-color gold nanoclusters (AuNCs), l-proline, and BSA synthesized AuNCs (Lp-AuNCs and BSA-AuNCs), with WS nanosheet for simultaneous recognition of aflatoxinB (AFB) and zearalenone (ZEN) by single excitation. Here, AFB aptamer stabilized blue-emitting AuNCs (AFB-apt-Lp-AuNCs) (at 442 nm) and ZEN aptamer functionalized with red-colored AuNCs (ZEN-apt-BSA-AuNCs) (at 650 nm) were employed as an energy donor and WS nanosheet as a fluorescence quencher.

A "turnon" aptasensor for simultaneous and time-resolved fluorometric determination of zearalenone, trichothecenes A and aflatoxin B using WS as a quencher.

A "turn on" time-resolved fluorometric aptasensor is described for the simultaneous detection of zearalenone (ZEN), trichothecenes A (T-2), and aflatoxin B (AFB). Multicolor-emissive nanoparticles doped with lanthanide ions (Dy, Tb, Eu) were functionalized with respective aptamers and applied as a bioprobe, and tungsten disulfide (WS) nanosheets are used as a quencher of time-resolved fluorescence. The assay exploits the quenching efficiency of WS and the interactions between WS and the respective DNA aptamers.

Simultaneous detection of fumonisin B and ochratoxin A using dual-color, time-resolved luminescent nanoparticles (NaYF: Ce, Tb and NH-Eu/DPA@SiO) as labels.

A rapid and highly sensitive time-resolved fluorescence (TRF)-based aptasensor for simultaneous recognition of mycotoxins ochratoxin A (OTA) and fumonisin B (FB) was developed using multi-color, Ln-doped time-resolved fluorescence nanoparticles (TRF-NPs) (NaYF: Ce, Tb and NH-Eu/DPA@SiO NPs) coupled with complementary strand DNA (cDNA) as luminescence probe and aptamers-conjugated amine-functionalized FeO magnetic nanoparticles (MNPs) act as a capture probe. Under the optimized conditions, the time-resolved fluorescence intensities at 544 and 618 nm corresponded with Tb and Eu, respectively, were used to measure FB (Y = 19,177.1 + (- 12,054.

Sustainable biosynthesis of curdlan from orange waste by using Alcaligenes faecalis: A systematically modeled approach.

This study presents an engineered approach for sustainable biosynthesis of curdlan by Alcaligenes faecalis using orange peels. To confirm the substrate suitability a four step study was organized. Firstly, drying of substrate was carried within temperature range of 60-120 °C, along with the application of moisture diffusion control model.