Enhanced characterization of solid solitary pulmonary nodules with Bayesian analysis-based computer-aided diagnosis.

The aim of this study was to prospectively assess the accuracy gain of Bayesian analysis-based computer-aided diagnosis (CAD) vs human judgment alone in characterizing solitary pulmonary nodules (SPNs) at computed tomography (CT). The study included 100 randomly selected SPNs with a definitive diagnosis. Nodule features at first and follow-up CT scans as well as clinical data were evaluated individually on a 1 to 5 points risk chart by 7 radiologists, firstly blinded then aware of Bayesian Inference Malignancy Calculator (BIMC) model predictions.

Multicenter external validation of two malignancy risk prediction models in patients undergoing 18F-FDG-PET for solitary pulmonary nodule evaluation.

Objectives: To achieve multicentre external validation of the Herder and Bayesian Inference Malignancy Calculator (BIMC) models.

Methods: Two hundred and fifty-nine solitary pulmonary nodules (SPNs) collected from four major hospitals which underwent 18-FDG-PET characterization were included in this multicentre retrospective study. The Herder model was tested on all available lesions (group A).

Multicentre external validation of the BIMC model for solid solitary pulmonary nodule malignancy prediction.

Objectives: To provide multicentre external validation of the Bayesian Inference Malignancy Calculator (BIMC) model by assessing diagnostic accuracy in a cohort of solitary pulmonary nodules (SPNs) collected in a clinic-based setting. To assess model impact on SPN decision analysis and to compare findings with those obtained via the Mayo Clinic model.

Methods: Clinical and imaging data were retrospectively collected from 200 patients from three centres.

Comparing CT colonography and flexible sigmoidoscopy: a randomised trial within a population-based screening programme.

Importance And Aims: The role of CT colonography (CTC) as a colorectal cancer (CRC) screening test is uncertain. The aim of our trial was to compare participation and detection rate (DR) with sigmoidoscopy (flexible sigmoidoscopy (FS)) and CTC in a screening setting.

Design Setting And Participants: We conducted two randomised clinical trials (RCTs).

Distribution of Solid Solitary Pulmonary Nodules within the Lungs on Computed Tomography: A Review of 208 Consecutive Lesions of Biopsy-Proven Nature.

Background: The solitary pulmonary nodule (SPN) is a common radiologic abnormality on chest x-rays or computed tomography (CT) scans of the lungs. The differential diagnosis of SPNs is particularly wide as it includes a multitude of benign as well as malignant entities. Nodule location within the lungs has been proposed as a predictive feature in the literature.

CT Imaging Features in the Characterization of Non-Growing Solid Pulmonary Nodules in Non-Smokers.

Background: A disappearing or persistent solid pulmonary nodule is a neglected clinical entity that still poses serious interpretative issues to date. Traditional knowledge deriving from previous reports suggests particular features, such as smooth edges or regular shape, to be significantly associated with benignity. A large number of benign nodules are reported among smokers in lung cancer screening programmes.

Solid pulmonary nodule risk assessment and decision analysis: comparison of four prediction models in 285 cases.

Objectives: The aim of this study was to compare classification results from four major risk prediction models in a wide population of incidentally detected solitary pulmonary nodules (SPNs) which were selected to crossmatch inclusion criteria for the selected models.

Methods: A total of 285 solitary pulmonary nodules with a definitive diagnosis were evaluated by means of four major risk assessment models developed from non-screening populations, namely the Mayo, Gurney, PKUPH and BIMC models. Accuracy was evaluated by receiver operating characteristic (ROC) area under the curve (AUC) analysis.

Assessing probability of malignancy in solid solitary pulmonary nodules with a new Bayesian calculator: improving diagnostic accuracy by means of expanded and updated features.

Objectives: A crucial point in the work-up of a solitary pulmonary nodule (SPN) is to accurately characterise the lesion on the basis of imaging and clinical data available. We introduce a new Bayesian calculator as a tool to assess and grade SPN risk of malignancy.

Methods: A set of 343 consecutive biopsy or interval proven SPNs was used to develop a calculator to predict SPN probability of malignancy.

Limited value of logistic regression analysis in solid solitary pulmonary nodules characterization: a single-center experience on 288 consecutive cases.

Background And Objectives: Preoperative characterization of the solitary pulmonary nodule is a delicate task faced by surgeons, radiologists, and clinicians. Mathematical models have been developed to overcome subjectivity. The Mayo Clinic model was suggested in the latest ACCP evidence-based clinical practice guidelines for the preoperative risk assessment of solitary pulmonary nodule malignancy.

[Ultrasonography in acute diverticulitis of the colon: semiologic features].

To assess the ultrasonographic (US) patterns of acute colonic diverticulitis, we prospectively examined 21 patients. US was performed in all of them, CT in 13/21, contrast enema in 18/21 and endoscopy in 2/21 patients. US follow-up was carried out in 15/17 patients managed with conservative treatment.

[Do radiologists develop perceptual learning contrast sensitivity?].

A slight difference in brightness between objects close to each other and with no clear-cut outlines separating them can be recognized by the visual function called contrast sensitivity. This function is particularly developed in the radiologist, whose task is to analyze images in many shades of grey and with no clear-cut outlines, due to kinetic and radiogeometrical shading. Assuming that professional habit might develop this function, the authors compared contrast sensitivity in a group of 26 radiologists with contrast sensitivity in a control group (30 non-radiologists).

[The echo-guided percutaneous therapy of dysontogenetic liver cysts].

Congenital hepatic cysts are a frequent disease, symptomatic in 16-18% of the cases. The Authors report their personal experience about 4 cases and they make a review about 56 cases treated with ultrasonically-guided therapy. In 20 cases the therapy was simple aspiration, in 39 was alcohol sclerotherapy and in 1 was external percutaneous drainage.

[Radiological aspects of intestinal lipomas].

The radiological detection of intestinal lipomas is not unusual; however, in-depth studies of their radiological features have never been carried out, so far. Eighteen cases of intestinal lipoma were observed, out of different clinical histories. Through a careful survey of these cases, the authors describe the semiological characteristics of the lipomas, which were studied with radiographic contrast examinations of the small intestine and colon.

[Echographic monitoring of 80 renal transplants. Critical analysis of signs of graft rejection].

In a period of one year and a half, the follow-up of 80 patients after renal transplant has been monitored with echography. Altogether were made 418 echographies, which later were correlated with the clinical conditions of the patients at the moment of each echography. As rejection represents the most important complication, care was particularly given to the possibility of sonographic identification of such pathology.

[Importance of the dimensions and histologic nature of polyps of the colon in a comparison between double contrast enema and colonoscopy].

In 244 patients the results obtained by double contrast barium enema and endoscopy in the detection of small colonic polyps were compared. The results were evaluated by subdividing the polyps according to size. In order to define the endoscopic false positives percentage, controversial cases were re-examined with a second double contrast barium enema.

[Ileal occlusion caused by the rupture and dislocation of a Celestin prosthesis. Radiological aspects. Presentation of 2 cases].

When the Celestin tube is used for treatment of benign oesophageal strictures after several months structural deterioration and fatigue occur. The tube disruption and displacement are serious complications which can be early identified with routine-radiological examinations.