Publications by authors named "Soadad Saleh"
Background: Heart failure (HF) is a complex cardiovascular disease. Effective management typically involves four main medications: angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, beta-blockers, angiotensin receptor-neprilysin inhibitors, and mineralocorticoid receptor antagonists, along with sodium-glucose co-transporter-2 inhibitors (SGLT2i). The primary objective of this article is to assess and identify the utilization of four-pillar regimen for HF managment and explore the characteristics of the patients being on the four-pillar regimen in Jordan.
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- Diabetes management is crucial, and therapeutic drug monitoring, particularly for medications like metformin and glimepiride, can help maintain optimal dosages in patients.
- A study involving 106 type 2 diabetes patients used a validated LC-MS/MS method to measure drug levels and examined the relationship between drug concentration and genetic mutations, particularly focusing on the SULT1A1 genotype.
- Findings indicated a potential correlation between metformin levels and genetic factors, suggesting that tailored (genotype-guided) drug therapy could enhance treatment effectiveness and reduce adverse effects.
Objectives: A drug like Sildenafil is commonly used for the treatment of erectile dysfunction. Eruca sativa is known as a garden plant used in folk medicine to enhance the sexual desire in males. Nevertheless, the interaction of Sildenafil and Eruca sativa was not studied.
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