modulates contact dermatitis in depressed rats through downregulation of proinflammatory cytokines and upregulation of antioxidant status.

Introduction: The link between psychological stress and skin diseases, such as atopic dermatitis is established. Pumpkin was proved to have antioxidant, anti-inflammatory and accelerating wound healing potential.

Aim: To assess the efficacy of pumpkin fruit (.

Alleviates Chronic Unpredictable Mild Stress via Modulation of Apoptosis, Neurogenesis, and Gliosis in Rat Hippocampus.

Pumpkin has received significant attention due to its nutritional compounds that have antioxidant, antifatigue, and anti-inflammatory effects. This study is aimed at assessing the antidepressant-like effect of , sweet pumpkin, in an animal model of chronic unpredictable mild stress (CUMS) and investigating its effect on the histological structure of hippocampus compared to fluoxetine. Forty male albino rats assigned into the negative control, positive control (CUMS), and Flu-treated and pumpkin-treated groups ( = 10) were utilized in this study.

Raisins Preserve Thyroid Gland Function and Structure in an Animal Model of Hypercholesterolemia.

Background: Statins are among the first line of pharmacological treatment of lipid disorders and lowering serum cholesterol, but they have many side effects.

Aim: The study aim was to evaluate the role of raisins in protecting the thyroid function and structure in a rat model of hypercholesterolemia, through biochemical and histopathological investigation.

Materials And Methods: Thirty male rats were randomly divided into three groups ( = 10 each) of albino rats included the control, high cholesterol diet (HCD)-fed for 13 weeks and HCD plus Raisins were included in this study.

Cell talk: a phenomenon observed in the keloid scar by immunohistochemical study.

Keloid is a common complication of the wound healing process. Scarce histologic studies describing changes in keloid growth or progression, regarding detailed descriptions of cellular distribution, relationship, or interaction are available. This study aimed to describe the nature, types, and interactions of immune cells (lymphocytes, macrophages, and mast cells), which predominate in keloid complications and may play a role in fibroblastic activation.