Publications by authors named "SoYoon Park"

Article Synopsis
  • Recent studies show that starting rhythm control early in treating atrial fibrillation (AF) improves heart health outcomes; however, there's not much data on long-term results for patients who don't want radiofrequency catheter ablation (RFCA) after failing antiarrhythmic drugs.
  • A study identified patients with AF who refused RFCA and compared their outcomes with those who underwent RFCA, focusing on all-cause mortality and the occurrence of ischemic stroke.
  • The results indicated that patients who refused RFCA had a much higher rate of ischemic stroke compared to those treated with RFCA, although there was no significant difference in overall death rates between the two groups.
View Article and Find Full Text PDF
Article Synopsis
  • Lumbar facet joint syndrome (FJS) is a frequent cause of chronic low back pain, often treated with radiofrequency techniques when conservative methods fail, but its effectiveness is debated.
  • This study conducted a network meta-analysis (NMA) to evaluate the impact of radiofrequency on FJS by comparing it with other treatments, focusing on pain scores and disability indices.
  • The results indicate that endoscopic neurotomy outperforms radiofrequency treatments in alleviating pain and improving function over time, highlighting the need for more rigorous trials to further validate these findings.
View Article and Find Full Text PDF

With the escalating prevalence of hair loss, the demand for effective hair loss treatment has surged. This study evaluated the effects of hot water extract of (Thunb.) Ser.

View Article and Find Full Text PDF
Article Synopsis
  • * Traditionally, AVNRT is thought to involve two pathways—an upper pathway connecting to the atrium and a lower pathway linking to the ventricle—but there is still debate over the existence of the upper pathway.
  • * While some evidence suggests the atrium isn’t necessary for AVNRT to occur, anatomical studies have not conclusively identified the upper pathway, leading to ongoing discussions about the actual heart circuit involved in AVNRT.
View Article and Find Full Text PDF

Background: Knee osteoarthritis (OA) is a prevalent degenerative disease and causes disability, pain and imposes a substantial burden on patients. Conventional treatments for knee OA show limited effectiveness. Consequently, innovative treatments, such as radiofrequency ablation (RFA) and intra-articular mesenchymal stem cells (IA MSC), have gained attention for addressing these limitations.

View Article and Find Full Text PDF

Obesity is primarily exacerbated by excessive lipid accumulation during adipogenesis, with triacylglycerol (TG) as a major lipid marker. However, as the association between numerous lipid markers and various health conditions has recently been revealed, investigating the lipid metabolism in detail has become necessary. This study investigates the lipid metabolic effects of (Thunb.

View Article and Find Full Text PDF

Obesity requires treatment to mitigate the potential development of further metabolic disorders, including diabetes, hyperlipidemia, tumor growth, and non-alcoholic fatty liver disease. We investigated the anti-obesity effect of a 30% ethanol extract of (Kjellman) Setchell (EEB) on 3T3-L1 preadipocytes and high-fat diet (HFD)-induced obese C57BL/6 mice. Adipogenesis transcription factors including peroxisome proliferator-activated receptor (PPAR)γ, CCAAT/enhancer-binding protein-alpha (C/EBPα), and sterol regulatory element-binding protein-1 (SREBP-1) were ameliorated through the AMP-activated protein kinase (AMPK) pathway by EEB treatment in differentiated 3T3-L1 cells.

View Article and Find Full Text PDF

Background: Despite laparoscopic cholecystectomy (LC) is a commonly performed operation under ambulatory setting, significant postoperative pain is still a major concern. The ultrasound-guided subcostal approach of transversus abdominis plane (sTAP) blocks and wound infiltration (WI) are both widely practiced techniques to reduce postoperative pain in patients undergoing LC. Although these methods have been shown to relieve postoperative pain effectively, the relative analgesic efficacy between ultrasound-guided sTAP blocks and WI is not well known.

View Article and Find Full Text PDF

The rapid and precise detection of pathogenic agents is critical for public health and societal stability. The detection of biological warfare agents (BWAs) is especially vital within military and counter-terrorism contexts, essential in defending against biological threats. Traditional methods, such as polymerase chain reaction (PCR), are limited by their need for specific settings, impacting their adaptability and versatility.

View Article and Find Full Text PDF

With the escalating global awareness of air quality management, the need for continuous and reliable monitoring of toxic gases by using low-power operating systems has become increasingly important. One of which, semiconductor metal oxide gas sensors have received great attention due to their high/fast response and simple working mechanism. More specifically, self-heating metal oxide gas sensors, wherein direct thermal activation in the sensing material, have been sought for their low power-consuming characteristics.

View Article and Find Full Text PDF

Background: Anatomic and electrophysiologic findings suggest that the actual circuit of atrioventricular nodal reentrant tachycardia (AVNRT) involves the perinodal atrium. However, occasional instances in which the atrium is dissociated from the AVNRT have led to the concept of an upper common pathway (UCP).

Objective: We aimed to assess the prevalence of UCP in AVNRT using a late atrial premature depolarization (LAPD) maneuver.

View Article and Find Full Text PDF

Body mass index (BMI), as an important risk factor related to metabolic disease. However, in some studies higher BMI was emphasized as a beneficial factor in the clinical course of patients after acute myocardial infarction (AMI) in a concept known as the "BMI paradox." The purpose of this study was to investigate how clinical outcomes of patients treated for AMI differed according to BMI levels.

View Article and Find Full Text PDF

Introduction: Lumbar radicular pain (LRP) is a common symptom characterised by a sharp, shooting or lancinating sensation localised to one or more dermatomes of the lumbar spine. Despite its high prevalence and significant impact on quality of life, the most effective conservative treatment for patients with LRP remains uncertain. When conventional treatment methods do not provide satisfactory results, the option of using epidural steroids and/or pulsed radiofrequency (PRF) treatment may be considered as a secondary approach for managing the condition.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated the impact of capsulotomy (removal of the capsule) on the infection rates during the replacement of cardiac implantable electronic devices (CIED) in 195 patients over a six-year period.
  • While the results showed some bacterial colonization, the occurrence of device infections requiring surgery was similar in both the intervention (capsule removed) and control (capsule not removed) groups, with rates of 3.1% and 1.0%, respectively.
  • Ultimately, the findings suggest that performing a capsulectomy during CIED generator replacement does not significantly reduce infection risks, and hematoma was identified as a potential risk factor for infection.
View Article and Find Full Text PDF
Article Synopsis
  • - The systematic review aimed to evaluate the effectiveness of pulsed radiofrequency (PRF) treatment on lumbar radicular pain (LRP) compared to local injection (LEI) by analyzing randomized controlled trials up to May 2023.
  • - Out of 10 included studies involving 613 patients, PRF showed no significant differences in pain scores at 1 or 6 months, but did demonstrate a notable pain reduction at 3 months, although overall evidence quality was rated as low to moderate.
  • - The findings suggest that while PRF may reduce pain more effectively than LEI at the 3-month mark for specific patient subgroups, there was no strong evidence to support its overall advantage in treating LRP. *
View Article and Find Full Text PDF
Article Synopsis
  • Ultrasound-indicated cerclage (UIC) is a procedure recommended to prevent spontaneous preterm birth (sPTB) in women with a short cervix and a previous history of preterm birth.
  • A study analyzed factors influencing sPTB after UIC, finding that earlier gestational age and shorter cervical length at the time of UIC were linked to higher risks of sPTB.
  • Additional risk factors included elevated preoperative serum inflammatory markers and obesity, while previous preterm birth did not directly increase sPTB risk but raised chances of needing another cerclage.
View Article and Find Full Text PDF
Article Synopsis
  • The study assessed the effectiveness of using direct oral anticoagulants (DOAC) alone compared to combining them with antiplatelet medication in patients with atrial fibrillation (AF) following a percutaneous coronary intervention (PCI).
  • Both treatment groups experienced a high rate of dose reduction for DOACs (approximately 70% to 79%) and the incidence of major adverse cardiovascular events (MACE) between the two groups was not significantly different, suggesting similar risks.
  • However, there was a trend indicating a higher risk of stroke in the DOAC monotherapy group, but overall outcomes for all-cause death and major bleeding were comparable between the two therapies.
View Article and Find Full Text PDF
Article Synopsis
  • Hydrogen sensors are crucial for quickly detecting the explosive gas in environments where it's used, but previous technologies have struggled to meet all necessary standards.
  • A new electrical hydrogen sensor has been developed, featuring an ultra-fast response time of about 0.6 seconds and reliable performance across varying conditions, including resistance to humidity and other gases.
  • This sensor utilizes advanced design techniques that optimize palladium (Pd) nanowires to ensure accurate detection, and it can wirelessly communicate hydrogen leak information in real-time within just 1 second.
View Article and Find Full Text PDF

Background: Lumbar radicular pain (LRP) is a common but challenging clinical symptom. Pulsed radiofrequency (PRF), a neuromodulation technique that uses short pulses of radiofrequency current, is effective in treating various pain disorders. However, few studies have been conducted on the effects of PRF and its modifying parameters.

View Article and Find Full Text PDF

Accurate assessment of the response to the antiarrhythmic drug (AAD) in atrial fibrillation (AF) is crucial to achieve adequate rhythm control. We evaluated the effectiveness of extended cardiac monitoring using an adhesive ECG patch in the detection of drug-refractory paroxysmal AF. Patients diagnosed with paroxysmal AF and receiving AAD therapy were enrolled.

View Article and Find Full Text PDF

Antioxidant and anti-inflammatory mechanisms counteract the pathogenesis of chronic diseases, such as diabetes, aging, and cancer. Therefore, enhancing antioxidant and anti-inflammatory functions may help manage these pathological conditions. This study aimed to assess the antioxidant and anti-inflammatory potentials of lipophilic fraction of seeds (LLPS) using network pharmacology, molecular docking, and in vitro experiments.

View Article and Find Full Text PDF
Article Synopsis
  • SGLT2 inhibitors (SGLT2is) have been linked to better cardiovascular health and lower rates of atrial fibrillation (AF) in type 2 diabetes patients.
  • A study analyzed data from 11,012 patients with both AF and diabetes to compare outcomes between those using SGLT2is and those who weren't, resulting in significant findings favoring SGLT2i users.
  • The results revealed a lower incidence of death or heart failure hospitalizations for SGLT2i users compared to non-users, along with reduced adverse renal events.
View Article and Find Full Text PDF

Objectives: In this study, we aimed to provide a more valuable diagnostic parameter and more equivocal assessment of the diagnostic potential of patellofemoral pain syndrome (PFPS) by comparing the quadriceps tendon cross-sectional area (QTCSA) with the quadriceps tendon thickness (QTT), a traditional measure of quadriceps tendon hypertrophy.

Patients And Methods: Between March 2014 and August 2020, a total of 30 patients with PFPS (16 males, 14 females; mean age, 30.4±11.

View Article and Find Full Text PDF