Peiminine Exerts Its Anti-Acne Effects by Regulating the NF-κB Pathway.

Peiminine is the main natural alkaloid compound extracted from the Chinese herb Fritillaria. Although peiminine is known for its antioxidant and anti-inflammatory effects in conditions such as mastitis and arthritis, its impact on inflammation induced by () has not been explored. The aim of this study was to investigate the effect of peiminine on -induced inflammatory responses in the skin and to identify the underlying mechanism involved.