Publications by authors named "So Hyeon Gwon"
Article Synopsis
- This study investigates the efficacy, safety, and pharmacokinetics of an 80 mg daily dose of osimertinib in patients with leptomeningeal metastases (LMs) who have previously been treated with other EGFR tyrosine kinase inhibitors (TKIs).
- A total of 73 patients were treated, and findings include a median overall survival of 15.6 months and a 51.6% objective response rate, indicating substantial effectiveness in controlling the disease.
- The results support the use of osimertinib as a promising treatment option for patients with EGFR-mutated non-small cell lung cancer who develop LMs, highlighting its significant intracranial activity and manageable safety profile.
This study aimed to evaluate the safety and efficacy of intra-arterial (IA) administration of low- dose tirofiban during endovascular therapy in patients with large ischemic core volumes on initial brain CT. Patients were divided into two groups based on the use of IA tirofiban. We identified 87 patients (16 and 71 patients in the tirofiban and no-tirofiban groups, respectively) with acute ischemic stroke due to intracranial artery occlusion who underwent endovascular therapy with a low Alberta Stroke Program Early CT scores (2-5).
View Article and Find Full Text PDFNumerous environmental factors that influence myopia have been studied, but only few factors have been definitively identified. We examined factors influencing myopia using data from 2014 to 2020 physical examinations received from the Korean Military Manpower Administration. We used the Cochran-Armitage trend test to investigate the annual prevalence of myopia and high myopia.
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