LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in A3(2).

Actinobacteria utilize various polysaccharides in the soil as carbon source by degrading them via extracellular hydrolytic enzymes. Agarose, a marine algal polysaccharide composed of D-galactose and 3,6-anhydro-L-galactose (AHG), is one of the carbon sources used by A3(2). However, little is known about agar hydrolysis in A3(2), except that the regulation of agar hydrolysis metabolism is strongly inhibited by glucose as in the catabolic pathways of other polysaccharides.