Publications by authors named "Snigdhendu Mandal"

Platypnoea orthodeoxia syndrome is a rare condition, which can be present in patients with patent foramen ovale (PFO). In this case, a 72-year-old lady presented to the emergency department with a cryptogenic stroke associated with right thalamic infarct. While in hospital, it was noticed that the patient had desaturations in the upright position, and these improved in the recumbent position, consistent with platypnoea orthodeoxia syndrome.

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Article Synopsis
  • Amiodarone can cause thyroid issues, particularly a condition called amiodarone-induced thyrotoxicosis (AIT), which comes in two types: AIT 1 is linked to pre-existing autoimmune issues, while AIT 2 occurs in otherwise healthy thyroids and involves tissue damage.
  • AIT 1 is typically treated with thionamides, while AIT 2 is managed with steroids; however, some cases can resist standard treatments, as seen in this report.
  • The patient in the case study was resistant to high doses of carbimazole and steroids, but treatment with cholestyramine led to significant improvements, ultimately stabilizing the patient's thyroid function.
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Background and aim Gram-negative rods (GNR) are the most common pathogens associated with urinary tract infections (UTI). The resistance of these gram-negative rods to various antibiotics is increasing with time. The study aimed to determine the pattern of resistance to antibiotics in GNR causing urinary tract infection in adults.

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