Publications by authors named "Snezhko E"

Article Synopsis
  • Drug resistance in cancer chemotherapy is a major issue, with cancer cells often shifting to fatty acid metabolism to evade treatment.
  • The researchers created a drug called folate-polySia (FpSA) that induces microcalcification in cervical cancer cells resistant to cisplatin, leading to decreased fatty acid uptake and increased glycolysis.
  • The combination of cisplatin and FpSA not only inhibited tumor growth but also improved survival rates in mice, suggesting a new strategy to tackle chemotherapy-resistant tumors by reprogramming cancer cell metabolism.
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The TB Portals program is an international consortium of physicians, radiologists, and microbiologists from countries with a heavy burden of drug-resistant tuberculosis working with data scientists and information technology professionals. Together, we have built the TB Portals, a repository of socioeconomic/geographic, clinical, laboratory, radiological, and genomic data from patient cases of drug-resistant tuberculosis backed by shareable, physical samples. Currently, there are 1,299 total cases from five country sites (Azerbaijan, Belarus, Moldova, Georgia, and Romania), 976 (75.

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Recent years have seen tremendous progress towards therapy of many previously incurable neuromuscular diseases. This new context has acted as a driving force for the development of novel non-invasive outcome measures. These can be organized in three main categories: functional tools, fluid biomarkers and imagery.

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The concepts of the modern computer-aided diagnosis (CAD), the methods of pulmonary nodules detection and facts derived from the available literature on the pulmonary nodule differential CAD topic are compiled in one source and described in some details. Several issues of the lung cancer epidemiology and an early diagnosis are discussed. The analysis of the performed research shows an evidence that various CAD systems can be successfully applied for chest radiographs, computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET).

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