Background: Pain is the leading cause of disability and reduced quality of life worldwide. Despite the increasing burden for patients and healthcare systems, pain research remains underfunded and under focused. Having stakeholders identify and prioritize areas that need urgent attention in the field will help focus funding topics, reduce 'research waste', improve the effectiveness of pain research and therapy and promote the uptake of research evidence.
View Article and Find Full Text PDFIn a functional magnetic resonance imaging study, we examined speech error monitoring in a cortico-cerebellar network for two contrasts: (a) correct trials with high versus low articulatory error probability and (b) overtly committed errors versus correct trials. Engagement of the cognitive cerebellar region Crus I in both contrasts suggests that this region is involved in overarching performance monitoring. The activation of cerebellar motor regions (superior medial cerebellum, lobules VI and VIII) indicates the additional presence of a sensorimotor driven implementation of control.
View Article and Find Full Text PDFBackground: In the medical literature several classifications of the pelvis according to its shape can be found. The most common classification distinguishes four general pelvis types: gynecoid, android, anthropoid and platypelloid. Natural childbirth may be significantly prolonged, difficult or even impossible if the pelvis shape is not in proportion to the size of the fetus.
View Article and Find Full Text PDFIntroduction: Osteoporosis, a disease characterized by the progressive loss of bone tissue, is one of the most common complications of aging.
Epidemiology: According to some calculations, there were 25% of women and 4% of men older than 50 years with osteoporosis in the world in 2010. It is assumed that the number of patients with osteoporosis will increase by 30% in every 10 years in the 21st century.
Introduction: Stroke is the second leading cause of death in the world and the leading cause of serious, long-term disability in adults; about half of those who survive become dependent on others in performing personal activities of daily living. Ischemia disturbs calcium cellular homeostasis, whereas calcium channel blockers re-establish it. This study was aimed at assessing benefits of calcium channel blockers on the outcome of rehabilitation of the patients afflicted by ischemic stroke.
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