Comparison of Imaging Modalities in Differentiating Cerebral Neoplastic Lesions and Post-radiation Necrosis.

Neuroimaging of cerebral neoplastic lesions and post-radiation necrosis (PRN) presents significant challenges due to their overlapping features, making differentiation difficult. The use of various imaging modalities in association with radiation therapy introduces potential risks and prognostic variations that can affect lesion physiology. Patients who undergo radiation treatment inevitably experience changes influenced by factors such as radiation dose, brain volume, and tumor fraction size.