Publications by authors named "Smit Thakkar"
Background: A frequent sleep condition linked to considerable morbidity and death is obstructive sleep apnea (OSA). Continuous positive airway pressure (CPAP) therapy is not the only noninvasive treatment option for OSA. Another option is oral appliance therapy (OAT).
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- - This study evaluated the diagnostic value of four urinary biomarkers in male patients with type 2 diabetes and nephropathy over a 9-month period, comparing them to diabetic patients without nephropathy as a control group.
- - Key findings showed that the urinary biomarker AGT (angiotensinogen) had the highest diagnostic performance, with an area under the curve (AUC) of 0.91, indicating strong sensitivity and specificity for identifying diabetic nephropathy.
- - The research concludes that urinary AGT is a more effective marker than others for detecting diabetic nephropathy before albuminuria occurs and recommends further studies to support these findings.
Introduction: In today's healthcare environment, peripheral venous cannulations are frequently performed procedures. Bloodstream infections could occur as a result of the intrusive operation. Peripheral venous cannulas should be inserted and managed according to specific rules.
View Article and Find Full Text PDFObjective: The purpose of this systematic review and meta-analysis was to determine whether there is a connection between polycystic ovarian syndrome (PCOS)-affected women's levels of the anti-Mullerian hormone (AMH) and certain cardiometabolic indicators.
Materials And Methods: To find pertinent recent research published between 2017 and 2023, a thorough search was done in PubMed. Studies were included if they looked into the relationship between PCOS-related women's AMH levels and cardiometabolic markers.
Introduction: The impact that vitamin D (vit D) has on a variety of medical conditions like diabetes, cardiovascular, oncological, and central nervous system disorders has been a topic of interest for many years now. It is well-known that vit D deficiency is substantially more common in epileptics than in healthy subjects. The current research was piloted to analyse the vit D levels of the blood in newborns with seizures, as well as mothers' vit D status included subjects.
View Article and Find Full Text PDFIntroduction: In the first trimester, almost one in five identified pregnancies end in spontaneous miscarriage, and another 22% result in induced abortion. After a spontaneous and/or induced abortion, there may be retained products of conception (POC). Because of its relatively poor efficacy and the unpredictability of the time interval until spontaneous evacuation, expectant treatment is not often chosen by healthcare professionals.
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- Osteoarthrosis (OA) is a slowly progressing condition that leads to significant discomfort, and platelet-rich plasma (PRP) therapy is being explored as an effective treatment for knee OA.
- A year-long clinical study involved 80 patients over 50 years old with symptomatic knee OA, who received PRP injections and were assessed using VAS and WOMAC questionnaires before and after treatment.
- Results showed significant improvements in patients' pain and function after 12 weeks, indicating that PRP therapy is a cost-effective and simple option for managing knee pain related to OA.
Introduction: Although sevoflurane and desflurane have nearly identical blood-gas solubilities, current research suggests that airway reflexes recover more quickly with desflurane than sevoflurane; however, cognitive function recovery varies substantially. The current study was piloted to appraise the lengths of time needed to recover from anesthesia following desflurane and sevoflurane anesthesia.
Materials And Methods: A prospective clinical trial was piloted among 70 adult non-obese subjects who underwent elective surgery and were classified I-II by the " (ASA)".
Objectives: This study aimed to investigate whether the format and type of conclusion in Cochrane plain language summaries (PLSs) influence readers' perception of treatment benefit and decision-making.
Design: An online parallel group, three-arm randomised controlled trial was conducted.
Setting: The study was conducted online.