Publications by authors named "Smiddy W"
Article Synopsis
- Central Serous Chorioretinopathy (CSC) is characterized by retinal detachments due to fluid leakage, often linked to stress, psychiatric issues, or corticosteroid use, prompting a study to investigate BALAD as a potential biomarker for CSC severity.
- The research involved a global case-control study of patients with CSC, assessing clinical characteristics, risk factors, and OCT findings in those with and without Bacillary Layer Detachment (BALAD) to better understand its implications in diagnosis and treatment.
- Results showed 37 patients with CSC and BALAD, revealing distinct clinical features on examination and OCT, compared to a control group without BALAD, suggesting significant differences in the manifestation of CSC.
Article Synopsis
- The study looked at 20 eyes from 14 patients who had surgery due to problems caused by two eye diseases: sickle cell retinopathy and diabetic retinopathy.
- Most of the surgeries were done because of serious issues like retinal detachments or bleeding inside the eye.
- The results showed that the surgery didn't really improve vision for most patients, and only some had successful fixes to their retinal problems.
Article Synopsis
- The study assessed the cost effectiveness of treating geographic atrophy (GA) using two different medications: intravitreal avacincaptad pegol (ACP) and pegcetacoplan (PEG).
- Cost analyses were conducted using 2022 Medicare reimbursement data, focusing on both hospital and non-hospital settings in Miami, with treatment outcomes drawn from previous clinical trials.
- Results showed that while ACP treatment had varying costs based on treatment frequency, it was generally less cost effective for extrafoveal lesions compared to PEG, with EOM (every other month) treatment being more cost effective than EM (every month) for ACP.
Faricimab in Previously Treated Eyes With Neovascular Age-Related Macular Degeneration: An Assessment of Durability and Treatment Outcomes.
Ophthalmic Surg Lasers Imaging Retina
September 2024
Background And Objective: This study evaluated the efficacy and durability of faricimab in patients with neovascular age-related macular degeneration (nAMD) who were previously treated with anti-vascular endothelial growth factor (anti-VEGF) agents.
Patients And Methods: This retrospective case series was conducted at a single tertiary center in the United States. It focused on nAMD patients who transitioned to faricimab after initial anti-VEGF therapy, with a follow-up period of at least 9 months.
Article Synopsis
- This study looked at how patients with a serious eye problem caused by sickle cell disease did after they had surgery.
- They found that most patients who had surgery for retinal detachment got better, especially if they had a specific type of surgery called SB/PPV.
- Overall, the results showed that the type of sickle cell disease didn’t really change how well the patients did after the surgery.
Purpose: To present a surgical modification to a previously published technique that allows repositioning and scleral fixation of one-piece acrylic intraocular lenses with tapered haptics.
Methods: A retrospective review of three consecutive cases.
Results: Our technique modification enables repositioning using scleral suture fixation of one-piece intraocular lenses with tapered haptics by looping the haptic at its proximal, notched junction to the optic with the polypropylene suture.
Purpose: To investigate best corrected visual acuity (BCVA), subretinal fluid (SRF) absorption time or ellipsoid zone (EZ) restoration time and various variables in patients with persistent SRF after successful primary repair of rhegmatogenous retinal detachment (RRD).
Methods: This retrospective multicenter study allowed independent analysis of the healing pattern by two observers based on composite of serial cross-sectional macular optical coherence tomography (OCT) scans. Univariate and multivariate analyses were implemented.
Purpose: To evaluate the cost-effectiveness of the treatment of geography atrophy (GA) with intravitreal pegcetacoplan and to identify utility-measurement surrogates.
Design: Cost analysis based on data from a published study.
Subjects: None; based on data from published sham control compared with 2 treatment groups in the index study.
Purpose: To report the surgical approaches and outcomes in patients undergoing surgery for retinal detachment associated with retinal dialysis.
Design: Retrospective, consecutive case series.
Subjects: All patients who underwent surgery for retinal detachment secondary to retinal dialysis between January 1, 2012, and January 1, 2022.
Purpose: We evaluated the clinical outcomes of intraocular inflammation (IOI) of eyes with neovascular age-related macular degeneration (AMD) injected with brolucizumab in our tertiary referral center.
Methods: A retrospective case series for which clinical records of all eyes that received intravitreal brolucizumab at Bascom Palmer Eye Institute between December 1, 2019, and April 1, 2021, were reviewed.
Results: There were 345 eyes of 278 patients who received 801 brolucizumab injections.
Aim: To analyze and calculate the relative cost of various childhood glaucoma surgical interventions per mm Hg intraocular pressure (IOP) reduction ($/mm Hg).
Methods: Representative index studies were reviewed to quantitate the reduction of mean IOP and glaucoma medications for each surgical intervention in childhood glaucoma. A US perspective was adopted, using Medicare allowable costs to calculate cost/mm Hg IOP reduction ($/mm Hg) at 1y postoperatively.
To describe a patient who presented with visual loss and an apparent hypopyon but none of the other symptoms or signs most common with infectious endophthalmitis. A case and its findings were analyzed. A 73-year-old woman was treated with intravitreal triamcinolone acetonide (IVTA) for cystoid macular edema.
View Article and Find Full Text PDFPurpose: To evaluate the outcomes and complications in patients with retained lens fragments (RLF) after cataract surgery, comparing those who received pars plana vitrectomy (PPV) on the same day, within 1 week, or later than 1 week after cataract surgery.
Patients And Methods: Retrospective case series of all patients who underwent PPV for RLF at Bascom Palmer Eye Institute between January 1, 2012 and September 30, 2020. Individuals with less than 3 months of follow-up, chronic uveitis, congenital cataract, previtrectomy retinal detachment (RD), and severe trauma were excluded.
Purpose: The purpose of the study was to report the clinical features and best-corrected visual acuity outcomes in patients with acute- and delayed-onset endophthalmitis after open globe injuries.
Methods: The study included a retrospective, comparative, consecutive case series of patients with endophthalmitis after open globe injury between January 2016 and October 2020 at the Bascom Palmer Eye Institute.
Results: Acute-onset endophthalmitis accounted for 16 of 20 cases (80%), and all cases were diagnosed at the initial examination.
Purpose: To investigate closure rates and functional outcomes of surgery for refractory and recurrent macular holes (MHs) in a real-world setting.
Methods: Retrospective review of secondary MH surgeries.
Results: A total of 72 eyes from 72 patients were included.
Purpose: Identify the long-term rate of fellow eye full-thickness macular hole (FTMH) development.
Patients And Methods: In this single site, single provider retrospective consecutive case series, idiopathic FTMH patients who underwent surgery from 2003 to 2014 who also had at least 5 years of follow-up information within our electronic medical record (EMR) which was started in 2014 were identified. Cases with secondary causes (ie, trauma), high myopia, bilateral FTMH on presentation, previous retinal surgery, retinal breaks, or intraocular inflammation were excluded.
Objective: The purpose of the current study is to report outcomes of suprachoroidal hemorrhage (SCH) after anterior segment surgery at a single institution, and to identify clinical features associated with visual prognosis.
Methods And Analysis: Retrospective consecutive case series of patients with SCH occurring after anterior segment surgery.
Results: The study includes 112 eyes of 112 patients between 2014 and 2020.
Purpose: To calculate the costs of treatment for diabetic macular edema with bevacizumab-first (step therapy) compared with aflibercept monotherapy.
Design: Cost analysis of the treatment arms based on a published study.
Subjects: None.
Giant Retinal Tears: Long-Term Outcomes of Fellow Eyes.
Ophthalmic Surg Lasers Imaging Retina
November 2022
Background And Objective: Determine clinical characteristics and long-term outcomes of fellow eyes for patients with prior repair of rhegmatogenous retinal detachments due to a giant retinal tear (GRT).
Study Design: Retrospective case series of patients who underwent vitreoretinal surgery between January 2005 and August 2017 for GRT at the Bascom Palmer Eye Institute with a minimum of one year of follow-up information. Patients with a traumatic or post-vitrectomy GRT were excluded.