Break through the mold: Hyper-IgE syndrome as a vehicle for invasive aspergillosis.

Hyperimmunoglobulin E syndrome (HIGES) is a rare immunodeficiency characterized by high levels of immunoglobulin E (IgE) in the setting of various clinical features such as cutaneous candidiasis, asthma, recurrent rashes, and fungal infections. This case describes a 70-year-old male with cachexia and dyspnea found to have a cavitary lesion and aspergilloma, with remarkably high IgE and positive 1,3-β-D-glucan and Aspergillus testing. Herein, we describe the aforementioned case, review the available literature, and hypothesize the connection between invasive fungal infections and HIGES.

Plant-Based Dairy Alternatives Contribute to a Healthy and Sustainable Diet.

Plant-based foods are increasing in popularity as more and more people are concerned about personal and planetary health. The consumption of plant-based dairy alternatives (PBDAs) has assumed a more significant dietary role in populations shifting to more sustainable eating habits. Plant-based drinks (PBDs) made from soya and other legumes have ample protein levels.

Empagliflozin improves insulin sensitivity in patients with recent acute coronary syndrome and newly detected dysglycaemia : Experiences from the randomized, controlled SOCOGAMI trial.

Background: Empagliflozin reduces the risk of cardiovascular disease (CVD) in patients with type 2 diabetes (T2DM) and high cardiovascular risk via mechanisms which have not been fully explained. The mechanisms of such benefit have not been fully understood, and whether empagliflozin can be safely administered as first-line treatment in patients with CVD at the initial stages of glycaemic perturbations remains to be established. We investigated the effects of empagliflozin on insulin resistance, insulin sensitivity and β-cell function indexes in patients with a recent acute coronary event and newly detected dysglycaemia, i.

Metabolic Modeling of Larvae Resource Allocation for High-Value Fatty Acid Production.

All plant and animal kingdom organisms use highly connected biochemical networks to facilitate sustaining, proliferation, and growth functions. While the biochemical network details are well known, the understanding of the intense regulation principles is still limited. We chose to investigate the fly at the larval stage because this stage is a crucial period for the successful accumulation and allocation of resources for the subsequent organism's developmental stages.

Meat substitutes: Resource demands and environmental footprints.

The modern food system is characterized with high environmental impact, which is in many cases associated with increased rates of animal production and overconsumption. The adoption of alternatives to meat proteins (insects, plants, mycoprotein, microalgae, cultured meat, etc.) might potentially influence the environmental impact and human health in a positive or negative way but could also trigger indirect impacts with higher consumption rates.

Transformation of Seafood Side-Streams and Residuals into Valuable Products.

Seafood processing creates enormous amounts of side-streams. This review deals with the use of seafood side-streams for transformation into valuable products and identifies suitable approaches for making use of it for different purposes. Starting at the stage of catching fish to its selling point, many of the fish parts, such as head, skin, tail, fillet cut-offs, and the viscera, are wasted.

Modeling obesity in complex food systems: Systematic review.

Obesity-related data derived from multiple complex systems spanning media, social, economic, food activity, health records, and infrastructure (sensors, smartphones, etc.) can assist us in understanding the relationship between obesity drivers for more efficient prevention and treatment. Reviewed literature shows a growing adaptation of the machine-learning model in recent years dealing with mechanisms and interventions in social influence, nutritional diet, eating behavior, physical activity, built environment, obesity prevalence prediction, distribution, and healthcare cost-related outcomes of obesity.

Edible Insect Farming in the Context of the EU Regulations and Marketing-An Overview.

Insects are increasingly being considered as an attractive source of protein that can cater to the growing demand for food around the world and promote the development of sustainable food systems. Commercial insect farms have been established in various countries, mainly in Asia, but in Europe, edible insects have not yet emerged as a viable alternative to traditional plant- and animal-based sources of protein. In this paper, we present an interdisciplinary overview of the technological aspects of edible insect farming in the context of the EU regulations and marketing.

An automated, modular system for organic waste utilization using heterotrophic alga Galdieria sulphuraria: Design considerations and sustainability.

Large amounts of food are wasted and valuable contents are not utilized completely. Methods to process such wastes into biomass of defined composition automatically and in decentralized locations are lacking. Thus, this study presents a modular design for residue utilization and continuous production of the heterotrophic alga Galdieria sulphuraria.

Black soldier fly larvae (BSFL) and their affinity for organic waste processing.

There are two major problems that we are facing currently. Firstly, a growing human population continues to contribute to the increased food demand. Secondly, the volume of organic waste produced will threaten human health and the quality of the environment.

The impact of Corona pandemic on consumer's food consumption: Vulnerability of households with children and income losses and change in sustainable consumption behavior.

Unlabelled: The ongoing corona crisis affected many people worldwide by restrictions in their everyday lives. The question arises to what extent the pandemic has accelerated diet trends or general differences in food consumption between different population groups. For this purpose, an online-survey was carried out in order to determine the effects of the corona lockdown on food consumption, shopping behaviour and eating habits in Germany.

Comparative life cycle assessment of a mesh ultra-thin layer photobioreactor and a tubular glass photobioreactor for the production of bioactive algae extracts.

This study aimed at the comparison of two different photobioreactors with focus on technology and sustainability. The mesh ultra-thin layer photobioreactor (MUTL-PBR) exhibited around 3-fold biomass based space-time-yield and an around 10-fold specific antioxidant capacity than the traditional reference photobioreactor. Life cycle assessment (LCA) was done under autotrophic conditions in both pilot scale reactors with focus on biomass production and on antioxidant capacity of the biomass, respectively.

Cultivation of the heterotrophic microalga Galdieria sulphuraria on food waste: A Life Cycle Assessment.

The aim of this study was to perform a Life Cycle Assessment of a production process of 1 kg dry algal biomass powder (Galdieria sulphuraria) with 27 % (w/w) protein content for human consumption for optimizing the production regarding global warming potential and resource efficiency in combination with food waste utilization. It was investigated, underpinned by a comparison of the use of conventional glucose, whether and to what extent the environmental impact/global warming potential can be reduced by changing to food waste hydrolysate and how this can lead to a more sustainable use of resources and a sustainable development. Overall, the results showed that hydrolysis, along with freeze-drying, caused most of the overall impact.

Life cycle assessment of hetero- and phototrophic as well as combined cultivations of Galdieria sulphuraria.

Microalgae cultivation for food purposes could have high environmental impacts. The study performed life cycle assessment (LCA) of hypothetical model combining phototrophic and heterotrophic cultivations, exchanging produced gases (carbon dioxide from heterotrophic and oxygen from autotrophic) as a potential strategy to reduce the environmental impact of microalgae cultivation. The LCA indicated that the production of Galdieria sulphuraria in a combined cultivation system has environmental benefits compared with the separate phototrophic cultivation and an almost twice lower carbon footprint than phototrophic cultivation.

Discrete Choice Analysis of Consumer Preferences for Meathybrids-Findings from Germany and Belgium.

High levels of meat consumption are increasingly being criticised for ethical, environmental and social reasons. Plant-based meat substitutes have been identified as healthy sources of protein that, in comparison to meat, offer a number of social, environmental and health benefits and may play a role in reducing meat consumption. However, there has been a lack of research on the role they can play in the policy agenda and how specific meat substitute attributes can influence consumers to partially replace meat in their diets.

Can we associate environmental footprints with production and consumption using Monte Carlo simulation? Case study with pork meat.

Background: Growing population demands more animal protein products. Pork remains one of the traditional and relatively sustainable types of meats for human consumption. In this paper, life-cycle assessment was performed using data from 12 pig farms.

High-pressure processing of usually discarded dry aged beef trimmings for subsequent processing.

In this study, we investigated if the usually discarded trimmings from dry aged beef can be incorporated into raw fermented sausages as a substitute for fresh beef without altering any major characteristics. Dry aged trimmings were subjected to high-pressure processing (600 MPa, 3 min hold) to reduce the bacterial load, achieving a 3-log reduction. HPP-treated dry aged beef trimmings were then incorporated into raw fermented sausages (60% pork and 40% beef).

Bio-refinery of Chlorella sorokiniana with pulsed electric field pre-treatment.

The aim of this work was to investigate the potential of PEF technology for green extraction of microalgal pigments and lipids from fresh Chlorella sorokiniana suspensions. Efficiencies of PEF treatment and different solvent systems application to C.sorokiniana were compared to efficiencies of untreated biomass extraction.

Estimation of the economy of heterotrophic microalgae- and insect-based food waste utilization processes.

An estimation of the economy of Hermetia illucens and Chlorella pyrenoidosa cultivations as food waste treatment with benefits was carried out. For both organisms, a process scale was assumed to treat 56.3 t of wet food waste per day, which is equivalent to the amount of food waste appearing in a catchment area of 141,000 inhabitants.

Nutritional Sustainability Inside-Marketing Sustainability as an Inherent Ingredient.

Current discussions about the concept of nutritional sustainability show a high complexity of this topic leading to many different definitions. Regarding communication issues of nutritional sustainability between actors of food chains this complexity should be reduced. One opportunity to tackle these challenges of reducing complexity might be the concept of ingredient branding.

A Path From Sustainable Nutrition to Nutritional Sustainability of Complex Food Systems.

Integration of nutritional and sustainable aspects is a complex task tackled by a few scientific concepts. They include multiple dimensions and functions of food systems trying to provide solutions for harmonic co-evolution of humanity and planet Earth. "Nutritional Sustainability" is differentiated from other concepts which combine nutrition and sustainability as it not only sets environmental sustaining capacity as a baseline level for balanced nutrition, but also aims for the search of food system driving nodes.