Beyond the blade: Unveiling the nexus of spirituality and human dissection among medical and allied health students in Nigeria.

This study investigated how human dissection affects students' spiritual beliefs, and how their existing spiritual beliefs influence their perceptions of human dissection. This cross-sectional study assessed 760 medical students with human dissection experience using an online questionnaire developed from interviews and the Spirituality Orientation Inventory, including questions on dissection experience, spirituality, spiritual perceptions about dissection, and the impact of dissection on spirituality. Descriptive analysis and Chi-squared tests were used to determine proportions and relationships between variables, with statistical significance at p < 0.

The methanolic extract of downregulates the relative expression of 1 gene in the hypothalamus of Wistar rats: A preliminary report.

Objective: 1 gene expression in the rat hypothalamus was investigated following administration of methanolic extract of (MEHS) to provide mechanistic evidence for the reproductive effect of the MEHS as a potential regulator of 1 gene (which directly controls the hypogonadal axis).

Materials And Methods: This experiment was done using fifteen (15) male rats with average weight of 148 g, randomly grouped into three (3) groups (A-C). Group A was the control group and received no treatment.

Institutionalizing Open Science in Africa: Limitations and Prospects.

The advancement of scientific research and raising the next-generation scientists in Africa depend largely on science access. The COVID-19 pandemic has caused discussions around open science (OS) to reemerge globally, especially in resource-poor settings like Africa, where the practice of OS is low. The authors highlighted the elements, benefits, and existing initiatives of OS in Africa.

Differential Expression of CD31 and Von Willebrand Factor on Endothelial Cells in Different Regions of the Human Brain: Potential Implications for Cerebral Malaria Pathogenesis.

Cerebral microvascular endothelial cells (CMVECs) line the vascular system of the brain and are the chief cells in the formation and function of the blood brain barrier (BBB). These cells are heterogeneous along the cerebral vasculature and any dysfunctional state in these cells can result in a local loss of function of the BBB in any region of the brain. There is currently no report on the distribution and variation of the CMVECs in different brain regions in humans.

Human Microglia Respond to Malaria-Induced Extracellular Vesicles.

Microglia are the chief immune cells of the brain and have been reported to be activated in severe malaria. Their activation may drive towards neuroinflammation in cerebral malaria. Malaria-infected red blood cell derived-extracellular vesicles (MiREVs) are produced during the blood stage of malaria infection.