CO induced phase transition on a self-standing droplet studied by X-ray scattering and magnetic resonance.

Hypothesis: Acoustic levitation is a suitable approach for studying processes occurring at the gas-liquid interfaces, as it allows its investigation in a contact-free manner while providing control over the gas phase. Here, we hypothesize that phase transitions induced by a CO rich atmosphere can be examined, at different length scales, in a contact-free manner.

Experimental: A system consisting of 12-hydroxysteric acid (HSA) soaps mixed with different ratios of monoethanolamine (MEA) and choline hydroxide, was prepared.

Contact-free measurement of surface tension on single droplet using machine learning and acoustic levitation.

Hypothesis: Acoustic levitation provides the possibility to deform levitated droplets in a controllable, and quantifiable manner, thus offering a means to measure the surface tension of a liquid droplet based on its deviation from sphericity. However, for new generation of multi-source and highly stable acoustic levitators, no model relates the acoustic pressure field to the deformation and surface tension. Utilizing a machine learning algorithm is expected to identify correlations between the experimental data without any set preconditions.

Assessment of DNA Topoisomerase I Unwinding Activity, Radical Scavenging Capacity, and Inhibition of Breast Cancer Cell Viability of -alkyl-acridones and ,-dialkyl-9,9'-biacridylidenes.

The anticancer activity of acridone derivatives has attracted increasing interest, therefore, a variety of substituted analogs belonging to this family have been developed and evaluated for their anti-cancer properties. A series of -alkyl-acridones - and ,'-dialkyl-9,9'-biacridylidenes - with variable alkyl chains were examined for their topoisomerase I activity at neutral and acidic conditions as well as for their binding capacity to calf thymus and possible radical trapping antioxidant activity. It was found that at a neutral pH, topoisomerase I activity of both classes of compounds was similar, while under acidic conditions, enhanced intercalation was observed.