Aims: The aim of the present review was to highlight natural product investigations in silico and in vitro to find plants and chemicals that inhibit or stimulate angiotensin-converting enzyme 2 (ACE-2).
Background: The global reduction of incidents and fatalities attributable to infections with SARS-CoV-2 is one of the most public health problems. In the absence of specific therapy for coronavirus disease 2019 (COVID-19), phytocompounds generated from plant extracts may be a promising strategy worth further investigation, motivating researchers to evaluate the safety and anti-SARS-CoV-2 effectiveness of these ingredients.
Fitoterapia
September 2024
Background: Buxus plants have been used in traditional medicine for a very long time. The Buxus genus has been used to cure a variety of illnesses.
Objective: This review aimed to provide a literature review on the genus Buxus including its biological and phytochemical properties.
Cardiovasc Hematol Agents Med Chem
January 2024
The genus Anabasis has long been used in phytomedicine. The studied parts of Anabasis species are used as antirheumatic, diuretic, antidotes against poison, anti-erosion, anti-ulcer, and antidiabetic agents, as well as against headache and skin diseases. The objective of the present review was to summarize the phytochemical and pharmacological aspects related to the genus Anabasis.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
September 2024
Aims: This review aimed to review the biological, pharmacological, and phytochemical aspects of the genus .
Background: Plants of the genus have been used for a long time in traditional medicine, and they are distributed in the western Mediterranean region to the Middle East, Iran, Mongolia, Burma, and southwest China. The studied parts of species include aerial parts, leaves, branches, seeds, roots, rhizosphere, soil, and whole plants, used to treat several diseases, including sexual disorders, hepatobiliary disorders, eye disorders, skin diseases and hemorrhoids, diarrhea, and effective in the treatment of various ailments such as snake bite, stomach ache, diabetes, wounds, earache and sciatica pain, windbreak dune fixation, feeding of livestock and firewood.
Endocr Metab Immune Disord Drug Targets
September 2024
Background: The use of herbal remedies, medicinal plants, and their derivatives for the treatment and control of hypertension is well-known and widespread throughout Morocco.
Aims: The aim of the study was to review the antihypertensive and vasorelaxant medicinal plants of the Moroccan pharmacopeia.
Objective: To date, no review on Moroccan medicinal plants exhibiting antihypertensive effects has been performed, and their mechanism of action has not been specified.
Cardiovasc Hematol Disord Drug Targets
January 2024
Aims: This work aimed to investigate the antihypertensive activity of Ammi visnaga.
Background: The aqueous extract of Ammi visnaga has traditionally been used to treat hypertension in Morocco.
Objective: The objective of this investigation was to evaluate the effect of Ammi visnaga aqueous extract (AVAE) on arterial blood pressure, systolic blood pressure (SBP), mean blood pressure (MBP), diastolic blood pressure (DBP), and heart rate (HR) in normotensive and hypertensive rats.
Aims: The purpose of this review was to emphasize the nutritional value, and pharmacological and phytochemical properties of , as well as its toxicological evaluation.
Background: Salvia hispanica L. (), also called chia seeds, is an annual herbaceous plant belonging to the family Lamiaceae.
The species L. ( L.) belongs to the family Lamiaceae, native to Europe, North Africa, and the Middle East, and the genus .
View Article and Find Full Text PDFCardiovasc Hematol Disord Drug Targets
December 2023
Aim: The current study aimed to evaluate the antidiabetic potential of Illicium verum fruits.
Background: Illicium verum fruits are frequently used by the Moroccan population in the treatment of diabetes.
Methods: The antihyperglycemic effect of the aqueous extract of Illicium verum fruits (AEIVF) in rats was assessed.
Endocr Metab Immune Disord Drug Targets
January 2024
has been largely used in traditional medicine. This study aims to review the pharmacological and phytochemical properties of L and also summarize the pharmacological, photochemical, and toxicological characteristics of . The current review focuses on the distribution, chemical content, and main uses of .
View Article and Find Full Text PDFCardiovasc Hematol Disord Drug Targets
March 2023
Background: Traditionally, the aerial parts of Rhamnus alaternus L. have been widely used in Mediterranean countries, including Morocco, to cure diabetes.
Aim: This study aimed to evaluate the antidiabetic effect of Rhamnus alaternus aqueous extract in streptozotocin(STZ)-induced diabetic rats.
Cardiovasc Hematol Agents Med Chem
June 2023
Background: is a medicinal plant used in traditional medicine to treat various ailments, including hypertension.
Aims: The study aimed to determine the antihypertensive activity of .
Objective: The study aimed to investigate the antihypertensive and vasorelaxant activities of the aqueous extract of fruits (ALAE) in rats.
Cardiovasc Hematol Agents Med Chem
March 2023
Aims: The work aimed to study the antihypertensive ability of Haloxylon scoparium.
Background: Haloxylon scoparium Pomel is used to treat various diseases, including hypertension.
Objective: This study aimed to evaluate the antihypertensive effect of Haloxylon scoparium (H.
Curr Top Med Chem
September 2022
Ethnopharmacological Relevance: Plants of the genus Euphorbia have long been used as traditional medicine in China, Europe, America, Turkey, India, Africa, Iran, and Pakistan for their great medicinal value and health benefits. Their stems, leaves, roots, and latex are widely used to treat respiratory infections, body and skin irritations, digestive disorders, inflammatory infections, body pain, snake or scorpion bites, pregnancy, sensory disturbances, microbial and anticancer diseases.
Objectives: This review aims to provide updated information on the genus Euphorbia, including traditional medicinal uses, valuation and exploitation of medicinal plants, phytochemistry, botanical characterization, pharmacological and toxicological research focused on the medicinal properties of several Euphorbias in particular their antibacterial, anti-tumor, and cell manifestations, in addition to the effect of each isolated bioactive molecule from these species and their pharmacological use including preclinical evaluation of new drugs.