Publications by authors named "Sloane Mebane"
Objective: To evaluate cumulative live birth after preimplantation genetic testing for aneuploidy (PGT-A) with next generation sequencing (NGS) compared with morphology alone among patients aged 21-40 years undergoing single blastocyst transfer.
Design: Retrospective cohort study.
Setting: Society for Assisted Reproductive Technology (SART) clinics.
Article Synopsis
- The study aimed to assess how donor gamete utilization, patient satisfaction, and fertility outcomes vary based on the race and ethnicity of both the patients and their chosen gamete donors at a Southeastern U.S. fertility clinic from 2015 to 2020.
- Out of 450 patients eligible, 170 participated; findings showed that 59% preferred non-Hispanic White donors, with those preferring non-Hispanic Black donors facing significantly lower usage rates (OR 0.13) and satisfaction levels (OR 0.19).
- The results indicated that both non-Hispanic Black patients and those using non-Hispanic Black donors had notably lower chances of successful conception (OR
Family building is a human right. The high cost and lack of insurance coverage associated with fertility treatments in the United States have made treatment inaccessible for many patients. The universal uptake of "add-on" services has further contributed to high out-of-pocket costs.
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- - The study aimed to evaluate recall bias among female cancer survivors regarding their cancer diagnosis, treatment, and fertility preservation (FP) counseling, highlighting a gap in understanding this bias.
- - A survey conducted with 117 female oncology patients found that many struggled to remember details about their chemotherapy regimens and reported low awareness of FP counseling despite documentation.
- - Results indicated poor recall of key treatment discussions, with more than a third of patients not remembering documented FP counseling, emphasizing the need for better follow-up and communication in oncology care.
Repetitive head injury in adolescent mice: A role for vascular inflammation.
J Cereb Blood Flow Metab
November 2019
Repetitive mild traumatic brain injury during adolescence can induce neurological dysfunction through undefined mechanisms. Interleukin-1 (IL-1) contributes to experimental adult diffuse and contusion TBI models, and IL-1 antagonists have entered clinical trials for severe TBI in adults; however, no such data exist for adolescent TBI. We developed an adolescent mouse repetitive closed head injury (rCHI) model to test the role of IL-1 family members in post-injury neurological outcome.
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