Short-term postoperative distress associated with open vs. transoral robotic surgery (TORS) in patients with T1-T2 carcinomas of the tongue base and supraglottis.

Background: This study compared the adverse effects of open surgery (OS) including lateral pharyngotomy and supraglottic laryngectomy vs. transoral robotic surgery (TORS) in the treatment of stage T1 and T2 carcinomas of the tongue base and supraglottis.

Methods: A retrospective study involving a 49 (13 female and 36 male) patients with untreated T1 or T2 carcinomas.

The head problem. The organizational significance of segmentation in head development.

This review argues for the segmental basis of chordate head organization which, like somite-based segmental organization in the trunk, takes its origin from early mesodermal development. The review builds on, and brings up to date, Goodrich's well-known scheme of head organization. It surveys recent data in support of this scheme and shows how evidence and arguments supposedly in conflict with it can be accommodated.

[Free radicals and antioxidants in otorhinolaryngology].

Free radicals in otorhinolaryngology participate in the pathogenesis of many diseases. Antioxidants can act or preventively or ameliorate the diseases. Oxidative stress, in which is the predominance of free radicals to antioxidants, is present in many states like inflammation, atherosclerosis or tumors.

Developmental relation between palatine tonsils and kidney.

The evolutionary changes of the immune process in the whole line of representatives of the organisms were followed. The immune organs responsible for processing the antigens evolved from the derivatives of coelomic lining over the gut folds to the immune organs developed in the gill region of the digestive tract. Among them the tonsils have to be considered as a very modern evolutionary immune organ.

Congenitally determined neurodegeneration "Lurcher" induces morphofunctional changes of thymus.

A significantly higher frequency of apoptosis was documented by flow cytometry and by ELISA analysis, and significantly higher numbers of necrotic cells were demonstrated by ELISA within the thymus of Lurcher mice in comparison with the control C3H mice. These can be regarded as important markers of degenerative changes in this primary immune organ. This tendency is supported by histological observation of the absence of a clear interface between thymic cortex and medulla and an insignificantly increased number of Hassall's corpuscles resembling an onset of thymic atrophy.

The palatine tonsil as an evolutionary novelty.

The development of the pharyngeal pouches was studied in early human embryos. A vesicular thymus primordium, separated from the lining epithelium of the second pouch, is described in 5-week-old embryo's (9 mm stage). This transitory structure disappeared in the next stage (10 mm).

Development of the pharynx in normal and malformed fetuses.

We studied the development of the pharynx in human embryos and fetuses. Embryos and fetuses from 4.5 mm crown-rump length (CRL) to 40 mm CRL were processed for microscopic examination.

The segmental Bauplan of the rostral zone of the head in vertebrates.

Observations in a wide selection of lower vertebrate embryos have confirmed classical descriptions concerning segmentation of the early head mesoderm. The premandibular (PM) segment is seen as the most rostral representative of a continuous rostro-caudal series of condensations in the paraxial mesoderm, luminisations within which are secondary and variable in occurrence and form. The premandibular condensations are typically in continuity across the midline; the confluence, which comes to lie behind Rathke's pouch, marks the site of first mesoderm formation behind the oral membrane.

Formation of the tonsillar corpuscle.

In this study of the human palatine tonsil we examined epithelial structures found always in the vicinity of the crypts and closely resembling thymic Hassall's corpuscles. We propose that in the reactive tonsillar lymphoid tissue these corpuscles form as a result of occlusion of fine microcrypts by the expanding lymphoid follicles during antigenic stimulation. The reticulated epithelial cells lining these microcrypts may then loose their polarisation, and gradually degenerate deep in the parenchyma, forming concentrically arranged parakeratotic pearls, rather than desquamate at the free epithelial surface.

Repeated antigenic challenge induces earthworm coelomocyte proliferation.

Annelids are able to protect themselves against foreign materials by natural and acquired cellular immunity. The aim of this study was to characterize the kinetic of antigen induced proliferation of earthworm coelomocytes. The proliferative activity of free coelomocytes of Eisenia foetida decreased after a second contact with the same antigen.

Analytical morphometry of sagittal fronto-facial profiles of 2nd-6th month human foetus.

A prominent problem in the morphological study of developing biological structures is shape parametrization with the aim to evaluate transformations in a non subjective way. We carried out an analytical morphometrical study on a series of human embryos, by means of the S.A.

[An unusual early complication of tonsillectomy].

The authors describe the observation of a localized tissue emphysema of the right cheek, which developed in an eight-year-old child as the early complication of tonsillectomy performed under local anaesthesia. In addition to reflections on the possible pathways of the gas from the tonsillar bed into interstitial spaces of the cheek, the authors draw attention also to possible concurrent penetration into the soft tissues of the neck and mediastinum.

[Radiodiagnostic methods in the postmortem study of a dicephalus masculinus].

With conventional radiography and with CT several malformations were detected in a dicephalus masculinus. The most important were: 2 spinal medullas in a common spinal canal (TH1 to L4), hydrocephalus of both lateral ventricles and of the third ventricle, prolaps of the left hepatic lobe into the left thoracic cavity, two aortic arcs, one large internal jugular vein, and twin bases of the vertebrae TH1 to L5. The dicephalus had not only a double head, but also two cervices connected by a falx.

Palatine tonsils--their evolution and ontogeny.

The structure of the palatine tonsils in an evolutionary line of mammals and its development in man was studied. The homologies between the thymus and tonsils were pointed out. Both primordia come from the same source and their epithelium reticulizes and can form concentric corpuscles.