Parapontine epidermoid tumours presenting as trigeminal neuralgias: anatomical findings and operative results.

Four cases of medically intractable trigeminal neuralgia caused by parapontine epidermoid tumours are reported. All patients presented with typical trigeminal neuralgia and low-density area in the parapontine region on CT-scans. Neurologically in all cases slight hypaesthesia in various divisions of the trigeminal nerve without other neurological signs was revealed.

Mixed lymphocyte reactions for individuals with phenotypic identity for specific HLA-B,DR determinants: the role of linkage disequilibrium and of specific DR and other class II determinants.

Although many patients who might benefit from therapeutic bone marrow transplantation lack HLA identical sibling donors, results from many centers now indicate that transplants involving donors other than identical siblings have been successful in a substantial number of cases. Most of these cases were selected because cells from the patient and donor were compatible in mixed lymphocyte culture. We have previously shown that the prediction of mixed lymphocyte culture nonreactivity by HLA-B,DR matching is far more successful if the matched donors shared antigen combinations known to possess significant positive linkage disequilibrium.