Correlation of demographic, histological and molecular characteristics and clinical course of the disease in patients with lung adenocarcinoma.

Aim Retrospective analysis of disease clinical course with a purpose of defining potential prognostic parameters which are essential for optimal target therapy. Methods The study involved 29 patients with histologically confirmed lung adenocarcinoma and existing epidermal growth factor receptor (EGFR) mutations, which are treated by tyrosine kinase inhibitors (TKI). Results Allegations of a larger prevalence in women and non-smokers were found.