Publications by authors named "Skhodkina N"

Toxicologic characteristics of anti-tumor medication lisomustine. The authors presented materials on experimental studies of toxicity and jeopardy to justify hygienic regulation of workplace air for antitumor medication lisomustine: data on acute toxicity, results of irritative, resorptive and sensitizing effects evaluation, mutagenous and cumulative effects, influence on reproduction.

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The authors present materials on experimental basis of approximate safe level of exposure to new anti-flu medication Triazavirin in air of workplace. The article covers acute toxicity parameters for various intake routes, results of irritating and sensitizing effects evaluation, determination of threshold concentration for single inhalation effect, value of recommended approximate safe level of exposure.

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The article contains to forecast risk of toxic effects caused by contemporary household chemicals. The article contains data on evaluating potential risk of health disorders among individuals contacting synthetic detergents and cleansers. The authors summarized experience of Public Health Research center on toxicologic hygienic research of various household chemicals, conducted for safety certification of the end products household application.

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The authors justify importance of biologic monitoring to increase quality of hygienic control over and diagnosis of occupational disease. The article covers data on international terminology for exposure tests parameters. Although difficult in elaboration, the exposure tests are highly informative and necessary to be put into practice.

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The authors present materials on hygienic regulation of such synthetic detergents as "Losk", "Dixan" in air of workplace and populated area, demonstrate results concerning evaluation of "Losk" effects. Discussion covers ways to evaluate chemical load caused by simultaneous emission of synthetic detergents from various environmental objects. For testing reliability of hygienic regulation for complex emission exemplified by "Losk", the authors suggest a model for express evaluation of complex exposure to chemicals.

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Experiments on animals were conducted to study influence of following household chemical components included into synthetic washing and cleaning mixtures: anion-active surface active substances, protease Blap 200 G, Savinase 4.OT, Purafect 200 G, alkaline proteinase made in Russia, an aromatic "Magic blue". Surface active substances included into synthetic washing and cleaning mixtures were proved to increase biologic activity of chemical components of the mixtures.

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