Publications by authors named "Skelly L"

We examined postprandial branched-chain amino acid (BCAA), insulin, and glucose responses in blood for 4 h following the consumption of two isonitrogenous doses (2 × 20 g protein) of Greek-style yogurt (GY) and skimmed milk (MILK) in young males. Peak leucine and BCAA concentrations and areas under the curve were greater after GY versus MILK, and time to maximal leucine/BCAA concentrations was similar between conditions. We demonstrated that different protein-matched wholefood dairy products elicit different postprandial aminoacidemic responses.

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Article Synopsis
  • There is growing interest in how interval (INT) training compares to continuous (CONT) training in enhancing mitochondrial content in skeletal muscles, especially considering factors like exercise intensity and individual differences.
  • A study involving 10 young adults used a single-leg cycling approach to investigate whether short-term INT training would lead to greater mitochondrial improvements than CONT training, while keeping total volume and intensity equal.
  • Results showed that CONT training significantly increased markers of mitochondrial content, whereas INT training did not, even though both training methods improved muscle performance.
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Exercise and consumption of dairy foods have been shown to improve bone mineralization. However, little is known about the magnitude and timing of their synergistic effects on markers and regulators of bone metabolism in response to acute exercise in adolescent females with obesity, a population susceptible to altered bone metabolism and mineral properties. This study examined the influence of twelve weeks of exercise training and nutritional counselling on the bone biochemical marker response to acute exercise and whether higher dairy consumption could further influence the response.

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As Open Science (OS) is being promoted as the best avenue to share and drive scientific discoveries at much lower costs and in transparent and credible ways, it is imperative that African governments and institutions take advantage of the momentum and build research infrastructures that are responsive to this movement. This paper aims to provide useful insight into the importance and implementation of OS policy frameworks. The paper uses a systematic review approach to review existing literature and analyse global OS policy development documents.

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High-intensity/impact exercise elicits a transient increase in inflammatory biomarkers. Consuming nutrient-dense wholefoods, like milk, following exercise may modulate post-exercise inflammation and aid recovery. We examined the effect of post-exercise skim milk consumption (versus an isoenergetic, isovolumetric carbohydrate [CHO] drink) on acute exercise-induced inflammation in untrained females.

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Our study examined how increased dairy consumption versus habitually low dairy consumption, against a background of healthy eating (and exercise), influenced diet quality, nutrient intake, and snacking in Canadian female adolescents (14.8 ± 2.2 years) with overweight/obesity (OW/OB).

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A key motivation for Open Science is accessibility. For researchers in resource-poor economies, this translates into access to the methods, data and publications that will foster scientific research and discovery in such communities and environments. Attitudes toward Open Science are in flux, and there is a growing awareness of the roles and responsibilities that researchers have to one another in this regard.

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Dairy products and impact exercise have previously been identified to be independently beneficial for bone mineral properties, however, it is unknown how the combination of these two osteogenic interventions may alter acute bone turnover. Using a randomized crossover design, we compared the acute effects of consuming milk vs. an isoenergetic carbohydrate control beverage on bone biomarkers following loading exercise.

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Dairy products can act as a dietary source of lithium (Li), and a recent study in university-aged males demonstrated that Greek yogurt (GY) supplementation augmented gains in fat free mass, strength and bone formation after 12 weeks of resistance exercise training compared to carbohydrate (CHO) pudding supplementation. Here, we performed secondary analyses to explore whether GY would alter serum Li levels and whether changes in serum Li would associate with changes in body composition, strength, and bone turnover markers. Results show that the GY group maintained serum Li levels after exercise training, whereas the CHO group did not.

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Interval training is a form of exercise that involves intermittent bouts of relatively intense effort interspersed with periods of rest or lower-intensity exercise for recovery. Low-volume high-intensity interval training (HIIT) and sprint interval training (SIT) induce physiological and health-related adaptations comparable to traditional moderate-intensity continuous training (MICT) in healthy adults and those with chronic disease despite a lower time commitment. However, most studies within the field have been conducted in men, with a relatively limited number of studies conducted in women cohorts across the lifespan.

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The presence of obesity and some cardiometabolic disease risk factors in childhood and adolescence track into adulthood. Intake of dairy products has been shown to be inversely related to adiposity and cardiometabolic variables in youth. However, limited research has examined cardiometabolic disease risk factors following increased dairy product consumption as part of a lifestyle modification intervention in youth with overweight/obesity.

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Article Synopsis
  • There is limited research on how different types of muscle fibers in humans respond to sprint interval training (SIT) compared to moderate-intensity continuous training (MICT).
  • A study analyzed fiber-specific responses to both training methods, assessing signaling proteins and mitochondrial content over a single session and 12 weeks.
  • Results showed that while both training methods induced similar changes in signaling proteins, only MICT significantly increased mitochondrial markers in type I fibers after training.
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Background: People with intellectual disabilities are more at risk of obesity than the general population. Emerging literature indicates that multicomponent interventions are most effective, however, individual results are variable and little research exists as to why this is the case.

Methods: Focus groups were conducted to explore lived experiences between two groups of adults with intellectual disabilities; an overweight group ( = 6) and a group identified as successful in losing weight ( = 6).

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  • Previous research indicated low levels of neuroplasticity from acute exercise in low-fit individuals, but the effects of exercise intensity were not well understood.
  • This study examined the impact of high-intensity (HI) and moderate-intensity (MOD) interval exercise on neuroplasticity using transcranial magnetic stimulation (TMS) in a group of low-fit individuals (n = 19).
  • Results showed no significant changes in corticospinal excitability after either HI or MOD exercise, suggesting that acute workouts don't enhance neuroplasticity in sedentary, young individuals, and that consistent training may be needed for such changes.
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The legs of 9 men (age 21 ± 2 years, 45 ± 4 mL/(kg·min)) were randomly assigned to complete 6 sessions of high-intensity exercise training, involving either one or four 5-min bouts of counterweighted, single-leg cycling. Needle biopsies from vastus lateralis revealed that citrate synthase maximal activity increased after training in the 4-bout group ( = 0.035) but not the 1-bout group ( = 0.

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The aim of this study was to evaluate if prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) has a higher detection rate compared to standard contrast CT imaging for patients with a rising prostate-specific antigen (PSA) following definitive treatment (i.e., curative radical prostatectomy, radiotherapy, and brachytherapy) for prostate cancer in a private hospital setting.

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Acute aerobic exercise induces short-term neuroplasticity, although it remains unknown whether biological sex and ovarian hormones influence this response. The present study investigated the effects of biological sex and ovarian hormones on short-term neuroplasticity induced by acute aerobic exercise. Young active adults (n = 17 males and n = 17 females; 21 ± 2 years) participated in two sessions in which transcranial magnetic stimulation (TMS) measures were acquired immediately before and after a 20-min bout of moderate-intensity cycling at 65-70% of maximal heart rate.

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We investigated the effect of stair climbing exercise "snacks" on peak oxygen uptake. Sedentary young adults were randomly assigned to perform 3 bouts/day of vigorously ascending a 3-flight stairwell (60 steps), separated by 1-4 h of recovery, 3 days/week for 6 weeks, or a nontraining control group ( = 12 each). Peak oxygen uptake was higher in the climbers after the intervention ( = 0.

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Proper germ cell sex determination in Caenorhabditis nematodes requires a network of RNA-binding proteins (RBPs) and their target mRNAs. In some species, changes in this network enabled limited XX spermatogenesis, and thus self-fertility. In C.

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New Findings: What is the central question of this study? What is the acute brachial artery endothelial function response to sprint interval exercise and are there sex-based differences? What is the main finding and its importance? Brachial artery endothelial function did not change in either men or women following an acute session of SIT consisting of 3 × 20 s 'all-out' cycling sprints. Our findings suggest this low-volume protocol may not be sufficient to induce functional changes in the brachial artery of sedentary, but otherwise healthy adults.

Abstract: Sprint interval training (SIT) is a potent metabolic stimulus, but studies examining its acute effects on brachial artery endothelial function are limited.

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Objectives: This retrospective study aimed to evaluate the role of Ga-PSMA-I&T PET/CT in the primary staging of newly diagnosed prostate cancer (PCa), with a focus on the detection of metastatic nodal disease. Correlation of the rate of detection of metastatic disease by Ga-PSMA-I&T PET/CT with the Gleason score (GS) and serum prostate-specific antigen (PSA) was performed to determine the GS and PSA criteria defining patients who would benefit from Ga-PSMA-I&T PET/CT imaging for staging, risk stratification and therapy optimization.

Patients And Methods: Patient data and images from 70 patients with a recent diagnosis of prostate cancer who had undergone Ga-PSMA-I&T PET/CT were analysed retrospectively.

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