Publications by authors named "Sjoerd Driessen"
CNN-Based Device-Agnostic Feature Extraction From ONH OCT Scans.
Transl Vis Sci Technol
December 2024
Purpose: Optical coherence tomography (OCT)-derived measurements of the optic nerve head (ONH) from different devices are not interchangeable. This poses challenges to patient follow-up and collaborative studies. Here, we present a device-agnostic method for the extraction of OCT biomarkers using artificial intelligence.
View Article and Find Full Text PDFImportance: Primary open-angle glaucoma (POAG) polygenic risk scores (PRSs) continue to be evaluated in primarily European-ancestry populations despite higher prevalence and worse outcomes in African-ancestry populations.
Objective: To evaluate how established POAG PRSs perform in African-ancestry samples from the Genetics in Glaucoma Patients of African Descent (GIGA), Genetics of Glaucoma in Individuals of African Descent (GGLAD), and Million Veteran Program (MVP) datasets and compare these with European-ancestry samples.
Design, Setting, And Participants: This was a multicenter, cross-sectional study of POAG cases and controls from Tanzania, South Africa, Nigeria, Ghana, and the US.
Article Synopsis
- Atropine is identified as the most effective treatment for slowing down progressive myopia in children and this study assesses its effectiveness over a 3-year clinical period.
- The study involved 124 children, with adjustments made to the atropine dosage based on individual responses to treatment, highlighting a significant portion of participants remained on the medication throughout the study.
- The results indicate that those treated with atropine 0.5% experienced reduced myopia progression, supporting its use as a viable option for managing high myopia risk in children.