Prevalence of Hyponatremia in Hypothyroid Patients during Radioactive ¹³¹I Ablation for Differentiated Thyroid Cancer: Single Institution Experience.

Background: Hyponatremia developing in hypothyroid patients has been encountered in clinical practice; however, its prevalence has not been well established.

Methods: Thirty patients diagnosed with differentiated thyroid cancer, rendered hypothyroid after surgery and levothyroxine withdrawal, and who are for radioactive iodine (RAI) ablation were included. Serum sodium concentrations were measured twice, at the time of admission for RAI ablation, and before discharge after increased oral fluid intake.

Coexistence of malignant struma ovarii and Graves' disease.

Objective: To report an unusual case of hyperthyroidism from Graves' disease that was coexistent with malignant struma ovarii.

Methods: We summarize the clinical history, physical findings, laboratory data, imaging studies, pathologic features, and treatment in a patient with recurrent hyperthyroidism and discuss the incidence of ovarian tumors of various histologic origins, including thyroid tissue (that is, struma ovarii).

Results: Five years after diagnosis of Graves' disease and resolution of symptoms with 1 year of antithyroid drug therapy, a 53-year-old woman had recurrence of palpitations, tremors, and weight loss.

Cushing's disease after surgical resection and radiation therapy for nonfunctioning pituitary adenoma.

Objective: To describe a patient with an aggressive nonfunctioning pituitary adenoma in whom Cushing's disease developed after two resections of tumor and radiation therapy.

Methods: We present a case report, with serial laboratory and immunohistochemical data, and summarize information about similar patients described in the medical literature.

Results: A 48-year-old woman had irregular menstrual periods, decreased peripheral vision, headaches, and weight gain.