Discriminative detection of various organophosphorus nerve agents and analogues based on self-trapping probe coupled with SERS.

Organophosphorus nerve agents (OPNAs) are highly lethal chemical warfare agents (CWAs), which poses a serious threat to human health and safety. The accurate and rapid identification of OPNAs is crucial for medical diagnosis and effective treatment. However, distinguishing between various OPNAs and their analogues using on-site point-of-care testing (POCT) remains challenging.