Publications by authors named "Siyun Joung"
Adv Sci (Weinh)
October 2024
Article Synopsis
- The development of effective cell lines for therapeutic protein production is critical, but traditional glutamine-based selection methods have shortcomings in efficiency and flexibility.
- Researchers created a new selection system called SiMPl-GS, which uses a split intein-mediated protein ligation approach to enhance cell survival in glutamine-free environments.
- SiMPl-GS not only improves the selection of high-producing cells but also allows for the simultaneous selection of multiple plasmids, making the cell line development process faster and more efficient.
