Publications by authors named "Siyue Wang"

The cicada genus Mata Distant, 1906 was reviewed based on the description of one new species, Mata uncinulata sp. nov., from China.

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Multiple gastrointestinal disorders are associated with impaired gut microbiota. Probiotic can improve bowel disorder, however, the action mechanism is poorly understood. We integrated multi-omics data from the gut metagenome, metabolome, and colon transcriptome of constipated mice underlying LRJ-1 treatment to provide insights into host-microbial metabolic pathway.

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Article Synopsis
  • * Results showed that higher CRP levels were significantly associated with increased T2D risk, with hazard ratios indicating a clearer risk pattern across progressively higher CRP levels.
  • * Additionally, the relationship between CRP levels and T2D risk was stronger in participants with poor sleep quality, highlighting the interaction between inflammation and sleep issues.
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Background: The projection indicates that compound drought and hot events (CDHEs) will intensify, posing risks to cardiovascular health by potentially increasing stroke incidents. However, epidemiological evidence on this topic remains scarce. This study investigates the association between exposure to CDHEs and the risk of daily stroke admissions, specifically examining the effects on various stroke categories such as Subarachnoid Hemorrhage (SAH), Intracerebral Hemorrhage (ICH), Ischemic Stroke (IS), Transient Ischemic Attack (TIA), and other types of stroke.

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Objective: To delve into the intricate relationship between common genetic variations across the entire genome and the risk of non-syndromic cleft lip with or without cleft palate (NSCL/P).

Methods: Utilizing summary statistics data from genome-wide association studies (GWAS), a thorough investigation to evaluate the impact of common variations on the genome were undertook. This involved assessing single nucleotide polymorphism (SNP) heritability across the entire genome, as well as within specific genomic regions.

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Previous evidence on heatwaves' impact on mental health outpatient visits is limited, especially uncertainty on how different heatwave definitions affect this relationship. In this time-series study, we assessed the association between heatwaves and outpatient visits for mental disorders in Guangzhou, China. Daily outpatient visits for mental disorders and its specific categories (schizophrenia, mood, and neurotic disorders) were sourced from the Urban Resident-based Basic Medical Insurance (URBMI) and the Urban Employee-based Basic Medical Insurance (UEBMI) claims databases in Guangzhou from 2010 to 2014.

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Aim: To assess the association between Benzodiazepines (BZDs) or Z-hypnotic use and cardiovascular diseases (CVD) incidence in residents in Beijing, China.

Methods: We included 2,415,573 individuals with a prescription record for BZDs or Z-hypnotics in the Beijing Medical Claim Data for Employees database during 2010-2017, and 8,794,356 non-users with other prescriptions for the same period. Hazard ratios (HR) and 95% confidence intervals (CI) were calculated using Cox proportional risk models for 712,850 exposed and 712,850 unexposed participants who were matched 1:1 by propensity score.

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Article Synopsis
  • The American Heart Association created Life's Essential 8 (LE8) to help people understand how to stay healthy and avoid heart problems.
  • A study looked at over 100,000 people and found that following LE8 can lower the risk of getting high blood pressure and heart diseases.
  • The results showed that better scores in LE8 were linked to a lower chance of moving from being healthy to getting sick or even dying, highlighting the importance of following these health tips.
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The application of carbon fiber in cement matrix has some disadvantages, such as poor dispersion and poor interfacial adhesion. In order to improve the interaction between carbon fiber and cement matrix and improve the properties of cement-based composites, carbon fiber was modified by electrophoretic deposition of nano-graphene oxide (GO). In this paper, the effects of doping CF into the cement matrix before and after GO modification are studied comparatively in terms of electrical conductivity, electrothermal warming effect, and pressure-sensitive properties of the cement matrix.

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  • Lignans are natural compounds found in many Western diets, thought to potentially lower the risk of developing type 2 diabetes (T2D).
  • This study analyzed data from over 201,000 participants across multiple health studies to explore the relationship between lignan intake and T2D incidence over several decades.
  • Results indicated that higher lignan consumption was linked to a lower risk of T2D, showing particular promise except for one type, lariciresinol, with the highest versus lowest quintile of intake yielding a hazard ratio of 0.87.
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  • * Findings reveal that individuals carrying the rs10830963-G and rs1387153-T alleles have a significantly higher risk of IS, with each additional allele increasing risk by 36% and 32% respectively.
  • * Importantly, the study shows that adopting a healthier lifestyle can reduce the impact of these genetic risk factors, suggesting that a better lifestyle score leads to a decreased association between the gene variants and IS risk.
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Proto-oncogenic MYC is frequently dysregulated in colorectal cancer (CRC). In the past decades, long noncoding RNAs (lncRNAs) have emerged as important regulators in cancers, acting as scaffolds, molecular decoys, post-transcriptional regulators, and others. Interestingly, lncRNAs are able to control MYC expression both at transcriptional and post-transcriptional levels.

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As a new type of artificial enzyme, a nanozyme is an ideal substitute for natural enzymes and has been successfully applied in many fields. However, in the application of biomolecular detection, most nanozymes have the disadvantages of long reaction times or high detection limits, prompting researchers to search for new efficient nanozymes. In this work, the enzyme-like activities of three polyoxometalate-based iron-organic complexes ([Fe(bpp)](MoO), [Fe(bpp)](MoO)·2CHOH, and [Fe(bpp)]H[Na(MoO)]), namely, FeMo, FeMo, and FeMoNa, were analyzed.

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Objective: To explore the association between polymorphisms of transforming growth factor-β (TGF-β) signaling pathway and non-syndromic cleft lip with or without cleft palate (NSCL/P) among Asian populations, while considering gene-gene interaction and gene-environment interaction.

Methods: A total of 1 038 Asian NSCL/P case-parent trios were ascertained from an international consortium, which conducted a genome-wide association study using a case-parent trio design to investigate the genes affec-ting risk to NSCL/P. After stringent quality control measures, 343 single nucleotide polymorphism (SNP) spanning across 10 pivotal genes in the TGF-β signaling pathway were selected from the original genome-wide association study(GWAS) dataset for further analysis.

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Objective: To explore the effects of short-term particulate matter (PM) exposure and the melatonin receptor 1B () gene on triglyceride-glucose (TyG) index utilizing data from Fang-shan Family-based Ischemic Stroke Study in China (FISSIC).

Methods: Probands and their relatives from 9 rural areas in Fangshan District, Beijing, were included in the study. PM data were obtained from fixed monitoring stations of the National Air Pollution Monitoring System.

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Importance: Plant-based diets are increasing in popularity due, in part, to their health benefits for selected cardiometabolic diseases as well as favorable environmental impact. Little is known about how such a diet is related to gout risk.

Objective: To examine associations between adherence to a plant-based diet (including healthy and unhealthy versions of this diet), as well as its 18 individual food groups, and incident gout.

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Nature-inspired supramolecular self-assemblies are attractive photocatalysts, but their quantum yields are limited by poor charge separation and transportation. A promising strategy for efficient charge transfer is to enhance the built-in electric field by symmetry breaking. Herein, an unsymmetric protonation, N-heterocyclic π-conjugated anthrazoline-based supramolecular photocatalyst SA-DADK-H was developed.

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Hydrogen peroxide (HO) is relatively stable among ROS (reactive oxygen species) and could act as a signal in plant cells. In the present work, detached tomato leaves were treated with exogenous HO at 10 mmol/L for 8 h to study the mechanism of how HO regulates leaf senescence. The data indicated that HO treatment significantly accelerated the degradation of chlorophyll and led to the upregulation of the expression of leaf senescence-related genes (, , , , and ) during leaf senescence.

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The dynamic genetic architecture of flowering time in chrysanthemum was elucidated by GWAS. Thirty-six known genes and 14 candidate genes were identified around the stable QTNs and QEIs, among which ERF-1 was highlighted. Flowering time (FT) adaptation is one of the major breeding goals in chrysanthemum, a multipurpose ornamental plant.

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Objective: The objective of this study is to investigate the gene-gene interactions associated with NSCL/P among DNA repair genes.

Design: This study included 806 NSCL/P case-parent trios from China. Quality control process was conducted for genotyped single nucleotide polymorphisms (SNPs) located in six DNA repair genes (, , , , and ).

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Endoplasmic reticulum (ER) stress plays a key role in the pathogenesis of several organ damages. Studies show that excessive ER stress (ERS) can destroy cellular homeostasis, causing cell damage and physiological dysfunction in various organs. In recent years, Sirtuin1 (SIRT1) has become a research hotspot on ERS.

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Background: Strategies to stabilize and support overall infant health by increasing the number of in the infant gut are of interest, but few studies have systematically addressed this issue. We aimed to evaluate the efficacy and safety of use in infants using meta-analysis.

Methods: We searched PubMed, EMBASE, Cochrane Library of Systematic Reviews, and SinoMed for publications until 27 July 2022.

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(1) Background: Previous studies suggest that exposure to nitrogen dioxide (NO) has a negative impact on health. But few studies have explored the association between NO and blood lipids or fasting plasma glucose (FPG), as well as gene-air pollution interactions. This study aims to fill this knowledge gap based on a pedigree cohort in southern China.

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Background: Implementing training programs to educate patients on the prodromal symptoms of acute coronary syndrome (ACS) may assist patients in accurately recognizing these symptoms, and ultimately decrease their time delay in seeking emergency medical services (EMS). However, the effectiveness of this approach remains uncertain, particularly among the Chinese population.

Methods: A cross-sectional study was conducted within 22 communities in Beijing, China between 2015 and 2018, with a total of 1099 participants recruited.

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Article Synopsis
  • - A multi-locus genome-wide association study (GWAS) on 200 chrysanthemum accessions identified genes linked to flowering time traits, which are crucial for reproduction and economic value in ornamental horticulture.
  • - The study recorded 10 flowering time traits, revealing significant genetic variation and stable quantitative trait nucleotides (QTNs) that account for a notable percentage of flowering time variation.
  • - Findings suggest that genomic selection models can accurately predict flowering traits, with the best prediction accuracy from significant SNPs showing potential to enhance chrysanthemum breeding efforts.
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