Genome-Wide Analysis of the Metallocarboxypeptidase Inhibitor Family Reveals That Affects Root Development and Tropane Alkaloid Production in .

is a medicinal plant and an important source for the commercial production of tropane alkaloids (TAs), such as scopolamine and hyoscyamine, which are used clinically for their anticholinergic properties. In this study, we identified 16 metallocarboxypeptidase inhibitor (MCPI) genes from (), which are grouped into three subgroups based on phylogenetic relationships and are distributed across 10 chromosomes. Promoter analysis showed that most elements were related to defense and stress responses, such as drought, low-temperature, ABA (abscisic acid), GA (gibberellin), auxin, light and MeJA responsiveness.

Dual-channel asymmetric absorption-transmission properties based on plasma metastructures-photonic crystals.

In this paper, a kind of plasma metastructures-photonic crystals (PMPC) structure is proposed to investigate the absorption and transmission properties of electromagnetic waves (EWs) incident from opposite directions. The results show that the PMPC can achieve a dual-channel asymmetric absorption-transmission (AAT) phenomenon. At an operating bandwidth (OB) of 2.

Dynamic hybrid parallel computing of the Ray Model for solving underwater acoustic fields in vast sea.

Utilizing acoustic information for search route planning will greatly increase the success rate of searching for underwater targets, which requires rapid computing of numerous underwater acoustic fields. The efficiency of traditional computing methods is too low to meet the requirements of rapid applications. In this paper, a underwater multi-acoustic fields computing model is developed based on ray theory, and multi-level hybrid parallel computing strategies are designed based on the model characteristics, and a dynamic scheduling optimization algorithm at process level is introduced to solve the load imbalance problem.

Assessing terrestrial water storage dynamics and multiple factors driving forces in China from 2005 to 2020.

In the context of global warming, comprehending the dynamics of terrestrial water storage (TWS) and its responses to natural and anthropogenic factors is paramount for hydrological research and the management of water resources in China. This study utilized GRACE (Gravity Recovery and Climate Experiment)/GRACE-Follow On (GRACE-FO) satellite data to analyze terrestrial water storage across nine basins in China from 2005 to 2020 at multiple temporal and spatial scales. Subsequently, employing a Geographic detector model, potential influencing factors were identified, and an enhanced Geographically Weighted Regression (GWR) method was proposed for attributing changes in TWS in China.

Reversible Switching Between Microwave Absorption and EMI Shielding of VO Composite Foam.

Developing lightweight composite with reversible switching between microwave (MW) absorption and electromagnetic interference (EMI) shielding is promising yet remains highly challenging due to the completely inconsistent attenuation mechanism for electromagnetic (EM) radiation. Here, a lightweight vanadium dioxide/expanded polymer microsphere composites foam (VO/EPM) is designed and fabricated with porous structures and 3D VO interconnection, which possesses reversible switching function between MW absorption and EMI shielding under thermal stimulation. The VO/EPM exhibits MW absorption with a broad effective absorption bandwidth of 3.

A Liquid Crystal-Modulated Metastructure Sensor for Biosensing.

In this paper, a liquid crystal-modulated metastructure sensor (MS) is proposed that can detect the refractive index (RI) of a liquid and change the detection range under different applied voltages. The regulation of the detection range is based on the different bias states of the liquid crystal at different voltages. By changing the sample in the cavity that is to be detected, the overall electromagnetic characteristics of the device in the resonant state are modified, thus changing the position of the absorption peaks so that different RI correspond to different absorption peaks, and finally realizing the sensing detection.

Recognition, possible source, and risk assessment of organic pollutants in surface water from the Yongding River Basin by non-target and target screening.

Organic pollutants in aquatic environment could have important implications on pollution stress on aquatic organisms and even on the risk of human exposure. Thus, revealing their occurrence in aquatic environment is essential for water quality monitoring and ecological risk purposes. In this study, a comprehensive two-dimensional gas chromatography connected with time-of-flight mass spectrometry (GC × GC-TOF-MS) was applied, to enable non-target and target analysis of pollutants in the Yongding River Basin.

Enhancing the Chemical Stability of MXene Through Synergy of Hydrogen Bond and Coordination Bond in Aqueous Solution.

MXenes with unique physicochemical properties have shown substantial potential in electromagnetic interference (EMI) shielding. However, the chemical instability and mechanical fragility of MXenes has become a major hurdle for their application. Abundant strategies have been dedicated to improving the oxidation stability of colloidal solution or mechanical properties of films, which always come at the expense of electrical conductivity and chemical compatibility.

Switchable ultra-broadband absorption and polarization conversion metastructure controlled by light.

This article proposed a metastructure device that can realize polarization conversion (PC) and absorption function switching in the terahertz (THz) range based on the photoconductivity effect. The photoconductance is formed by exposing silicon to different intensities of light, then the PC and absorption function can be switched. At the same time, the absorption bandwidth is expanded by inserting air resonant cavities into the dielectric substrate, changing the thickness of the dielectric locally, and cutting rectangular slots at the metal bottom plate.

Metallized Skeleton of Polymer Foam Based on Metal-Organic Decomposition for High-Performance EMI Shielding.

Highly conductive polymer foam with light weight, flexibility, and high-performance electromagnetic interference (EMI) shielding is highly desired in the fields of aerospace, communication, and high-power electronic equipment, especially in the board-level packaging. However, traditional technology for preparing conductive polymer foam such as electroless plating and electroplating involves serious pollution, a complex fabrication process, and high cost. It is urgent to develop a facile method for the fabrication of highly conductive polymer foam.

Ultrathin Densified Carbon Nanotube Film with "Metal-like" Conductivity, Superior Mechanical Strength, and Ultrahigh Electromagnetic Interference Shielding Effectiveness.

Flexible and lightweight high-performance electromagnetic interference shielding materials with minimal thickness, excellent mechanical properties, and outstanding reliability are highly desired in the field of fifth-generation (5G) communication, yet remain extremely challenging to manufacture. Herein, we prepared an ultrathin densified carbon nanotube (CNT) film with superior mechanical properties and ultrahigh shielding effectiveness. Upon complete removal of impurities in pristine CNT film, charge separation in individual CNTs induced by polar molecules leads to strong CNT-CNT attraction and film densification, which significantly improve the electrical conductivity, shielding performance, and mechanical strength.

Astrocyte-derived VEGF increases cerebral microvascular permeability under high salt conditions.

Excess salt (NaCl) intake is closely related to a variety of central nervous system (CNS) diseases characterized by increased cerebral microvascular permeability. However, the link between a high salt diet (HSD) and the breakdown of tight junctions (TJs) remains unclear. In the present study, we found that high salt does not directly influence the barrier between endothelial cells, but it suppresses expression of TJ proteins when endothelial cells are co-cultured with astrocytes.

The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke.

Background: Preserving the integrity of the blood-brain barrier (BBB) is beneficial to avoid further brain damage after acute ischemic stroke (AIS). Astrocytes, an important component of the BBB, promote BBB breakdown in subjects with AIS by secreting inflammatory factors. The glucagon-like peptide-1 receptor (GLP-1R) agonist exendin-4 (Ex-4) protects the BBB and reduces brain inflammation from cerebral ischemia, and GLP-1R is expressed on astrocytes.

The influence of non-breathing-related sleep fragmentation on cognitive function in patients with cerebral small vessel disease.

Background: Cognitive impairment in patients with cerebral small vessel disease (CSVD) is common, but the pathogenic mechanism is not well understood. The situation of non-breathing-related sleep fragmentation in CSVD patients and its influence on cognitive impairment is not clear. The aim of this study was to investigate the influence of non-breathing-related sleep fragmentation on cognitive function in patients with CSVD.

Neutralization of interleukin-9 ameliorates experimental stroke by repairing the blood-brain barrier via down-regulation of astrocyte-derived vascular endothelial growth factor-A.

Astrocytes mediate the destruction of the blood-brain barrier (BBB) during ischemic stroke (IS). IL-9 is a pleiotropic cytokine that we previously found to be highly expressed in peripheral blood mononuclear cells from patients with IS, and the presence of IL-9 receptors on astrocytes has been reported in the literature. Here, we detected the effect of IL-9 on astrocytes using an anti-IL-9-neutralizing antibody to treat rats with experimental stroke.

Different Mechanisms of Two Subtypes of Perforating Artery Infarct in the Middle Cerebral Artery Territory: A High-Resolution Magnetic Resonance Imaging Study.

Perforating Artery Infarcts (PAIs) can be divided into two subtypes based on their etiologies: branch Atheromatous Disease (BAD) and Lacunar Infarct (LI). Recent studies have shown that while both subtypes can be caused by large artery lesions, the different mechanisms that underlie their development are not clear. This study was designed to use High-Resolution Magnetic Resonance Imaging (HRMRI) to explore the differences that contribute to the occurrence of these two subtypes in large artery lesions in the anterior circulation.

Cerebral small vessel disease: neuroimaging markers and clinical implication.

Cerebral small vessel disease (CSVD) is a broad category of cerebrovascular diseases which primarily affect the perforating arterioles, capillaries and venules with multiple distinct etiologies. In spite of distinctive pathogenesis, CSVD shares similar neuroimaging markers, including recent small subcortical infarct, lacune of presumed vascular origin, white matter hyperintensity of presumed vascular origin, perivascular space and cerebral microbleeds. The radiological features of neuroimaging markers are indicative for etiological analysis.

Serum 25-hydroxyvitamin D deficiency predicts poor outcome among acute ischemic stroke patients without hypertension.

25-Hydroxyvitamin D (25(OH)D) deficiency is a frequent condition in patients who suffer acute ischemic stroke (AIS), and several studies suggested that it may be associated with a poorer prognosis. Whether this association is affected by hypertension is unclear. Our aim was to investigate the association between 25(OH)D levels and both clinical severity and outcome after 3 months in AIS patients stratified by the history of hypertension.

Risk Factors and Clinical Manifestations of Juxtacortical Small Lesions: A Neuroimaging Study.

Background And Objective: White matter hyperintensities can be easily identified by brain imaging. Juxtacortical small lesion (JCSL) is a special type of white matter lesion, defined as no greater than 5 mm in diameter and adjacent to the cerebral cortex in location. We notice lately that JCSLs alone may be associated to various neurological symptoms.

Exacerbation of oxygen-glucose deprivation-induced blood-brain barrier disruption: potential pathogenic role of interleukin-9 in ischemic stroke.

Interleukin (IL)-9 exerts a variety of functions in autoimmune diseases. However, its role in ischemic brain injury remains unknown. The present study explored the biological effects of IL-9 in ischemic stroke (IS).

High salt-induced activation and expression of inflammatory cytokines in cultured astrocytes.

Salt (sodium chloride, NaCl) accumulation in the brain is associated with various diseases of central nervous system (CNS). Activation of astrocytes is an important manifestation of pathophysiological processes in the CNS. However, the direct impact of high salt (HS) environment on astrocytes is unclear.