In this study, smart films of EFS, EFS-SiO and EFS-SiO-CRE were successfully developed by using Euryale ferox starch (EFS), nano-SiO and Chinese rose extract (CRE). The Chinese rose flower had a high content of anthocyanins (1.73 mg/g) and CRE exhibited different colors in varying pH buffers (2-13).
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
October 2024
To deeply understand the chemical components and functional differences of the rhizomes from different Coptis species, this study employed widely targeted metabolomics for the metabolic profiling of C. chinensis, C. deltoidea, and C.
View Article and Find Full Text PDFIntroduction: Altered epigenetic reprogramming enables breast cancer cells to adapt to hypoxic stress. Hypoxic microenvironment can alter immune cell infiltration and function, limiting the effectiveness of immunotherapy.
Objectives: The study aimed to identify how fat mass and obesity-associated protein (FTO) helps breast cancer cells cope with the hypoxic microenvironment and the mechanisms behind breast cancer cell resistance to tumor immunity.
A comprehensive understanding of the formation of mineral-associated organic matter (MAOM) is a prerequisite for the sustainable management of soil carbon (C) and the development of effective long-term strategies for C sequestration in soils. Nevertheless, the precise manner by which microbial and mineral properties drive MAOM formation efficiency and its subsequent response to elevated temperature at the regional scale remains unclear. Here, we employed isotopically labelled laboratory incubations (at 15°C and 25°C) with soil samples from a ~3000 km transect across the Tibetan Plateau to elucidate the mechanisms underlying MAOM formation and its temperature response.
View Article and Find Full Text PDFJ Ophthalmic Inflamm Infect
December 2024
Background: Endophthalmitis is an ophthalmologic emergency requiring accurate and rapid diagnosis for treatment. Currently, the diagnosis commonly relies on culture and molecular biology, which falls short of clinical rapid diagnosis. The purpose of this study was to evaluate the feasibility of a self-build Microfluidic Real-time Polymerase Chain Reaction (RT-PCR) System for rapidly identifying potential pathogens of endophthalmitis.
View Article and Find Full Text PDFThe influence of circulating white blood cells and inflammatory factors on pruritus is gradually recognized by the public, but the specific causal relationship is still unknown. In this study, we included inflammatory cytokine profiles from 8293 healthy subjects, genetic data on blood cells from various ethnic and ancestry backgrounds, including 746,667 individuals, and 1370 patients of European descent with pruritus for a bidirectional 2-sample Mendelian randomization (MR) analysis. We employed several robust statistical methods, including the inverse variance weighted, weighted median, and the MR-Egger method.
View Article and Find Full Text PDFSensors (Basel)
November 2024
Humanoid robots are typically designed for static environments, but real-world applications demand robust performance under dynamic, uncertain conditions. This paper introduces a perceptive motion planning and control algorithm that enables humanoid robots to navigate and operate effectively in environments with unpredictable kinematic and dynamic disturbances. The proposed algorithm ensures synchronized multi-limb motion while maintaining dynamic balance, utilizing real-time feedback from force, torque, and inertia sensors.
View Article and Find Full Text PDFTo enhance the functionality of honey, particularly its antioxidant capacity, the incorporation of polyphenols (AMPs) is an effective approach. The preparation technology and antioxidant activity of AMP added to honey were studied. AMP was extracted with ethanol and its components were analyzed and then mixed evenly with honey in different addition amounts (0.
View Article and Find Full Text PDFThe pathogenesis of diabetic peripheral neuropathy (DPN) has not been fully elucidated, and treatment options are limited. Currently, the main strategies for treating DPN are strict glycemic control and symptomatic pain relief. In this editorial, we comment on an article by Li which suggested that modulating the gut microbiota using traditional Chinese medicine (TCM) may be a promising strategy for alleviating DPN symptoms.
View Article and Find Full Text PDFMagnetic phase transitions play crucial roles in various material applications, including sensors, actuators, information storage, magnetic refrigeration, and so on. Typically, these magnetic phase transitions exhibit discontinuous first-order phase transitions. When a material undergoes a magnetic phase transition, it often exhibits simultaneous changes in both its crystal and electronic structures.
View Article and Find Full Text PDFIntroduction: Cell fate determination and transition are of paramount importance in biology and medicine. Naive pluripotency could be achieved by reprogramming differentiated cells. However, the mechanism is less clear.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
December 2024
Background: Dorper sheep are celebrated for their fast maturation and superior meat quality, with some shedding their wool each spring. Wool shedding occurs naturally due to the hair follicle (HF) cycle, but its regulatory mechanisms remain unclear and need further investigation.
Results: In this study, shedding and non-shedding sheep were selected from the same Dorper flock.
Background: Sex differences in blood pressure (BP) levels and hypertension are important and the role of socioeconomic status (SES) in sex differences in hypertension remains unclear.
Objective: This study aimed to evaluate the impact of SES on sex differences of hypertension in a nationally representative survey study.
Methods: A total of 98,658 participants aged ≥18 years who have lived in their current residence for ≥6 months were recruited from 162 study sites across mainland China.
The skin is the largest organ in the human body and is made up of various cells and structures. Over time, the skin will age, which is not only influenced by internal factors, but also by external environmental factors, especially ultraviolet radiation. Aging causes immune system weakening in the elderly, which makes them more susceptible to dermatosis, such as type 2 inflammatory mediated pruritus.
View Article and Find Full Text PDFDuring the past 40 years, the prevalence of diabetes in China has increased from less than 1·0% in 1980 to 12·4% in 2018, an increase in line with the rapid growth of the nation's economy. To address such a burden, the Healthy China 2030 initiative and subsequent Action Plan, including a diabetes prevention and control campaign, were launched. A shift from a disease-centred approach to a health-centred approach and from treatment to prevention is the core of the Action Plan and diabetes management in China.
View Article and Find Full Text PDFTriglyceride (TG)/HDL-C ratio (THR) is a surrogate predictor of hyperinsulinemia. To identify novel genetic loci for THR change over time (ΔTHR), we conducted genome-wide association study (GWAS) and genome-wide linkage scan (GWLS) among nondiabetic Europeans from the Long Life Family Study (n = 1,384). Subjects with diabetes or on dyslipidemia medications were excluded.
View Article and Find Full Text PDFObjective: To systematically evaluate the risk factors of conversion to thoracotomy in thoracoscopic surgery (VATS) for lung cancer, and to provide a theoretical basis for the development of personalized surgical plans.
Methods: CNKI, Wanfang, VIP, CBM, PubMed, Cochrane Library, Web of Science, and Embase databases were searched by computer from the establishment of the database to March 2024. Relevant studies on the risk factors of conversion to thoracotomy in VATS for lung cancer were searched.
Lung disease development involves multiple cellular processes, including inflammation, cell death, and proliferation. Research increasingly indicates that autophagy and its regulatory proteins can influence inflammation, programmed cell death, cell proliferation, and innate immune responses. Autophagy plays a vital role in the maintenance of homeostasis and the adaptation of eukaryotic cells to stress by enabling the chelation, transport, and degradation of subcellular components, including proteins and organelles.
View Article and Find Full Text PDFObjective: To systematically review the intervention effects of humor therapy on older adults.
Methods: We searched Chinese and English databases for studies on humor therapy interventions for older adults and performed meta-analysis using stata 15 software.
Results: A total of 9 randomized controlled trials and 4 quasi-experimental studies, with a pooled sample of 984 participants, met our inclusion criteria.