TGF-β1 Mediates Novel-m0297-5p Targeting to Participate in the Proliferation of Ovarian Granulosa Cells in Small-Tailed Han Sheep.

MiRNAs regulate follicle development and atresia, steroid production, granulosa cell (GC) proliferation, and apoptosis. However, the target genes and the functioning of novel miRNAs remain unexplored. We reveal the targeting relationship between novel-m0297-5p and and the specific regulatory mechanism of GC proliferation in small-tailed Han sheep using whole transcriptomic sequencing.

Integrative Targeted Metabolomics and Transcriptomics Reveal the Mechanism of Leaf Coloration in 'Sakimp005'.

One of the most important characteristics of ornamental plants is leaf color, which enhances the color of plant landscapes and attracts pollinators for reproduction. The leaves of 'Sakimp005' are initially green, then the middle part appears yellow, then gradually become white, while the edge remains green. In the study, leaves of 'Sakimp005', in four developmental stages (S1-G, S2-C, S3-C, and S4-C), were selected for the determination of pigment content, chromaticity values, integrative metabolomics, and transcriptomics analyses.

Transcriptomic Alterations in the Hippocampus and Prefrontal Cortex of Rats with Chronic Unpredictable Stress Induced by Low-Intensity Pulsed Ultrasound.

In our previous study, low-intensity pulsed ultrasound stimulation (LIPUS), a novel noninvasive neuromodulation tool, effectively alleviated depression-like behaviors in a rat model of depression. However, the underlying mechanisms remain unclear. The present study aimed to elucidate the relevant mechanisms through transcriptomic research.

The impact of global change factors on the functional genes of soil nitrogen and methane cycles in grassland ecosystems: a meta-analysis.

Soil functional genes in grasslands are crucial for processes like nitrogen fixation, nitrification, denitrification, methane production, and oxidation, integral to nitrogen and methane cycles. However, the impact of global changes on these genes is not well understood. We reviewed 84 studies to examine the effects of nitrogen addition (N), warming (W), increased precipitation (PPT +), decreased precipitation (PPT-), and elevated CO (eCO) on these functional genes.

Evaluation of postoperative renal function in infants with congenital hydronephrosis using ROI from ultrasound technique in renography.

The aim of this study was to assess the efficacy of GFR measured using ROI from ultrasound technique in diuretic renography for evaluating postoperative outcomes in infants under one year old with congenital hydronephrosis. A retrospective analysis was conducted on thirty infants who underwent abdominal ultrasound and diuretic renography before and after surgery, obtaining preoperative and postoperative gGFRs and uGFRs (measured using ROI from ultrasound technique) determined using the Gates method and ultrasonic-assisted drawing ROI technique, respectively. A comparative study was performed on total GFR as well as individual kidney GFR before and after intervention.

Global Distributions of Reactive Iron and Aluminum Influence the Spatial Variation of Soil Organic Carbon.

Organic carbon persistence in soils is predominantly controlled by physical accessibility rather than by its biochemical recalcitrance. Understanding the regulation of soil iron (Fe) and aluminum (Al) (hydr)oxides, playing a dominant role in mineral protection, on soil organic carbon (SOC) would increase the reliable projections of the feedback of terrestrial ecosystems to global warming. Here, we conducted a continental-scale survey in China (341 sites) and a global synthesis (6786 observations) to reveal the global distributions of Fe/Al (hydr)oxides and their effects on SOC storage in terrestrial ecosystems.

The phosphorylation of Smad3 by CaMKIIγ leads to the hepatocyte pyroptosis under perfluorooctane sulfonate exposure.

Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant and accumulated in the liver of mammals. PFOS exposure is closely associated with the development of pyroptosis. Nevertheless, the underlying mechanism is unclear.

Research progress in ultrasound and its assistance treatment to reduce food allergenicity: Mechanisms, influence factor, application and prospect.

Food allergy is a serious public health problem, which is mainly induced by food allergens (mainly allergenic proteins). Ultrasound can change protein structure, suggesting its potential to decrease food allergenicity. The review concluded the mechanism and influence factors of ultrasound to reduce food allergenicity.

Corrigendum: Ginsenoside Rg1 ameliorates neuroinflammation via suppression of connexin43 ubiquitination to attenuate depression.

[This corrects the article DOI: 10.3389/fphar.2021.

How does green credit affect industrial green transformation? Mechanism discussion and empirical test.

Sustainable development has become a strategic consensus in response to the global environmental problems. Green credit is a major policy innovation that promotes the transformation of economic development mode and industrial green transformation (IGT). Using provincial panel data from 2005 to 2020, we investigate the effect of green credit on IGT using a systematic GMM model, a dynamic threshold model, as well as the possible nonlinear relationship.

Interface Engineering of the CuMnO/CeO Heterostructure for Highly Efficient Electrocatalytic Nitrate Reduction to Ammonia.

The electrochemical nitrate reduction reaction (NORR) is considered a sustainable technology to convert the nitrate pollutants to ammonia. However, developing highly efficient electrocatalysts is necessary and challenging given the slow kinetics of the NORR with an eight-electron transfer process. Here, a CuMnO (CMO)/CeO heterostructure with rich interfaces is designed and fabricated through an electrospinning and postprocessing technique.

Dynamic 3D Point Cloud Sequences as 2D Videos.

Dynamic 3D point cloud sequences serve as one of the most common and practical representation modalities of dynamic real-world environments. However, their unstructured nature in both spatial and temporal domains poses significant challenges to effective and efficient processing. Existing deep point cloud sequence modeling approaches imitate the mature 2D video learning mechanisms by developing complex spatio-temporal point neighbor grouping and feature aggregation schemes, often resulting in methods lacking effectiveness, efficiency, and expressive power.

Correlation between serum phosphate and all-cause mortality in critically ill patients with coronary heart disease accompanied by chronic kidney disease: a retrospective study using the MIMIC-IV database.

Background: The adverse clinical endpoints of cardiovascular and kidney diseases are correlated with increased serum phosphate levels. However, in critically ill patients with coronary heart disease (CHD) accompanied by chronic kidney disease (CKD), the prognostic value of serum phosphate remains unclear.

Methods: Patients' medical records from the Medical Information Mart for Intensive Care IV database who had concomitant CKD and CHD were classified into four distinct groups in this large retrospective observational cohort study based on the quartiles of serum phosphate levels.

Perfluorooctane sulfonate induces ferroptosis-dependent non-alcoholic steatohepatitis via autophagy-MCU-caused mitochondrial calcium overload and MCU-ACSL4 interaction.

The incidence of nonalcoholic steatohepatitis (NASH) is related with perfluorooctane sulfonate (PFOS), yet the mechanism remains ill-defined. Mounting evidence suggests that ferroptosis plays a crucial role in the initiation of NASH. In this study, we used mice and human hepatocytes L-02 to investigate the role of ferroptosis in PFOS-induced NASH and the effect and molecular mechanism of PFOS on liver ferroptosis.

A novel phage putative depolymerase, Depo16, has specific activity against K1 capsular-type .

, especially hypervirulent (hvKP), is a common opportunistic pathogen that often causes hospital- and community-acquired infections. Capsular polysaccharide (CPS) is an important virulence factor of . Some phages encode depolymerases that can recognize and degrade bacterial polysaccharides.

Enhanced trajectory tracking for quadrotors: disturbance observer state feedback control.

This study investigates the dynamics and trajectory tracking of quadcopters by utilizing the Disturbance Observer-based Control (DOBC) algorithm. The quadcopter's dynamic model, which consists of six degrees of freedom, includes both disturbances and uncertainties in the model. The DOBC approach incorporates the disturbance model into the system by introducing it at the input variables.

Iridium nanoparticles supported on polyaniline nanotubes for peroxidase mimicking towards total antioxidant capacity assay of fruits and vegetables.

In this study, a straightforward approach is presented for the first time to anchor Ir nanoparticles on the surface of uniform polyaniline (PANi) nanotubes (NTs), which can be used as an efficient peroxidase (POD)-like catalyst. The morphology and chemical structure of the PANi-Ir nanocomposite are characterized by scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), X-ray diffractometer (XRD), Raman and X-ray photoelectron spectroscopy (XPS) measurements. Owing to the strong interaction between Ir nanoparticles and PANi, a remarkable catalytic enhancement is achieved compared to the bare Ir black catalyst and individual PANi NTs, dominating withan electron transfer mechanism.

Bridging the gap: unleashing the power of non-core departments through interdepartmental collaboration.

Traditional research on firm performance has predominantly emphasized the role of key departments, often underestimating the potential contributions of non-core departments. This study redresses this oversight by investigating the impact of non-core departments on firm performance. Utilizing a comprehensive 20-year dataset from Chinese A-listed firms and employing the endogenous growth model, we scrutinize the influence of non-core departments on enterprise productivity and organizational growth.

Rational design of bimetal phosphide embedded in carbon nanofibers for boosting oxygen evolution.

The development of non-precious metal electrocatalysts for oxygen evolution reaction (OER) is crucial for generating large-scale hydrogen through water electrolysis. In this work, bimetal phosphides embedded in electrospun carbon nanofibers (P-FeNi/CNFs) were fabricated through a reliable electrospinning-carbonization-phosphidation strategy. The incorporation of P-FeNi nanoparticles within CNFs prevented them from forming aggregation and further improved their electron transfer property.

Rationally Construction of Mn-Doped RuO Nanofibers for High-Activity and Stable Alkaline Ampere-Level Current Density Overall Water Splitting.

Nowadays, highly active and stable alkaline bifunctional electrocatalysts toward water electrolysis that can work at high current density (≥1000 mA cm) are urgently needed. Herein, Mn-doped RuO (MnRuO) nanofibers (NFs) are constructed to achieve this object, presenting wonderful hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) performances with the overpotentials of only 269 and 461 mV at 1 A cm in 1 m KOH solution, and remarkably stability under industrial demand with 1 A cm, significantly better than the benchmark Pt/C and commercial RuO electrocatalysts, respectively. More importantly, the assembled MnRuO NFs||MnRuO NFs electrolyzer toward overall water splitting reaches the current density of 10 mA cm with a cell voltage of 1.

Significantly Enhanced Energy-Saving H Production Coupled with Urea Oxidation by Low- and Non-Pt Anchored on NiS-Based Conductive Nanofibers.

Rational designing electrocatalysts is of great significance for realizing high-efficiency H production in the water splitting process. Generally, reducing the usage of precious metals and developing low-potential nucleophiles oxidation reaction to replace anodic oxygen evolution reaction (OER) are efficient strategies to promote H generation. Here, NiS-coated nickel-carbon nanofibers (NiS@Ni-CNFs) are prepared for low-content Pt deposition (Pt-NiS@Ni-CNFs) to attain the alkaline HER catalyst.