Publications by authors named "Siyao Ye"

Three previously undescribed steroid-polyketone conjugates, talarergosteroids A-C (-), together with talarergosteroid D (), which was first identified from a natural source, were isolated from a derived fungus sp. SCNU-F0041. Compounds and bear a complicated 6/6/6/5/6/6 hexacyclic ring system characterized by an oxaspiro[5.

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Article Synopsis
  • - Chemical analysis of the fungus Trichoderma asperellum SCNU-F0048 resulted in the identification of two new steroids, ergosta-4,6,8 (14),22-tetraen-3-(3'-methyl-4'-hydroxyl-γ-butenolide) and camphosterol B, along with two previously known compounds.
  • - The structures of these compounds were confirmed using advanced techniques like nuclear magnetic resonance and single crystal X-ray diffraction analysis.
  • - Compound 1 exhibited significant cytotoxic effects on various tumor cell lines and both compounds 1 and 2 demonstrated strong antifungal properties against Penicillium italicum, with low inhibitory concentration values.
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