Publications by authors named "Siwen Gu"

Under the influence of the polarization effect, the background stray light of the weak starlight simulator and the polarization state of the simulated target star point are doped with each other, so it is difficult to achieve accurate suppression of polarized stray light. In this paper, the mechanism of background stray light induced by the optical engine in a weak starlight simulation device is analyzed, and the principle of mutual doping between stray light and simulated target starlight polarization state is studied. The correlation model of polarization parameters, point source transmittal, and simulated target magnitude was established, and the optimization process of polarization effect was constructed to achieve accurate suppression of polarized stray light in the star map background.

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Background: RNA-binding protein Quaking (QKI) has been linked with the pathogenesis and development of various human malignancies. Herein, we explored the particular role of QKI in breast cancer (BC) progression.

Methods: The methods employed in the study included public dataset analysis, western blot, quantitative real-time PCR (qRT-PCR), cell count kit-8 (CCK8) assay, colony formation assay, flow cytometric analysis, RNA immunoprecipitation (RIP), messenger RNA (mRNA) stability assay, QKI overexpression and knockdown, and Ras p21 protein activator 1 (RASA1) knockdown.

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Pyramidal SnO/CeO nano-heterojunction photocatalysts were successfully synthesized via a facile hydrothermal method. The structural characterization was investigated by using common characterization tools. The content of SnO affected the morphology and photocatalytic performance of the SnO/CeO nano-heterojunctions.

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Thyroid cancer is the fastest growing cancer among all solid tumors in recent decades. Papillary thyroid carcinoma (PTC) is the most predominant type of thyroid cancer. Around 30% of PTC patients with distant metastases and local invasion receive poor prognosis.

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Snail family zinc finger 2 (SLUG) is related to epithelial-mesenchymal transition (EMT). Quaking (QKI) is an RNA binding protein and has been indicated to have a relationship with EMT by recent studies. The prognostic value of SLUG and QKI in breast cancer patients still needs exploration.

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Solute carrier family members control essential physiological functions and are tightly linked to human diseases. Solute carrier family 35 member F2 (SLC35F2) is aberrantly activated in several malignancies. However, the biological function and molecular mechanism of SLC35F2 in papillary thyroid carcinoma (PTC) are yet to be fully explored.

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