Publications by authors named "Sivochalova O"

The review considers problems of reproductive health disorders in night shift workers. In materials of national and foreign authors, ambiguous opinions are presented on the influence, such as on reproductive sphere malignancies development in shift workers. Data of experimental and clnical laboratory studies are presented, that support reproductive pathologies connected with night shift work.

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There was studied the state of health of females in modern sector employment: office workers (group 1) and managers (group 2), and the health of their newborns. There was established the increase of the risk for the development of extragenital disorders in groups 1 and 2 compared with the control. For adreno-genital syndrome OR = 3.

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The article mentiones issues of preserving and strengthening the reproductive health of women workers, dealed by researchers of the laboratory, established in 1974. It describes the developed concept of the reproductive health problems and scientific research areas, developed documents, including legislative fields, formulates main prospects of the laboratory to meet the requirements of the present moment. Noted the role of the Problem Commission "Scientific basis for the reproductive health of workers", in the work of the Scientific Council on medical and environmental issues of workers' health.

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The article presents results obtained in study of relationship between polymorph variants of CYP1A1 and CYP1A2 genes with reproductive and thyroid diseases risk in female workers of petrochemical industry, when compared with reference group females. Variants TD and DD of CYP1A2 gene appeared to be associated with nodes formation in uterus and breast in female workers and reference group females. Following liability markers are obtained: homozygous in rare allele genotype CC of CYP1A1 gene for reproductive and thyroid diseaes (fibrous cystic mastopathy and nodular goitre), heterozygous genotype AG of CYP1A1 gene in uterine myoma and fibrous cystic mastopathy, homozygous in deleted T genotype of CYP1A2 gene in autoimmune thyroiditis.

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The problem of workers reproductive health protection from harmful occupational and environmental exposures is amongst the national priorities due to demographic situation in Russia and decrease of the manpower. Some issues of women's reproductive health disorders are considered from occupational health standpoint. The demographic and epidemiological data on pregnancy course and outcome, birth defects, children's morbidity etc.

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Chemicals in the air of workplace within organic synthesis enterprises could induce reproductive disorders in the female workers. Analysis of polymorphous variants of P450 cytochrome gens and antioxidant defence system helped to reveal genetic markers for risk of reproductive disorders in the female examinees.

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Based on legislation of RF, Occupational Health Ministry and WHO, the authors specified methodology to reveal diseases associated to work, in addition to present system of occupational diseases diagnosis. The article also covers terminology, premises and causation (determining relationships with work) principles. The authors presented models and criteria for causation in consensus and evidence based medicine with computerized and Internet technologies, described contemporary approaches to prophylaxis.

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The article presents results of studies in males participated in anti-terrorist military operations in local conflict areas. Findings are intact general spermogram parameters with lower serum and/or ejaculate levels of glycodeline and inhibin B--that is a precondition for high risk reproductive disorders under battle stress.

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The article covers problem of occupational and environmental hazards' influence on reproductive health. The authors present topics on preservation of reproductive health in international systems of chemical safety.

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The authors studied work conditions of medical personnel and health state including reproductivity, according to periodic medical examinations data, transitory disablement morbidity, occupational morbidity, questioning, clinical, laboratory and instrumental investigations. Reproductive health was assessed through gynecologic observations, course of pregnancy and delivery, the authors evaluated their relationships with work and identified risk groups for target prophylaxis.

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Galvanic production workers appeared to have mainly humoral immunity activated--sensitization to nickel, reliable prevalence of immune disorders in males over females, significant influence of immune overstrain on frequency of acute respiratory infections and allergic conditions. The authors justified approaches to safe immune prophylaxis of diseases in workers.

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The article covers materials on medical and social problems associated with up-to-date improving the occupational medical service.

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The article covers analysis and summary of data on occupational traumatism among female workers engaged into various economic branches of RF. The authors analysed distribution of victims according to occupational accident types, causes of traumatism, studied dependence on the victims' age and length of service, followed the relationships with possible reproductive disorders.

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The legal and ethical issues related with the protection of population reproductive health, under the conditions of anthropogenic contamination of the environment, including the labor environment, are discussed in the article. A concept of pregnancy planning to ensure a healthy posterity under the mentioned conditioned was formulated. Documents of WHO, ILO and the EU experience in dealing with the issues in question are illustrated.

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Social, economic and other factors appeared to form psychoemotional personal profile of teenager girls living in significant industrial region subjected to pollution with chemicals varying in jeopardy. The studies proved that ecologic factors may play an important role in formation of psychoemotional personal profile. All this could be a pathogenetic basis for endocrine disorders among teenagers and subsequent reproductive disturbances and birth of diseased children.

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The article deals with various aspects of workers' reproductive health care during economic crisis in Russia. Deterioration of health state in children and adults threatens deeper negative demographic trends. The authors discuss basic principles of "Reproductive health as a problem in occupational medicine".

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The issues and prospects of workers' reproductive health as a problem of occupational health in nowadays Russia are outlined with due account for WHO, ILO, EC, etc. concepts and recommendations. Main principles of reproductive health protection are gender approach, additional protection of vulnerable groups, e.

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Modern demographic situation stressed the problems of human reproductive health associated with industrial medical topics. The article suggests to regard a family (child and two parents) as a unit under study in industrial medicine. This methodic approach should work in scientific programs reviewing influence of industrial ecology and environmental factors on reproductivity.

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Problems of ecology do not affect nations individually. Similarly, scientists must participate in seeking solutions to ecologic problems regardless of State borders. The sophistication of certain demographic indices, primarily those of infant and maternal mortality and of population reproduction, is a barometer of a nation's socioeconomic status and the quality of medical care.

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