Antibacterial effects of children's and adults' toothpastes containing different amounts of fluoride: An in vitro study.

Background: In recent years, fluoride concentrations in toothpaste for children and adults have increased. However, the effects of different concentrations on bacterial activity have rarely been compared. We aimed to investigate and compare the antibacterial activity of children's and adults' toothpaste containing 500, 1000‒1100, and 1450‒1500 ppm fluoride.

Comparative proteomic analysis of dental pulp from supernumerary and normal permanent teeth.

Objectives: To obtain and compare the protein profiles of supernumerary and normal permanent dental pulp tissues.

Materials And Methods: Dental pulp tissues were obtained from supernumerary and normal permanent teeth. Proteins were extracted and analyzed by liquid chromatography-tandem mass spectrometry (LC/MS-MS).

Erosive potential of vitamin waters, herbal drinks, carbonated soft drinks, and fruit juices on human teeth: An in vitro investigation.

Background: Dental erosion is the loss of dental hard tissues through the acid dissolution of tooth minerals. One of the major factors that cause erosion is the consumption of acidic food and drinks. This study investigated and compared the effect of vitamin waters, herbal beverages, carbonated soft drinks, and fruit juices on the loss of human dental hard tissue.

High-Throughput Bioprinting of Geometrically-Controlled Pre-Vascularized Injectable Microgels for Accelerated Tissue Regeneration.

Successful integration of cell-laden tissue constructs with host vasculature depends on the presence of functional capillaries to provide oxygen and nutrients to the embedded cells. However, diffusion limitations of cell-laden biomaterials challenge regeneration of large tissue defects that require bulk-delivery of hydrogels and cells. Herein, a strategy to bioprint geometrically controlled, endothelial and stem-cell laden microgels in high-throughput is introduced, allowing these cells to form mature and functional pericyte-supported vascular capillaries in vitro, and then injecting these pre-vascularized constructs minimally invasively in-vivo.

3D-printed microgels supplemented with dentin matrix molecules as a novel biomaterial for direct pulp capping.

Objectives: To develop a 3D-printed, microparticulate hydrogel supplemented with dentin matrix molecules (DMM) as a novel regenerative strategy for dental pulp capping.

Materials And Methods: Gelatin methacryloyl microgels (7% w/v) mixed with varying concentrations of DMM were printed using a digital light projection 3D printer and lyophilized for 2 days. The release profile of the DMM-loaded microgels was measured using a bicinchoninic acid assay.

Efficacy of Dental Barriers in Aerosols and Splatters Reduction During an Ultrasonic Scaling: An Study.

Background: Barrier enclosure systems were suggested as the protective equipment for aerosol-generating procedures.

Objective: The aim of this study was to investigate the efficiency of dental barriers in aerosols and splatters reduction during an ultrasonic scaling.

Materials And Methods: Two types of dental barriers: (1) metal frame with plastic wrap (MFPW) and (2) plastic shield chamber (PSC) were investigated.

Efficacy of extraoral suction devices in aerosol and splatter reduction during ultrasonic scaling: A laboratory investigation.

Ultrasonic scaling generates aerosols and splatters contaminated with microorganisms, increasing the risk of disease transmission in the dental office. The present study aimed to evaluate the effectiveness of extraoral suction (EOS) units in aerosol and splatter reduction during ultrasonic scaling. Ultrasonic scaling was conducted on a dental manikin headset to simulate a scaling procedure.

Odontogenic gene expression profile of human dental pulp-derived cells under high glucose influence: a microarray analysis.

Unlabelled: Hyperglycemia, a major characteristic of diabetes, is considered to play a vital role in diabetic complications. High glucose levels have been found to inhibit the mineralization of dental pulp cells. However, gene expression associated with this phenomenon has not yet been reported.

Equivalence of human and bovine dentin matrix molecules for dental pulp regeneration: proteomic analysis and biological function.

Objective: To compare proteomics and biological function of human dentin matrix molecules (hDMMs) and bovine dentin matrix molecules (bDMMs).

Design: Dentin powder from human or bovine teeth (n = 4) was demineralized in 10% (v/v) ethylenediaminetetraacetic acid for 7 days. The extracts were dialyzed, lyophilized and proteins were characterized using liquid chromatography-tandem mass spectrometry and shotgun proteomic analysis.

3D Printing of Microgel-Loaded Modular Microcages as Instructive Scaffolds for Tissue Engineering.

Biomaterial scaffolds have served as the foundation of tissue engineering and regenerative medicine. However, scaffold systems are often difficult to scale in size or shape in order to fit defect-specific dimensions, and thus provide only limited spatiotemporal control of therapeutic delivery and host tissue responses. Here, a lithography-based 3D printing strategy is used to fabricate a novel miniaturized modular microcage scaffold system, which can be assembled and scaled manually with ease.

High Glucose Affects Proliferation, Reactive Oxygen Species and Mineralization of Human Dental Pulp Cells.

Diabetes is a group of metabolic disorders that can lead to damage and dysfunction of many organs including the dental pulp. Increased inflammatory response, reduction of dentin formation and impaired healing were reported in diabetic dental pulp. Hyperglycemia, which is a main characteristic of diabetes, was suggested to play a role in many diabetic complications.