Publications by authors named "Sivakumar Ragul"
Tissue Barriers
October 2024
Article Synopsis
- The text discusses the limitations in developing new therapies due to inadequate predictive in vitro models and presents Organ-on-chip (OOC) technologies as a promising solution for improved tissue and disease modeling.
- It introduces a scalable microfluidic platform called AKITA, designed for high, medium, and low throughput applications compatible with existing laboratory workflows in a standardized format.
- AKITA is specifically optimized for studying vascularized biological barriers like the blood-brain barrier, using precise flow control and integrated sensors to monitor barrier integrity, ultimately aiding in preclinical drug testing and precision medicine.
