Analysis of Differentially Expressed Genes in Coronary Artery Disease by Integrated Microarray Analysis.

Coronary artery disease (CAD) is a major cause of end-stage cardiac disease. Although profound efforts have been made to illuminate the pathogenesis, the molecular mechanisms of CAD remain to be analyzed. To identify the candidate genes in the advancement of CAD, microarray dataset GSE23766 was downloaded from the Gene Expression Omnibus database.

Contribution of community pharmacists in educating the asthma patients.

Unlabelled: : In asthma, the preventive measures taken by patients play an important role in improving life span and quality of life. This can be done more efficiently by community pharmacist by providing patient counseling and improving knowledge of patient about disease, risk factors, medication management and preventive measures to control asthma. : The objective of the study was to evaluate the contribution of community pharmacists in improvement of life span and quality of life of asthma patients.

Preparation and characterization of novel PBAE/PLGA polymer blend microparticles for DNA vaccine delivery.

Context: Poly(beta-amino ester) (PBAE) with its pH sensitiveness and Poly(lactic-co-glycolic acid) (PLGA) with huge DNA cargo capacity in combination prove to be highly efficient as DNA delivery system.

Objective: To study the effectiveness of novel synthesized PBAE polymer with PLGA blend at different ratios in DNA vaccine delivery.

Methods: In the present study, multifunctional polymer blend microparticles using a combination of PLGA and novel PBAE polymers A1 (bis(3-(propionyloxy)propyl)3,3'-(propane-1,3-diyl-bis(methylazanediyl))dipropanoate) and A2 (bis(4-(propionyloxy)butyl)3,3'-(ethane-1,2-diyl-bis(isopropylazanediyl))dipropanoate) at different ratios (85:15, 75:25, and 50:50) were prepared by double emulsion solvent removal method.